Centre for Experimental Biophysical Chemistry

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  • Currently displaying 121 - 140 of 1298 publications
Author(s)
Publication title
Journal Name
Publication year
Quantifying collective interactions in biomolecular phase separation.
H Ausserwöger, E de Csilléry, D Qian, G Krainer, TJ Welsh, T Sneideris, TM Franzmann, S Qamar, NA Erkamp, J Nixon-Abell, M Kar, P St George-Hyslop, AA Hyman, S Alberti, RV Pappu, TPJ Knowles
Nature communications
(2025)
16
(doi: 10.1038/s41467-025-62437-y)
Current practices in the study of biomolecular condensates: a community comment
S Alberti, P Arosio, RB Best, S Boeynaems, D Cai, R Collepardo-Guevara, GL Dignon, R Dimova, S Elbaum-Garfinkle, NL Fawzi, M Fuxreiter, AS Gladfelter, A Honigmann, A Jain, JA Joseph, TPJ Knowles, K Lasker, EA Lemke, K Lindorff-Larsen, R Lipowsky, J Mittal, S Mukhopadhyay, S Myong, RV Pappu, K Rippe, TA Shelkovnikova, AG Vecchiarelli, S Wegmann, H Zhang, M Zhang, C Zubieta, M Zweckstetter, D Dormann, T Mittag
Nature Communications
(2025)
16
(doi: 10.1038/s41467-025-62055-8)
A Charge-Driven Strategy for Covalent Modification and Modulation of Biomolecular Condensates
Z Chen, L Liu, J Cattin, TPJ Knowles, GJL Bernardes
J Am Chem Soc
(2025)
147
(doi: 10.1021/jacs.5c06625)
Diffusing protein binders to intrinsically disordered proteins
C Liu, K Wu, H Choi, HL Han, X Zhang, JL Watson, G Ahn, JZ Zhang, S Shijo, LL Good, CM Fischer, AK Bera, A Kang, E Brackenbrough, B Coventry, DR Hick, S Qamar, X Li, J Decarreau, SR Gerben, W Yang, I Goreshnik, D Vafeados, X Wang, M Lamb, A Murray, S Kenny, MS Bauer, AN Hoofnagle, P Zhu, TPJ Knowles, D Baker
Nature
(2025)
644
(doi: 10.1038/s41586-025-09248-9)
Kinetics of seeded protein aggregation: Theory and application.
AJ Dear, G Meisl, J Hu, TPJ Knowles, S Linse
J Chem Phys
(2025)
163
(doi: 10.1063/5.0273677)
Small‐diffusible aggregates, plaques, tangles, and dynamic equilibria: Untangling Alzheimer's disease
E Fertan, G Meisl, D Klenerman
(2025)
21
Small-diffusible aggregates, plaques, tangles, and dynamic equilibria: Untangling Alzheimer's disease.
E Fertan, G Meisl, D Klenerman
Alzheimer's & Dementia
(2025)
21
(doi: 10.1002/alz.70462)
Female labour at Bletchley Park: reality and (romantic) fiction
T Knowles, C Smith
Intelligence & National Security
(2025)
40
(doi: 10.1080/02684527.2025.2506282)
Global kinetic model of lipid-induced α-synuclein aggregation and its inhibition by small molecules
A Stevenson, R Staats, AJ Dear, D Voderholzer, JE Dreier, G Meisl, R Guido, TPJ Knowles, C Galvagnion, AK Buell, M Vendruscolo, TCT Michaels
Proc Natl Acad Sci U S A
(2025)
122
(doi: 10.1073/pnas.2422427122)
On-Chip De Novo Production of mRNA Vaccine in Lipid Nanoparticles
S Zilberzwige-Tal, A Levin, A Ezra, U Elia, G Finkelstein-Zuta, T Kreiser, L Gershon, M Goldsmith, E Kon, Y Navon, O Cohen, TP Knowles, D Peer, E Gazit
Small
(2025)
21
(doi: 10.1002/smll.202500114)
Patch deconvolution for Fourier light-field microscopy
B Fu, CL Jones, D Heraghty, S Yang, C O’Brien-Ball, V Junghans, H Yang, TPJ Knowles, LE Weiss, RA Fernandes, SF Lee
(2025)
(doi: 10.1101/2025.06.13.659385)
Small tau aggregates exhibit disease-specific molecular profiles across tauopathies
D Böken, M Huang, Y Wu, E Fertan, JYL Lam, G Meisl, S Baig, JB Rowe, C Smith, A Quaegebeur, D Cox, WA McEwan, D Klenerman
(2025)
(doi: 10.1101/2025.06.10.658934)
Volumetric single-molecule tracking inside subcellular structures
S Daly, JE Chambers, C Jones, B Fu, JD Manton, JS Beckwith, SJ Marciniak, DC Gershlick, SF Lee
(2025)
(doi: 10.1101/2025.06.09.658280)
Microfluidics for protein interaction studies: current methods, challenges, and future perspectives
MM Schneider, TPJ Knowles, S Keller, G Krainer
European biophysics journal : EBJ
(2025)
(doi: 10.1007/s00249-025-01763-x)
DNA Partitioning Modulates Liquid-to-Solid Transitions and the Internal Microstructure of FUS Condensates
D Ilhamsyah, C Luong, S Qamar, P St George-Hyslop, J MacKay, LA Ju, TPJ Knowles, D Vigolo, Y Shen
(2025)
(doi: 10.1101/2025.06.03.657213)
Molecular mechanisms of condensate modulation from energy-dominance analysis
D Qian, H Ausserwoger, WE Arter, RM Scrutton, TJ Welsh, T Kartanas, N Ermann, S Qamar, CM Fischer, T Sneideris, P St George-Hyslop, RV Pappu, TPJ Knowles
Physical Review Applied
(2025)
23
(doi: 10.1103/physrevapplied.23.064017)
Transcript Identification Using Arrayed Hydrogels with TrapFISH
DB Morse, Z Toprakcioglu, A Denduluri-Marthi, JD Brenton, CJ Thomas, TPJ Knowles
Advanced Materials Technologies
(2025)
10
(doi: 10.1002/admt.202401953)
Exploring the Liquid-liquid Phase Separation and Membrane Interaction of Human Golgi Reassembly and Stacking Proteins
E Kava, T Agarwal, G Cereghetti, T Knowles, A Costa
EUROPEAN BIOPHYSICS JOURNAL
(2025)
54
Peptide self-assembly enables design of long-acting therapeutics
T Herling, J Wei, S Genapathy, C Rivera, M Persson, P Gennemark, D Workman, H Bolt, M Arteta, S Will, D Hornigold, T Knowles, AG Dos Santos
EUROPEAN BIOPHYSICS JOURNAL
(2025)
54
Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
S Goldsworthy, E Fertan, P Dyal, S Domoney, FJ Livesey, D Klenerman, R Patani, C Hung
(2025)
(doi: 10.1101/2025.05.27.656416)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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