Centre for Experimental Biophysical Chemistry

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  • Currently displaying 321 - 340 of 1270 publications
Author(s)
Publication title
Journal Name
Publication year
Surface patches induce nonspecific binding and phase separation of antibodies.
H Ausserwöger, G Krainer, TJ Welsh, N Thorsteinson, E de Csilléry, T Sneideris, MM Schneider, T Egebjerg, G Invernizzi, TW Herling, N Lorenzen, TPJ Knowles
Proc Natl Acad Sci U S A
(2023)
120
(doi: 10.1073/pnas.2210332120)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
bioRxiv
(2023)
(doi: 10.1101/2023.03.22.533832)
The central role of microvilli in shaping T-cell responses
D Klenerman
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-36855-9)
α-synuclein oligomers displace monomeric α-synuclein from lipid membranes
G Šneiderienė, MA Czekalska, CK Xu, A Jayaram, G Krainer, WE Arter, Q Peter, M Castellana-Cruz, KL Saar, A Levin, T Mueller, S Fiedler, SRA Devenish, H Fiegler, JR Kumita, TPJ Knowles
(2023)
(doi: 10.1101/2023.03.21.533646)
Multidimensional Protein Solubility Optimization with an Ultrahigh- Throughput Microfluidic Platform
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
Anal Chem
(2023)
95
(doi: 10.1021/acs.analchem.2c05495)
Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly.
A Kamada, Z Toprakcioglu, TPJ Knowles
Biomacromolecules
(2023)
24
(doi: 10.1021/acs.biomac.2c01479)
Modulating Nucleic Acid Phase Transitions as a Mechanism of Action for Cell-Penetrating Antimicrobial Peptides
T Sneideris, NA Erkamp, H Ausserwöger, KL Saar, TJ Welsh, D Qian, MLLY Johncock, G Krainer, A Borodavka, TPJ Knowles
(2023)
(doi: 10.1101/2023.03.11.532143)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
Biosensors & bioelectronics
(2023)
228
(doi: 10.1016/j.bios.2023.115196)
Single-Molecule Sizing through Nanocavity Confinement.
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
Nano Letters
(2023)
23
(doi: 10.1021/acs.nanolett.1c04830)
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
ST Dada, MC Hardenberg, Z Toprakcioglu, LK Mrugalla, MP Cali, MO McKeon, E Klimont, TCT Michaels, TPJ Knowles, M Vendruscolo
Proc Natl Acad Sci U S A
(2023)
120
(doi: 10.1073/pnas.2208792120)
Selenium Silk Nanostructured Films with Antifungal and Antibacterial Activity.
Z Toprakcioglu, EG Wiita, AK Jayaram, RC Gregory, TPJ Knowles
ACS Applied Materials & Interfaces
(2023)
15
(doi: 10.1021/acsami.2c21013)
Non-specificity fingerprints for clinical stage antibodies in solution
TW Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, TPJ Knowles
(2023)
(doi: 10.1101/2023.02.13.528263)
Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling
M Emmenegger, R Worth, S Fiedler, SRA Devenish, TPJ Knowles, A Aguzzi
STAR Protoc
(2023)
4
(doi: 10.1016/j.xpro.2023.102095)
Characterizing protein interactions in biomolecular phase separation
H Ausserwöger, G Krainer, D Qian, T Welsh, T Sneideris, MM Schneider, G Invernizzi, TW Herling, N Lorenzen, TP Knowles
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.963)
Designer proteins as potential therapeutic biomolecular condensates
TLC Ng, M Hoare, T Welsh, S Tomas, E Wilde, TPJ Knowles, LS Itzhaki, JR Kumita
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.568)
Approximate analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.1243)
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O’Holleran, SF Lee
(2023)
(doi: 10.1101/2023.02.07.527479)
Spatially non-uniform condensates emerge from dynamically arrested phase separation
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
Nature communications
(2023)
14
(doi: 10.1038/s41467-023-36059-1)
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
Nature communications
(2023)
14
(doi: 10.1038/s41467-023-35792-x)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y Liao, M Fernandopulle, G Wang, H Choi, L Hao, C Drerup, R Patel, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, N Matthew, M Czekalska, G Musteikyte, M Gachechiladze, C Stephens, H Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
MOLECULAR BIOLOGY OF THE CELL
(2023)
34
Yusuf Hamied Department of Chemistry
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