Centre for Experimental Biophysical Chemistry

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  • Currently displaying 321 - 340 of 1199 publications
Author(s)
Publication title
Journal Name
Publication year
Uncovering the universality of self-replication in protein aggregation and its link to disease
G Meisl, CK Xu, JD Taylor, TCT Michaels, A Levin, D Otzen, D Klenerman, S Matthews, S Linse, M Andreasen, TPJ Knowles
(2022)
(doi: 10.1101/2022.06.08.495339)
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses
JX Meng, Y Zhang, D Saman, AM Haider, S De, JC Sang, K Brown, K Jiang, J Humphrey, L Julian, E Hidari, SF Lee, G Balmus, RA Floto, C Bryant, JLP Benesch, Y Ye, D Klenerman
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-30461-x)
Adsorption Free Energy Predicts Amyloid Protein Nucleation Rates
Z Toprakcioglu, A Kamada, T Michaels, M Xie, J Krausser, J Wei, A Saric, M Vendruscolo, T Knowles
(2022)
(doi: 10.26434/chemrxiv-2022-tjrtf)
Bioprinting microporous functional living materials from protein-based core-shell microgels
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
(2022)
(doi: 10.1101/2022.05.03.490444)
Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers
TCT Michaels, AJ Dear, SIA Cohen, M Vendruscolo, TPJ Knowles
Journal of Chemical Physics
(2022)
156
(doi: 10.1063/5.0077609)
Analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
(2022)
(doi: 10.1101/2022.04.23.489256)
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic.
R Limbocker, S Errico, D Barbut, TPJ Knowles, M Vendruscolo, F Chiti, M Zasloff
Natural Product Reports: a journal of current development in bioorganic chemistry
(2022)
39
(doi: 10.1039/d1np00042j)
A Kinetic Map of the Influence of Biomimetic Lipid Membrane Models on Aβ42 Aggregation
KN Baumann, M Sanguanini, O Rimon, G Šneiderienė, H Greer, D Thacker, M Schneider, S Linse, TPJ Knowles, M Vendruscolo
(2022)
(doi: 10.1101/2022.04.16.488542)
resPAINT: Accelerating volumetric super-resolution localisation microscopy by active control of probe emission
EW Sanders, AR Carr, E Bruggeman, M Koerbel, SI Benaissa, RF Donat, AM Santos, J McColl, K O’Holleran, D Klenerman, SJ Davis, SF Lee, A Ponjavic
(2022)
(doi: 10.1101/2022.04.14.488333)
Micromechanics of soft materials using microfluidics
Y Xu, H Zhu, Y Shen, APM Guttenplan, KL Saar, Y Lu, D Vigolo, LS Itzhaki, TPJ Knowles
MRS Bulletin
(2022)
47
(doi: 10.1557/s43577-022-00279-5)
Both COVID-19 infection and vaccination induce high-affinity cross-clade responses to SARS-CoV-2 variants
M Emmenegger, S Fiedler, SD Brugger, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, AY Malik, T Scheier, L Batkitar, L Madrigal, M Rossi, AK Lynn, L Saleh, A von Eckardstein, TPJ Knowles, A Aguzzi
(2022)
(doi: 10.1101/2022.04.07.22273545)
Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV‑2
V Denninger, CK Xu, G Meisl, AS Morgunov, S Fiedler, A Ilsley, M Emmenegger, AY Malik, MA Piziorska, MM Schneider, SRA Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS Infect Dis
(2022)
8
(doi: 10.1021/acsinfecdis.1c00486)
An economic, square-shaped flat-field illumination module for TIRF-based super-resolution microscopy
JYL Lam, Y Wu, E Dimou, Z Zhang, MR Cheetham, M Körbel, Z Xia, D Klenerman, JSH Danial
Biophysical reports
(2022)
2
(doi: 10.1016/j.bpr.2022.100044)
Surface interaction patches link non-specific binding and phase separation of antibodies
H Ausserwöger, G Krainer, TJ Welsh, T Sneideris, MM Schneider, G Invernizzi, TW Herling, N Lorenzen, TPJ Knowles
(2022)
(doi: 10.1101/2022.03.07.483238)
Tie-lines reveal interactions driving heteromolecular condensate formation
D Qian, TJ Welsh, NA Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, TCT Michaels, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.22.481401)
The C-terminal tail of α-synuclein protects against aggregate replication but is critical for oligomerization.
A Farzadfard, JN Pedersen, G Meisl, AK Somavarapu, P Alam, L Goksøyr, MA Nielsen, AF Sander, TPJ Knowles, JS Pedersen, DE Otzen
Communications Biology
(2022)
5
(doi: 10.1038/s42003-022-03059-8)
Multiphase condensates from a kinetically arrested phase transition
NA Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, P St George-Hyslop, JD Schmit, DA Weitz, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.09.479538)
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
S Fiedler, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, M Emmenegger, V Kosmoliaptsis, ES Theel, JR Mills, AM Sholukh, A Aguzzi, A Iwasaki, AK Lynn, TPJ Knowles
(2022)
(doi: 10.1101/2022.02.03.478946)
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of Single Macromolecules and Colloids in Solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, PK Challa, Q Peter, Z Toprakcioglu, CK Xu, UF Keyser, JJ Baumberg, CF Kaminski, TPJ Knowles
ACS Applied Nano Materials
(2022)
5
(doi: 10.1021/acsanm.1c03691)
Phase separating RNA binding proteins form heterogeneous distributions of clusters in subsaturated solutions
M Kar, F Dar, TJ Welsh, L Vogel, R Kühnemuth, A Majumdar, G Krainer, TM Franzmann, S Alberti, CAM Seidel, TPJ Knowles, AA Hyman, RV Pappu
(2022)
(doi: 10.1101/2022.02.03.478969)
Yusuf Hamied Department of Chemistry
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