Centre for Experimental Biophysical Chemistry

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  • Currently displaying 261 - 280 of 1122 publications
Author(s)
Publication title
Journal Name
Publication year
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.2608)
Rate‐limiting processes of tau aggregate accumulation in Alzheimer's disease
G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman
Alzheimer's & Dementia
(2022)
17
(doi: 10.1002/alz.051680)
Using microscopy techniques to structurally characterise TDP-43 inclusions present in mammalian cell models
NS Matharu, CW Chung, JR Kumita, GS Kaminski, TP Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1401)
Imaging T-cell activation: topography and features of early T-cell contacts
M Korbel, E Jenkins, JT McColl, C O'Brien-Ball, AH Lippert, AM Santos, SF Lee, SJ Davis, D Klenerman
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.1976)
Mechanism of secondary nucleation from the direct observation of Aβ42 aggregation at the single fibril level
MR Zimmermann, SC Bera, G Meisl, S Dasadhikari, S Ghosh, S Linse, K Garai, TPJ Knowles
Biophysical Journal
(2022)
121
(doi: 10.1016/j.bpj.2021.11.556)
Simpler and faster quartz crystal microbalance for macromolecule detection using fixed frequency drive
A Guha, N Sandström, VP Ostanin, D Klenerman, SK Ghosh
Sensors and Actuators B Chemical
(2022)
358
(doi: 10.1016/j.snb.2022.131442)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g-v2)
DNA-Liposome Hybrid Carriers for Triggered Cargo Release
KN Baumann, T Schröder, PS Ciryam, D Morzy, P Tinnefeld, TPJ Knowles, S Hernández-Ainsa
(2022)
(doi: 10.26434/chemrxiv-2022-x731g)
Surface Electrostatics Govern the Emulsion Stability of Biomolecular Condensates.
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
Nano Lett
(2022)
22
(doi: 10.1021/acs.nanolett.1c03138)
Improving safety in regional anaesthesia with a novel, yet simple intervention. A staff survey of the impact of the intervention
R Thomas, S Jigajinni, S Green, T Knowles, R McCartney, A Williams
ANAESTHESIA
(2022)
77
Microchip Free-Flow Electrophoresis for Bioanalysis, Sensing, and Purification
WE Arter, KL Saar, TW Herling, TPJ Knowles
(2022)
2394
(doi: 10.1007/978-1-0716-1811-0_16)
Thermodynamics of oligomeric alph-asynuclein-membrane interactions
G Musteikyte, C Xu, M Czekalska, Q Peter, G Krainer, S Devenish, T Knowles
FEBS OPEN BIO
(2022)
12
Universal lab-on-a-chip microfluidic spray deposition for bulk and single-molecule analytical methods on surfaces
AM Miller, SKR Chia, T Hakala, Z Toprakcioglu, M Vendruscolo, FS Ruggeri, TPJ Knowles
BIOPHYSICAL JOURNAL
(2022)
121
A Comparative Study of High-Contrast Fluorescence Lifetime Probes for Imaging Amyloid in Tissue.
F Gorka, CM Pearson, E Bulovaite, YP Zhang, A Handa, SGN Grant, TN Snaddon, LM Needham, SF Lee
The Journal of Physical Chemistry B: Biophysical Chemistry, Biomaterials, Liquids, and Soft Matter
(2021)
125
(doi: 10.1021/acs.jpcb.1c07762)
Single-molecule sizing through nano-cavity confinement
R Jacquat, G Krainer, Q Peter, AN Babar, O Vanderpoorten, C Xu, T Welsh, C Kaminski, U Keyser, J Baumberg, T Knowles
(2021)
(doi: 10.1101/2021.12.13.472369)
Structure-based discovery of small molecule inhibitors of the autocatalytic proliferation of α-synuclein aggregates
S Chia, ZF Brotzakis, RI Horne, A Possenti, B Mannini, R Cataldi, M Nowinska, R Staats, S Linse, TPJ Knowles, J Habchi, M Vendruscolo
(2021)
(doi: 10.1101/2021.12.05.471256)
Microfluidic characterisation reveals broad range of SARS-CoV-2 antibody affinity in human plasma
MM Schneider, M Emmenegger, CK Xu, I Condado Morales, G Meisl, P Turelli, C Zografou, MR Zimmermann, BM Frey, S Fiedler, V Denninger, RP Jacquat, L Madrigal, A Ilsley, V Kosmoliaptsis, H Fiegler, D Trono, TP Knowles, A Aguzzi
Life Sci Alliance
(2021)
5
(doi: 10.26508/lsa.202101270)
2-photon-fabricated nano-fluidic traps for extended detection of single macromolecules and colloids in solution
O Vanderpoorten, AN Babar, G Krainer, RPB Jacquat, P Challa, Q Peter, Z Toprakcioglu, C Xu, U Keyser, J Baumberg, C Kaminski, T Knowles
(2021)
(doi: 10.1101/2021.11.17.468989)
Proliferation of Tau 304-380 Fragment Aggregates through Autocatalytic Secondary Nucleation.
DC Rodriguez Camargo, E Sileikis, S Chia, E Axell, K Bernfur, RL Cataldi, SIA Cohen, G Meisl, J Habchi, TPJ Knowles, M Vendruscolo, S Linse
ACS Chem Neurosci
(2021)
12
(doi: 10.1021/acschemneuro.1c00454)
Discovery of Potent Inhibitors of α-Synuclein Aggregation Using Structure-Based Iterative Learning
R Horne, E Andrzejewska, P Alam, F Brotzakis, A Srivastava, A Aubert, M Nowinska, R Gregory, R Staats, A Possenti, S Chia, P Sormanni, B Ghetti, B Caughey, T Knowles, M Vendruscolo
(2021)
(doi: 10.1101/2021.11.10.468009)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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