Centre for Experimental Biophysical Chemistry

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  • Currently displaying 41 - 60 of 1298 publications
Author(s)
Publication title
Journal Name
Publication year
Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers
H Yuan, Z Yang, C Yuan, S Shankar, A Levin, T Lv, Z Wang, W Sun, J Sitton, P-A Cazade, Y Dan, Y Tang, L Adler-Abramovich, Y Cao, S Rencus-Lazar, D Thompson, D Kurouski, TPJ Knowles, LJW Shimon, G Wei, B Xue, R Yang, E Gazit
Nat Commun
(2026)
17
(doi: 10.1038/s41467-026-71043-5)
Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner.
M Mosconi, C Leonardi, Z Armour-Garb, B Rocutto, M Beeg, G Meisl, L Ortigosa-Pascual, L Broggini, M Salmona, S Ricagno, TPJ Knowles, L Diomede
Proceedings of the National Academy of Sciences of the United States of America
(2026)
123
(doi: 10.1073/pnas.2532775123)
Reversibility and β-sheet formation are decoupled in tau condensate ageing
CM Fischer, IA Edu, T Šneideris, I Baronaite, Z Toprakcioglu, L-T Deck, D Qian, R Scrutton, L Dreyer, J Wen, DE Otzen, S Wu, S Perrett, TPJ Knowles
Proc Natl Acad Sci U S A
(2026)
123
(doi: 10.1073/pnas.2522993123)
Constructing a single-objective oblique plane microscope (OPM) for fast, multi-colour, high-resolution volumetric fluorescence imaging
Z Zhang, W Hong, Y Wu, A Dey, A Shevchuk, D Klenerman
(2026)
(doi: 10.64898/2026.03.04.709686)
Toll-like receptor signaling outcome is determined by the stoichiometry of the endogenous TRIFosome.
MC Moncrieffe, P Suresh, J Boyle, Y Cui, B Nawalpuri, B Verstak, YP Zhang, Z Zhang, M Taylor, EH Egelman, N Gay, D Klenerman, C Bryant
Sci Adv
(2026)
12
(doi: 10.1126/sciadv.aeb9507)
Scaling Relations of Multicomponent Phase Coexistence Boundaries
D Qian, J Acker, RM Scrutton, CM Fischer, S Qamar, T Sneideris, A Borodavka, TPJ Knowles
Prx Life
(2026)
4
(doi: 10.1103/t2v5-49k4)
Mechanistic insights into the liquid-liquid phase separation of Boc-protected amino acids from simulation and experiment
LL Good, SK Yorke, A Levin, Y Yao, RB Best, TP Knowles
BIOPHYSICAL JOURNAL
(2026)
125
Liquid-liquid phase separation modulates protein pathological aggregation
Y Shen, TP Knowles, DA Weitz, D Vigolo, T Li, D Ilhamsyah
BIOPHYSICAL JOURNAL
(2026)
125
Single-molecule microfluidic diffusional sizing
JJ Fan, R Jacquat, G Krainer, TPJ Knowles, SF Lee
BIOPHYSICAL JOURNAL
(2026)
125
Proteoglycan mimic-based microgel as 3D bioink for constructing high cell-laden scaffolds
S Xu, Y Chen, Y Li, R Zhan, Y Ou, D Tu, TPJ Knowles
BIOPHYSICAL JOURNAL
(2026)
125
Cell-penetrating peptide-conjugated bovine serum albumin nanoparticles for efficient mRNA and siRNA loading and delivery
D Tu, T Sneideris, Y Ou, S Cai, Y Yao, H Yang, TPJ Knowles.
BIOPHYSICAL JOURNAL
(2026)
125
BPS2026 – Nucleation kinetics reveals a distinct biological function space of biomolecular condensates
L-T Deck, SN Pacheco, H Ausserwöger, D Frenkel, NA Erkamp, TPJ Knowles
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1572)
Nanoscopic tau aggregates are not shared intermediates but disease-specific entities across tauopathies
D Böken, M Huang, Y Wu, E Fertan, MW Cotton, G Meisl, JYL Lam, S Baig, JB Rowe, C Smith, A Quaegebeur, D Cox, WA McEwan, D Klenerman
Cell Reports
(2026)
45
(doi: 10.1016/j.celrep.2026.116934)
Structural defects in amyloid-β fibrils drive secondary nucleation.
J Hu, T Scheidt, D Thacker, E Axell, E Stemme, U Łapińska, S Wennmalm, G Meisl, S Curk, M Andreasen, M Vendruscolo, P Arosio, A Šarić, JD Schmit, TPJ Knowles, E Sparr, S Linse, TCT Michaels, AJ Dear
Nat Commun
(2026)
17
(doi: 10.1038/s41467-026-69377-1)
A universal phase-plane model for in vivo protein aggregation.
MW Cotton, A Goriely, D Klenerman, G Meisl
Journal of Chemical Physics
(2026)
164
(doi: 10.1063/5.0312752)
A cell-level model to predict the spatiotemporal dynamics of neurodegenerative disease
S-H Huang, 黃士桓, MW Cotton, TPJ Knowles, D Klenerman, G Meisl
PRX Life
(2026)
4
(doi: 10.1103/f9hz-xvpr)
A cell-level model to predict the spatiotemporal dynamics of neurodegenerative disease
S-H Huang, MW Cotton, TPJ Knowles, D Klenerman, G Meisl
(2026)
(doi: 10.48550/arxiv.2508.15046)
Phase separation and the tumor microenvironment.
W Liu, L Yu, J Xu, Y Yao, TPJ Knowles, Y-L Zhang
Cell communication and signaling : CCS
(2026)
24
(doi: 10.1186/s12964-026-02712-7)
BPS2026 – Cell-penetrating peptide-conjugated bovine serum albumin nanoparticles for efficient mRNA and siRNA loading and delivery
D Tu, T Sneideris, Y Ou, S Cai, Y Yao, H Yang, TPJ Knowles
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.2147)
BPS2026 – Liquid-liquid phase separation modulates protein pathological aggregation
Y Shen, TP Knowles, DA Weitz, D Vigolo, T Li, D Ilhamsyah
Biophysical Journal
(2026)
125
(doi: 10.1016/j.bpj.2025.11.1782)
Yusuf Hamied Department of Chemistry
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