Centre for Experimental Biophysical Chemistry

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  • Currently displaying 121 - 140 of 1229 publications
Author(s)
Publication title
Journal Name
Publication year
BPS2025 - Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwöger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.377)
BPS2025 - Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, T Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.217)
BPS2025 - Investigating α-synuclein liquid condensates transition to an irreversible aggregated state
IA Edu, A Levin, T Sneideris, CM Fischer, TPJ Knowles
Biophysical Journal
(2025)
124
(doi: 10.1016/j.bpj.2024.11.489)
On the reversibility of amyloid fibril formation
T Pálmadóttir, J Getachew, L Ortigosa-Pascual, E Axell, J Wei, U Olsson, TPJ Knowles, S Linse
Biophysics reviews
(2025)
6
(doi: 10.1063/5.0236947)
Competing addition processes give distinct growth regimes in the assembly of 1D filaments.
SA Akram, T Brown, S Whitelam, G Meisl, TPJ Knowles, JD Schmit
Biophys J
(2025)
124
(doi: 10.1016/j.bpj.2025.01.018)
SynPull: a novel method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
S Kedia, E Fertan, Y Wu, YP Zhang, G Meisl, JYL Lam, F K Wiseman, WA McEwan, A Quaegebeur, MG Spillantini, JSH Danial, D Klenerman
Cell Chemical Biology
(2025)
32
(doi: 10.1016/j.chembiol.2025.01.001)
Lipid-induced condensate formation from the Alzheimer’s Aβ peptide triggers amyloid aggregation
G Šneiderienė, A González Díaz, SD Adhikari, J Wei, T Michaels, T Šneideris, S Linse, M Vendruscolo, K Garai, TPJ Knowles
Proceedings of the National Academy of Sciences
(2025)
122
(doi: 10.1073/pnas.2401307122)
Transforming an ATP-dependent enzyme into a dissipative, self-assembling system
Y Li, J Zhu, Z Zhang, J Wei, F Wang, G Meisl, TPJ Knowles, EH Egelman, FA Tezcan
Nat Chem Biol
(2025)
21
(doi: 10.1038/s41589-024-01811-1)
Detecting the Undetectable: Advances in Methods for Identifying Small Tau Aggregates in Neurodegenerative Diseases
D Böken, Y Wu, Z Zhang, D Klenerman
Chembiochem
(2025)
26
(doi: 10.1002/cbic.202400877)
Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwoger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
BIOPHYSICAL JOURNAL
(2025)
123
Quantifying and predicting antibody non-specificity in the clinical landscape: Microfluidics and machine learning
E de Csillery, H Ausserwoger, M Oeller, I Waibel, R Akbar, A Abrudan, G Krainer, G Invernizzi, P Arosio, N Lorenzen, T Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Quantifying temperature-induced changes in protein interactions and phase behavior using high-throughput droplet microfluidics
CM Fischer, H Ausserwoger, T Sneideris, D Qian, R Scrutton, S Qamar, P St George-Hyslop, TP Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Extracellular phase separation mediates storage and release of thyroglobulin in the thyroid follicular lumen
Y Yao, N Erkamp, T Sneideris, X Yang, R Scrutton, MM Schneider, CM Fischer, E Schoenmakers, N Schoenmakers, T Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Digital seed amplification quantifies the increase in seeding- competent aggregates in Parkinson's patients' CSF
A Levin, S Cai, H Ausserwoeger, G Meisl, D Qian, R Scrutton, IA Edu, G Krainer, T Sneideris, L Chai, W Arter, TP Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Digital seed amplification quantifies the increase in seeding-competent aggregates in Parkinson's patients' CSF
A Levin, S Cai, H Ausserwoeger, G Meisl, D Qian, R Scrutton, IA Edu, G Krainer, T Sneideris, L Chai, W Arter, TP Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Investigating the role of sequence patterning in the mixing of polymer dense phases
LL Good, TP Knowles, RB Best
BIOPHYSICAL JOURNAL
(2025)
124
Digestibility and enteric release achieved with microencapsulates made from emulsion-templated plant proteins
LW Browning, H Wang, JW Taylor, P Wilde, M Rodriguez-Garcia, LAM Holland, TPJ Knowles
Sustainable Food Technology
(2025)
3
(doi: 10.1039/d4fb00375f)
Detecting alpha-synuclein aggregates with small molecules on single-molecule array
JYL Lam, TS Chisholm, H Almahli, EA English, Z Xia, Y Wu, MR Cheetham, CA Hunter, D Klenerman
Chemical Science
(2025)
16
(doi: 10.1039/d4sc07649d)
BPS2025-SpringSaLaDpy: Python-based analysis and visualization of molecular clusters in 3D
HL Perone, A Chattaraj, ML Blinov, S Cai, H Ausserwoeger, G Meisl, T Sneideris, L Chai, W Arter, TP Knowles, Y Hamied
BIOPHYSICAL JOURNAL
(2025)
124
Investigating a-synuclein liquid condensates transition to an irreversible aggregated state
IA Edu, A Levin, T Sneideris, CM Fischer, TPJ Knowles
BIOPHYSICAL JOURNAL
(2025)
124
Yusuf Hamied Department of Chemistry
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CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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