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  • Currently displaying 101 - 120 of 1115 publications
Author(s)
Publication title
Journal Name
Publication year
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
G Šneiderienė, MA Czekalska, CK Xu, AK Jayaram, G Krainer, WE Arter, QAE Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
ACS nano
(2024)
18
Hierarchical Protofilament Intertwining Rules the Formation of Mixed-Curvature Amyloid Polymorphs
J Zhou, S Assenza, M Tatli, J Tian, IM Ilie, EL Starostin, A Caflisch, TPJ Knowles, G Dietler, FS Ruggeri, H Stahlberg, SK Sekatskii, R Mezzenga
Adv Sci (Weinh)
(2024)
11
The Cystic Fibrosis Transmembrane Regulator Controls Tolerogenic Responses to Food Allergens in Mice and Humans
M Emmenegger, C Zografou, Y Dai, L Hoyt, R Gudneppanavar, A Chincisan, H Rehrauer, F Noé, N Zajac, G Meisl, M Schneider, H Nguyen, K Höpker, T Knowles, M Sospedra, R Martin, A Ring, S Leeds, S Eisenbarth, M Egan, E Bruscia, A Aguzzi
(2024)
Electrolyte‐gated organic field‐effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández‐Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
SmartMat
(2024)
5
The role of shear forces in primary and secondary nucleation of amyloid fibrils
E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, G Šneiderienė, D Thacker, TPJ Knowles, E Sparr, S Linse
Proc Natl Acad Sci U S A
(2024)
121
Electrolyte-gated organic field-effect transistors with high operational stability and lifetime in practical electrolytes
D Simatos, M Nikolka, J Charmet, LJ Spalek, Z Toprakcioglu, IE Jacobs, IB Dimov, G Schweicher, MJ Lee, CM Fernández-Posada, DJ Howe, TA Hakala, LWY Roode, V Pecunia, TP Sharp, W Zhang, M Alsufyani, I McCulloch, TPJ Knowles, H Sirringhaus
Smartmat
(2024)
5
The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide
B Li, P Suresh, J Brelstaff, S Kedia, CE Bryant, D Klenerman
eLife
(2024)
13
The delayed kinetics of Myddosome formation explains why amyloid-beta aggregates trigger Toll-like receptor 4 less efficiently than lipopolysaccharide
B Li, P Suresh, J Brelstaff, S Kedia, CE Bryant, D Klenerman
(2024)
Biomolecular condensates with complex architectures via controlled nucleation
NA Erkamp, MAM Verwiel, D Qian, T Sneideris, FA Spaepen, DA Weitz, JCM van Hest, TPJ Knowles
Nature Chemical Engineering
(2024)
1
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-β in Alzheimer’s disease
Z Xia, EE Prescott, A Urbanek, HE Wareing, MC King, A Olerinyova, H Dakin, T Leah, KA Barnes, MM Matuszyk, E Dimou, E Hidari, YP Zhang, JYL Lam, JSH Danial, MR Strickland, H Jiang, P Thornton, DC Crowther, S Ohtonen, M Gómez-Budia, SM Bell, L Ferraiuolo, H Mortiboys, A Higginbottom, SB Wharton, DM Holtzman, T Malm, RT Ranasinghe, D Klenerman, S De
Nature Communications
(2024)
15
Aβ Oligomer Dissociation Is Catalyzed by Fibril Surfaces.
A Dear, D Thacker, S Wennmalm, L Ortigosa-Pascual, EA Andrzejewska, G Meisl, S Linse, T Knowles
ACS Chemical Neuroscience
(2024)
15
Solutes unmask differences in clustering versus phase separation of FET proteins.
M Kar, LT Vogel, G Chauhan, S Felekyan, H Ausserwöger, TJ Welsh, F Dar, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
Nature Communications
(2024)
15
An evolutionarily conserved mechanism controls reversible amyloids of pyruvate kinase via pH-sensing regions
G Cereghetti, VM Kissling, LM Koch, A Arm, CC Schmidt, Y Thüringer, N Zamboni, P Afanasyev, M Linsenmeier, C Eichmann, S Kroschwald, J Zhou, Y Cao, DM Pfizenmaier, T Wiegand, R Cadalbert, G Gupta, D Boehringer, TPJ Knowles, R Mezzenga, P Arosio, R Riek, M Peter
Dev Cell
(2024)
59
Biomolecular condensates sustain pH gradients at equilibrium through charge neutralisation
H Ausserwöger, R Scrutton, C Fischer, T Sneideris, D Qian, E de Csilléry, I Baronaite, K Saar, A Białek, M Oeller, G Krainer, T Franzmann, S Wittmann, J Iglesias-Artola, G Invernizzi, A Hyman, S Alberti, N Lorenzen, T Knowles
(2024)
Polysaccharide functionalization reduces lipid vesicle stiffness.
K Jahnke, M Pavlovic, W Xu, A Chen, TPJ Knowles, LR Arriaga, DA Weitz
Proceedings of the National Academy of Sciences
(2024)
121
Single molecule characterisation of salivary protein aggregates from Parkinson's disease patients – a pilot study
M Furlepa, YP Zhang, E Lobanova, L Kahanawita, G Vivacqua, CH Williams-Gray, D Klenerman
Brain Communications
(2024)
6
Single-Molecule Stoichiometry of Supramolecular Complexes
A McLean, RL Sala, BW Longbottom, AR Carr, JA McCune, SF Lee, OA Scherman
J Am Chem Soc
(2024)
146
Kinetic models reveal the interplay of protein production and aggregation.
J Wei, G Meisl, A Dear, M Oosterhuis, R Melki, C Emanuelsson, S Linse, TPJ Knowles
Chemical science
(2024)
15
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
ST Dada, Z Toprakcioglu, MP Cali, A Röntgen, MC Hardenberg, OM Morris, LK Mrugalla, TPJ Knowles, M Vendruscolo
Nat Commun
(2024)
15
The delayed kinetics of Myddosome formation explains why Aβ aggregates trigger TLR4 less efficiently than LPS
B Li, P Suresh, J Brelstaff, S Kedia, C Bryant, D Klenerman
(2024)