Centre for Experimental Biophysical Chemistry

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  • Currently displaying 161 - 180 of 1108 publications
Author(s)
Publication title
Journal Name
Publication year
The liquid-to-solid transition of FUS is promoted by the condensate surface
Y Shen, A Chen, W Wang, Y Shen, FS Ruggeri, S Aime, Z Wang, S Qamar, JR Espinosa, A Garaizar, P St George-Hyslop, R Collepardo-Guevara, DA Weitz, D Vigolo, TPJ Knowles
Proceedings of the National Academy of Sciences
(2023)
120
(doi: 10.1073/pnas.2301366120)
Electrophysiological In Vitro Study of Long-Range Signal Transmission by Astrocytic Networks.
N Hastings, Y-L Yu, B Huang, S Middya, M Inaoka, NA Erkamp, RJ Mason, A Carnicer-Lombarte, S Rahman, TPJ Knowles, M Bance, GG Malliaras, MRN Kotter
Adv Sci (Weinh)
(2023)
10
(doi: 10.1002/advs.202301756)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, M Schneider, T Welsh, J Fan, Q Peter, E Andrzejewska, G Šneiderienė, M Czekalska, H Ausserwoeger, L Chai, W Arter, K Saar, T Herling, T Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, S Lee, TPJ Knowles
(2023)
(doi: 10.1101/2023.07.12.548675)
Self-replication of Aβ42 aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, T Michaels, T Knowles, A Šarić
(2023)
(doi: 10.1101/2023.07.05.547777)
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding.
E Dimou, T Katsinelos, G Meisl, BJ Tuck, S Keeling, AE Smith, E Hidari, JYL Lam, M Burke, S Lövestam, RT Ranasinghe, WA McEwan, D Klenerman
Cell Reports
(2023)
42
(doi: 10.1016/j.celrep.2023.112725)
Amyloid formation as a protein phase transition
TCT Michaels, D Qian, A Šarić, M Vendruscolo, S Linse, TPJ Knowles
Nature Reviews Physics
(2023)
5
(doi: 10.1038/s42254-023-00598-9)
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
Cell Syst
(2023)
14
(doi: 10.1016/j.cels.2023.05.003)
Amyloids and protein aggregation
S Linse, T Knowles
Chem Sci
(2023)
14
(doi: 10.1039/d2sc90225g)
Formation of Protein Nanoparticles in Microdroplet Flow Reactors
Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo, X Wang, TPJ Knowles
ACS Nano
(2023)
17
(doi: 10.1021/acsnano.3c00107)
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
The Journal of Infectious Diseases
(2023)
228
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains.
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
Proc Natl Acad Sci U S A
(2023)
120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
Chem Rev
(2023)
123
(doi: 10.1021/acs.chemrev.2c00586)
High-density volumetric super-resolution microscopy
S Daly, JF Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, J Beckwith, E Sanders, R Sims, D Klenerman, S Davis, K O’Holleran, S Lee
(2023)
(doi: 10.1101/2023.05.02.539032)
Surfaces for Study of Receptor Dynamics on T Cells.
J McColl, D Klenerman
Methods in Molecular Biology
(2023)
2654
(doi: 10.1007/978-1-0716-3135-5_3)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
bioRxiv
(2023)
(doi: 10.1101/2023.03.22.533832)
The central role of microvilli in shaping T-cell responses
D Klenerman
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-36855-9)
Multidimensional Protein Solubility Optimization with an Ultrahigh- Throughput Microfluidic Platform
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
Analytical chemistry
(2023)
95
(doi: 10.1021/acs.analchem.2c05495)
Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly
A Kamada, Z Toprakcioglu, TPJ Knowles
Biomacromolecules
(2023)
24
(doi: 10.1021/acs.biomac.2c01479)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum.
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
Biosensors and Bioelectronics
(2023)
228
(doi: 10.1016/j.bios.2023.115196)
Yusuf Hamied Department of Chemistry
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