Centre for Experimental Biophysical Chemistry

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  • Currently displaying 321 - 340 of 1210 publications
Author(s)
Publication title
Journal Name
Publication year
Uncovering the universality of self-replication in protein aggregation and its link to disease.
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
Science advances
(2022)
8
(doi: 10.1126/sciadv.abn6831)
A conformational switch controlling the toxicity of the prion protein.
K Frontzek, M Bardelli, A Senatore, A Henzi, RR Reimann, S Bedir, M Marino, R Hussain, S Jurt, G Meisl, M Pedotti, F Mazzola, G Siligardi, O Zerbe, M Losa, T Knowles, A Lakkaraju, C Zhu, P Schwarz, S Hornemann, MG Holt, L Simonelli, L Varani, A Aguzzi
Nature Structural & Molecular Biology
(2022)
29
(doi: 10.1038/s41594-022-00814-7)
Adsorption free energy predicts amyloid protein nucleation rates
Z Toprakcioglu, A Kamada, TCT Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, TPJ Knowles
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2109718119)
Enhanced surface nano-analytics of transient biomolecular processes
A Miller, S Chia, Z Toprakcioglu, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, TPJ Knowles
(2022)
(doi: 10.1101/2022.07.25.501379)
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, G Meisl, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
iScience
(2022)
25
(doi: 10.1016/j.isci.2022.104766)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
ACS applied bio materials
(2022)
5
(doi: 10.1021/acsabm.2c00225)
Structure specific amyloid precipitation in biofluids
M Rodrigues, P Bhattacharjee, A Brinkmalm, DT Do, CM Pearson, S De, A Ponjavic, JA Varela, K Kulenkampff, I Baudrexel, D Emin, FS Ruggeri, JE Lee, AR Carr, TPJ Knowles, H Zetterberg, TN Snaddon, S Gandhi, SF Lee, D Klenerman
Nature chemistry
(2022)
14
(doi: 10.1038/s41557-022-00976-3)
Phase-separating RNA-binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, TJ Welsh, LT Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
Proc Natl Acad Sci U S A
(2022)
119
(doi: 10.1073/pnas.2202222119)
Recent Advances in Microgels: From Biomolecules to Functionality.
Y Xu, H Zhu, A Denduluri, Y Ou, NA Erkamp, R Qi, Y Shen, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2022)
18
(doi: 10.1002/smll.202200180)
Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease.
G Meisl, TPJ Knowles, D Klenerman
Front Neurosci
(2022)
16
(doi: 10.3389/fnins.2022.909861)
Aging can transform single-component protein condensates into multiphase architectures.
A Garaizar, JR Espinosa, JA Joseph, G Krainer, Y Shen, TPJ Knowles, R Collepardo-Guevara
Proceedings of the National Academy of Sciences
(2022)
119
(doi: 10.1073/pnas.2119800119)
Uncovering the universality of self-replication in protein aggregation and its link to disease
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
(2022)
(doi: 10.1101/2022.06.08.495339)
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses
JX Meng, Y Zhang, D Saman, AM Haider, S De, JC Sang, K Brown, K Jiang, J Humphrey, L Julian, E Hidari, SF Lee, G Balmus, RA Floto, C Bryant, JLP Benesch, Y Ye, D Klenerman
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-30461-x)
Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates
Z Toprakcioglu, A Kamada, T Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, T Knowles
(2022)
(doi: 10.26434/chemrxiv-2022-tjrtf)
Bioprinting microporous functional living materials from protein-based core-shell microgels
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
(2022)
(doi: 10.1101/2022.05.03.490444)
Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers
TCT Michaels, AJ Dear, SIA Cohen, M Vendruscolo, TPJ Knowles
The Journal of chemical physics
(2022)
156
(doi: 10.1063/5.0077609)
Analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
(2022)
(doi: 10.1101/2022.04.23.489256)
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic
R Limbocker, S Errico, D Barbut, TPJ Knowles, M Vendruscolo, F Chiti, M Zasloff
Natural Product Reports: a journal of current development in bioorganic chemistry
(2022)
39
(doi: 10.1039/d1np00042j)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation
KN Baumann, M Sanguanini, O Rimon, G Šneiderienė, H Greer, D Thacker, M Schneider, S Linse, TPJ Knowles, M Vendruscolo
(2022)
(doi: 10.1101/2022.04.16.488542)
resPAINT: Accelerating volumetric super-resolution localisation microscopy by active control of probe emission
EW Sanders, AR Carr, E Bruggeman, M Koerbel, SI Benaissa, RF Donat, AM Santos, J McColl, K O’Holleran, D Klenerman, SJ Davis, SF Lee, A Ponjavic
(2022)
(doi: 10.1101/2022.04.14.488333)
Yusuf Hamied Department of Chemistry
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