Centre for Experimental Biophysical Chemistry

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  • Currently displaying 341 - 360 of 1108 publications
Author(s)
Publication title
Journal Name
Publication year
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et Biophysica Acta (BBA) - Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress.
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter.
R Staats, TCT Michaels, P Flagmeier, S Chia, RI Horne, J Habchi, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Communications Chemistry
(2020)
3
(doi: 10.1038/s42004-020-00412-y)
Physical mechanisms of amyloid nucleation on fluid membranes.
J Krausser, TPJ Knowles, A Šarić
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.2007694117)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions (vol 16, pg 3586, 2020)
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernardes, TPJ Knowles
Soft Matter
(2020)
17
(doi: 10.1039/d0sm90246b)
New solution for fast axial scanning in fluorescence microscopy
W Zong
Light: Science & Applications
(2020)
9
(doi: 10.1038/s41377-020-00442-0)
Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals
J Adamcik, FS Ruggeri, JT Berryman, A Zhang, TPJ Knowles, R Mezzenga
Advanced Science
(2020)
8
(doi: 10.1002/advs.202002182)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
A Vilalta, Y Zhou, J Sevalle, J Griffin, K Satoh, D Allendorf, S De, M Puigdellívol, A Bruzas, M Burguillos, R Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, P Fraser, D Klenerman, S Lee, P St George-Hyslop, G Brown
(2020)
(doi: 10.1101/2020.12.03.409995)
Soft Polydimethylsiloxane-Supported Lipid Bilayers for Studying T Cell Interactions
AH Lippert, IB Dimov, AK Winkel, J Humphrey, J McColl, KY Chen, AM Santos, E Jenkins, K Franze, SJ Davis, D Klenerman
Biophysical Journal
(2020)
120
(doi: 10.1016/j.bpj.2020.11.021)
Machine learning aided top-down proteomics on a microfluidic platform
Y Zhang, M Wright, K Saar, P Challa, A Morgunov, Q Peter, S Devenish, C Dobson, TPJ Knowles
(2020)
(doi: 10.1101/2020.11.14.381376)
On the Mechanism of Self-Assembly by a Hydrogel-Forming Peptide
GA Braun, BE Ary, AJ Dear, MCH Rohn, AM Payson, DSM Lee, RC Parry, C Friedman, TPJ Knowles, S Linse, KS Åkerfeldt
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.0c00989)
Amyloid precipitation in biofluids using a structure-specific chemical antibody
M Rodrigues, P Bhattacharjee, A Brinkmalm, D Do, C Pearson, S De, A Ponjavic, J Varela, F Ruggeri, I Baudrexel, J Lee, A Carr, K Kulenkampff, T Knowles, H Zetterberg, T Snaddon, S Gandhi, S Lee, D Klenerman
(2020)
(doi: 10.21203/rs.3.rs-81521/v1)
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer's disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, IC Felli, R Pierattelli, TPJ Knowles, CM Dobson, M Vendruscolo
Science advances
(2020)
6
(doi: 10.1126/SCIADV.ABB5924)
Machine learning models for predicting protein condensate formation from sequence determinants and embeddings
K Saar, A Morgunov, R Qi, W Arter, G Krainer, A Lee, T Knowles
(2020)
(doi: 10.1101/2020.10.26.354753)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, F Kirchhoff, T Knowles, FS Ruggeri, C Synatschke, J Münch, T Weil
(2020)
(doi: 10.26434/chemrxiv.13129709)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, F Kirchhoff, T Knowles, FS Ruggeri, C Synatschke, J Münch, T Weil
(2020)
(doi: 10.26434/chemrxiv.13129709.v1)
Microscale diffusiophoresis of proteins
Q Peter, R Jacquat, T Herling, P Challa, T Kartanas, T Knowles
(2020)
(doi: 10.21203/rs.3.rs-90645/v1)
Rapid structural, kinetic, and immunochemical analysis of alpha-synuclein oligomers in solution
WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles
Nano letters
(2020)
20
(doi: 10.1021/acs.nanolett.0c03260)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation (vol 27, pg 2781, 2020)
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell Death & Differentiation
(2020)
28
(doi: 10.1038/s41418-020-00634-6)
vLUME: 3D virtual reality for single-molecule localization microscopy
S Lee, A Handa, L-M Needham, A Carr, A Ponjavic, J McColl
Nat Methods
(2020)
17
(doi: 10.1038/s41592-020-0962-1)
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