Centre for Experimental Biophysical Chemistry

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  • Currently displaying 241 - 260 of 1210 publications
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Author Correction: Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging (Nature Protocols, (2022), 17, 11, (2570-2619), 10.1038/s41596-022-00730-6)
JSH Danial, JYL Lam, Y Wu, M Woolley, E Dimou, MR Cheetham, D Emin, D Klenerman
Nature Protocols
(2023)
18
(doi: 10.1038/s41596-023-00909-5)
Pharmacological inhibition of α-synuclein aggregation within liquid condensates
M Vendruscolo, S Dada, Z Toprakcioglu, M Hardenberg, M Cali, L Mrugalla, O Morris, A Roentgen, T Knowles
(2023)
(doi: 10.21203/rs.3.rs-3174399/v1)
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions
M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
(2023)
(doi: 10.21203/rs.3.rs-3252197/v1)
Ganglioside Lipids Inhibit the Aggregation of the Alzheimer’s Related Peptide Amyloid-β
Z Toprakcioglu, AK Jayaram, TPJ Knowles
(2023)
(doi: 10.1101/2023.09.10.556751)
Effects of Processing-Induced Contamination on Organic Electronic Devices.
D Simatos, IE Jacobs, I Dobryden, M Nguyen, A Savva, D Venkateshvaran, M Nikolka, J Charmet, LJ Spalek, M Gicevičius, Y Zhang, G Schweicher, DJ Howe, S Ursel, J Armitage, IB Dimov, U Kraft, W Zhang, M Alsufyani, I McCulloch, RM Owens, PM Claesson, TPJ Knowles, H Sirringhaus
Small methods
(2023)
7
(doi: 10.1002/smtd.202300476)
Thermodynamic profiles for co-translational trigger factor function
TW Herling, AME Cassaignau, AS Wentink, QAE Peter, PC Kumar, T Kartanas, MM Schneider, LD Cabrita, J Christodoulou, TPJ Knowles
(2023)
(doi: 10.1101/2023.08.23.554456)
Glutamate helps unmask the differences in driving forces for phase separation versus clustering of FET family proteins in sub-saturated solutions.
M Kar, LT Vogel, G Chauhan, H Ausserwöger, TJ Welsh, AR Kamath, TPJ Knowles, AA Hyman, CAM Seidel, RV Pappu
(2023)
(doi: 10.1101/2023.08.11.552963)
Electrophysiological In Vitro Study of Long-Range Signal Transmission by Astrocytic Networks.
N Hastings, Y-L Yu, B Huang, S Middya, M Inaoka, NA Erkamp, RJ Mason, A Carnicer-Lombarte, S Rahman, TPJ Knowles, M Bance, GG Malliaras, MRN Kotter
Adv Sci (Weinh)
(2023)
10
(doi: 10.1002/advs.202301756)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, F-U Hartl, SF Lee, TPJ Knowles
(2023)
(doi: 10.1101/2023.07.12.548675)
Self-replication of Aβ42aggregates occurs on small and isolated fibril sites
S Curk, J Krausser, G Meisl, D Frenkel, S Linse, TCT Michaels, TPJ Knowles, A Šarić
(2023)
(doi: 10.1101/2023.07.05.547777)
Super-resolution imaging unveils the self-replication of tau aggregates upon seeding.
E Dimou, T Katsinelos, G Meisl, BJ Tuck, S Keeling, AE Smith, E Hidari, JYL Lam, M Burke, S Lövestam, RT Ranasinghe, WA McEwan, D Klenerman
Cell Rep
(2023)
42
(doi: 10.1016/j.celrep.2023.112725)
Amyloid formation as a protein phase transition
TCT Michaels, D Qian, A Šarić, M Vendruscolo, S Linse, TPJ Knowles
Nature Reviews Physics
(2023)
5
(doi: 10.1038/s42254-023-00598-9)
Amyloids and protein aggregation
S Linse, T Knowles
Chem Sci
(2023)
14
(doi: 10.1039/d2sc90225g)
Positional influence on cellular transcriptional identity revealed through spatially segmented single-cell transcriptomics.
DB Morse, AM Michalowski, M Ceribelli, J De Jonghe, M Vias, D Riley, T Davies-Hill, T Voss, S Pittaluga, C Muus, J Liu, S Boyle, DA Weitz, JD Brenton, JD Buenrostro, TPJ Knowles, CJ Thomas
Cell Systems
(2023)
14
(doi: 10.1016/j.cels.2023.05.003)
Formation of Protein Nanoparticles in Microdroplet Flow Reactors.
Q Zhang, Z Toprakcioglu, AK Jayaram, G Guo, X Wang, TPJ Knowles
ACS Nano
(2023)
17
(doi: 10.1021/acsnano.3c00107)
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
Journal of Infectious Diseases
(2023)
228
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, TJ Welsh, T Sneideris, TM Franzmann, S Qamar, NA Erkamp, J Nixon-Abell, M Kar, P St George-Hyslop, AA Hyman, S Alberti, RV Pappu, TPJ Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
α-Synuclein oligomers form by secondary nucleation
CK Xu, G Meisl, E Andrzejewska, G Krainer, AJ Dear, MC Cruz, S Turi, R Jacquat, WE Arter, M Vendruscolo, S Linse, TP Knowles
(2023)
(doi: 10.1101/2023.05.28.542651)
Label-free detection of proteins with optofluidic hollow-core photonic crystal fibre sensors
JR Heck, E Miele, R Mouthaan, MH Frosz, TPJ Knowles, TG Euser
SPIE Future Sensing Technologies 2023
(2023)
12327
(doi: 10.1117/12.2643905)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
Proceedings of the National Academy of Sciences of USA
(2023)
120
(doi: 10.1073/pnas.2216234120)
Yusuf Hamied Department of Chemistry
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