Centre for Experimental Biophysical Chemistry

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  • Currently displaying 241 - 260 of 1124 publications
Author(s)
Publication title
Journal Name
Publication year
Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers.
TCT Michaels, AJ Dear, SIA Cohen, M Vendruscolo, TPJ Knowles
The Journal of chemical physics
(2022)
156
(doi: 10.1063/5.0077609)
Analytical solution to the Flory-Huggins model
D Qian, T Michaels, T Knowles
(2022)
(doi: 10.1101/2022.04.23.489256)
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic.
R Limbocker, S Errico, D Barbut, TPJ Knowles, M Vendruscolo, F Chiti, M Zasloff
Natural product reports
(2022)
39
(doi: 10.1039/d1np00042j)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42Aggregation
K Baumann, M Sanguanini, O Rimon, G Šneiderienė, H Greer, D Thacker, M Schneider, S Linse, T Knowles, M Vendruscolo
(2022)
(doi: 10.1101/2022.04.16.488542)
resPAINT: Accelerating volumetric super-resolution localisation microscopy by active control of probe emission
E Sanders, A Carr, E Bruggeman, M Koerbel, S Benaissa, R Donat, AM Santos, J McColl, K O’Holleran, D Klenerman, S Davis, S Lee, A Ponjavic
(2022)
(doi: 10.1101/2022.04.14.488333)
Micromechanics of soft materials using microfluidics
Y Xu, H Zhu, Y Shen, APM Guttenplan, KL Saar, Y Lu, D Vigolo, LS Itzhaki, TPJ Knowles
MRS Bulletin
(2022)
47
(doi: 10.1557/s43577-022-00279-5)
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
(2022)
(doi: 10.1101/2022.04.07.22273545)
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV‑2
V Denninger, CK Xu, G Meisl, AS Morgunov, S Fiedler, A Ilsley, M Emmenegger, AY Malik, MA Piziorska, MM Schneider, SRA Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS infectious diseases
(2022)
8
(doi: 10.1021/acsinfecdis.1c00486)
An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy
JYL Lam, Y Wu, E Dimou, Z Zhang, MR Cheetham, M Körbel, Z Xia, D Klenerman, JSH Danial
Biophysical Reports
(2022)
2
(doi: 10.1016/j.bpr.2022.100044)
Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, T Welsh, T Sneideris, M Schneider, G Invernizzi, T Herling, N Lorenzen, T Knowles
(2022)
(doi: 10.1101/2022.03.07.483238)
Tie-lines reveal interactions driving heteromolecular condensate formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, PS George-Hyslop, T Michaels, T Knowles
(2022)
(doi: 10.1101/2022.02.22.481401)
The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.
CK Xu, M Castellana-Cruz, SW Chen, Z Du, G Meisl, A Levin, B Mannini, LS Itzhaki, TPJ Knowles, CM Dobson, N Cremades, JR Kumita
Molecules (Basel, Switzerland)
(2022)
27
(doi: 10.3390/molecules27041293)
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
A Farzadfard, JN Pedersen, G Meisl, AK Somavarapu, P Alam, L Goksøyr, MA Nielsen, AF Sander, TPJ Knowles, JS Pedersen, DE Otzen
Communications Biology
(2022)
5
(doi: 10.1038/s42003-022-03059-8)
Multiphase condensates from a kinetically arrested phase transition
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.09.479538)
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
S Fiedler, S Devenish, A Morgunov, A Ilsley, F Ricci, M Emmenegger, V Kosmoliaptsis, E Theel, J Mills, A Sholukh, A Aguzzi, A Iwasaki, A Lynn, T Knowles
(2022)
(doi: 10.1101/2022.02.03.478946)
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
ACS Applied Nano Materials
(2022)
5
(doi: 10.1021/acsanm.1c03691)
2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
ACS Applied Nano Materials
(2022)
5
(doi: 10.1021/acsanm.1c03691)
Phase separating RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, T Welsh, L Vogel, R Kühnemuth, A Majumdar, G Krainer, T Franzmann, S Alberti, C Seidel, TPJ Knowles, A Hyman, R Pappu
(2022)
(doi: 10.1101/2022.02.03.478969)
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.2608)
Rate‐limiting processes of tau aggregate accumulation in Alzheimer's disease
G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman
Alzheimer's & Dementia
(2022)
17
(doi: 10.1002/alz.051680)
Yusuf Hamied Department of Chemistry
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