Centre for Experimental Biophysical Chemistry

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  • Currently displaying 301 - 320 of 1122 publications
Author(s)
Publication title
Journal Name
Publication year
Alpha Synuclein only Forms Fibrils In Vitro when Larger than its Critical Size of 70 Monomers.
SE Sanchez, DR Whiten, G Meisl, FS Ruggeri, E Hidari, D Klenerman
ChemBioChem
(2021)
22
(doi: 10.1002/cbic.202100285)
Unraveling the Physicochemical Determinants of Protein Liquid-liquid Phase Separation by Nanoscale Infrared Vibrational Spectroscopy.
FS Ruggeri, AM Miller, M Vendruscolo, TPJ Knowles
Bio Protoc
(2021)
11
(doi: 10.21769/bioprotoc.4122)
Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson's disease.
E Lobanova, D Whiten, FS Ruggeri, CG Taylor, A Kouli, Z Xia, D Emin, YP Zhang, JYL Lam, CH Williams-Gray, D Klenerman
Brain: a journal of neurology
(2021)
145
(doi: 10.1093/brain/awab306)
Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels (Adv. Mater. 33/2021)
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202170258)
Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation
J Wen, L Hong, G Krainer, Q-Q Yao, TPJ Knowles, S Wu, S Perrett
J Am Chem Soc
(2021)
143
(doi: 10.1021/jacs.1c03078)
Feedback control of protein aggregation.
AJ Dear, TCT Michaels, TPJ Knowles, L Mahadevan
J Chem Phys
(2021)
155
(doi: 10.1063/5.0055925)
Quantum Emitter Localisation in Layer-Engineered Hexagonal Boron Nitride
JC Stewart, Y Fan, JSH Danial, A Goetz, AS Prasad, OJ Burton, JA Alexander-Webber, SF Lee, SM Skoff, V Babenko, S Hofmann
ACS nano
(2021)
15
(doi: 10.1021/acsnano.1c04467)
Noncontact Nanoscale Imaging of Cells
D Klenerman, Y Korchev, P Novak, A Shevchuk
Annual review of analytical chemistry (Palo Alto, Calif.)
(2021)
14
(doi: 10.1146/annurev-anchem-091420-120101)
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
S Fiedler, V Denninger, A Morgunov, A Ilsley, R Worth, G Meisl, C Xu, M Piziorska, F Ricci, A Malik, S Devenish, M Schneider, V Kosmoliaptsis, A Aguzzi, A Iwasaki, H Fiegler, T Knowles
(2021)
(doi: 10.1101/2021.07.23.453327)
LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
EMBO molecular medicine
(2021)
13
(doi: 10.15252/emmm.202114745)
Understanding the role of memory re-activation and cross-reactivity in the defense against SARS-CoV-2
V Denninger, C Xu, G Meisl, A Morgunov, S Fiedler, A Ilsley, M Emmenegger, A Malik, M Piziorska, M Schneider, S Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, T Knowles
(2021)
(doi: 10.1101/2021.07.23.453352)
The unhappy chaperone
S Linse, K Thalberg, TPJ Knowles
QRB discovery
(2021)
2
(doi: 10.1017/qrd.2021.5)
Liquid–Liquid Phase-Separated Systems from Reversible Gel–Sol Transition of Protein Microgels
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced materials (Deerfield Beach, Fla.)
(2021)
33
(doi: 10.1002/adma.202008670)
Protein Conjugation by Electrophilic Alkynylation Using 5-(Alkynyl)dibenzothiophenium Triflates.
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjugate chemistry
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in bioelectronic sensing.
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends in biotechnology
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer's disease.
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, R Cascella, A Bigi, LR Sasser, NR Block, AK Wright, RP Kreiser, ET Custy, G Meisl, S Errico, J Habchi, P Flagmeier, T Kartanas, JE Hollows, LT Nguyen, K LeForte, D Barbut, JR Kumita, C Cecchi, M Zasloff, TPJ Knowles, CM Dobson, F Chiti, M Vendruscolo
Front Neurosci
(2021)
15
(doi: 10.3389/fnins.2021.680026)
Machine learning-aided protein identification from multidimensional signatures
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
Lab Chip
(2021)
21
(doi: 10.1039/d0lc01148g)
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nature Communications
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Mapping the binding site topology of amyloid protein aggregates using multivalent ligands
E Sanna, M Rodrigues, SG Fagan, TS Chisholm, K Kulenkampff, D Klenerman, MG Spillantini, FI Aigbirhio, CA Hunter
Chemical Science
(2021)
12
(doi: 10.1039/d1sc01263k)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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