Centre for Experimental Biophysical Chemistry

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 361 - 380 of 1158 publications
Author(s)
Publication title
Journal Name
Publication year
DeepSinse: deep learning-based detection of single molecules.
JSH Danial, R Shalaby, K Cosentino, MM Mahmoud, F Medhat, D Klenerman, AJ Garcia Saez
Bioinformatics
(2021)
37
(doi: 10.1093/bioinformatics/btab352)
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Rapid highly sensitive general protein quantification through on-chip chemiluminescence.
HK Chiu, T Kartanas, KL Saar, CM Luxhøj, S Devenish, TPJ Knowles
Biomicrofluidics
(2021)
15
(doi: 10.1063/5.0039872)
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
(2021)
(doi: 10.1101/2021.04.25.441302)
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS Infectious Diseases
(2021)
7
(doi: 10.1021/acsinfecdis.1c00047)
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent inflammatory responses
D Klenerman, J Meng, Y Zhang, D Saman, S De, J Sang, K Jiang, J Humphrey, L Julian, E Hidari, RA Floto, S Lee, C Bryant, J Benesch, Y Ye
(2021)
(doi: 10.21203/rs.3.rs-374549/v1)
Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering.
BJ Eves, JJ Doutch, AE Terry, H Yin, M Moulin, M Haertlein, VT Forsyth, P Flagmeier, TPJ Knowles, DM Dias, G Lotze, AM Seddon, AM Squires
RSC chemical biology
(2021)
2
(doi: 10.1039/d1cb00001b)
Learning the molecular grammar of protein condensates from sequence determinants and embeddings.
KL Saar, AS Morgunov, R Qi, WE Arter, G Krainer, AA Lee, TPJ Knowles
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2019053118)
Tau AD fragment aggregates proliferate through autocatalytic secondary nucleation
DR Camargo, E Sileikis, S Chia, E Axell, K Bernfur, R Cataldi, S Cohen, G Meisl, J Habchi, T Knowles, M Vendruscolo, S Linse
(2021)
(doi: 10.21203/rs.3.rs-351489/v1)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer’s R47H mutant increases Aβ aggregation
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
The Journal of biological chemistry
(2021)
296
(doi: 10.1016/j.jbc.2021.100631)
Scaling analysis reveals the mechanism and rates of prion replication in vivo
G Meisl, T Kurt, I Condado-Morales, C Bett, S Sorce, M Nuvolone, TCT Michaels, D Heinzer, M Avar, SIA Cohen, S Hornemann, A Aguzzi, CM Dobson, CJ Sigurdson, TPJ Knowles
Nature Structural & Molecular Biology
(2021)
28
(doi: 10.1038/s41594-021-00565-x)
CSPα reduces aggregates and rescues striatal dopamine release in αsynuclein transgenic mice
L Caló, E Hidari, M Wegrzynowicz, JW Dalley, BL Schneider, M Podgajna, O Anichtchik, E Carlson, D Klenerman, MG Spillantini
Brain
(2021)
144
(doi: 10.1093/brain/awab076)
From Protein Building Blocks to Functional Materials.
Y Shen, A Levin, A Kamada, Z Toprakcioglu, M Rodriguez-Garcia, Y Xu, TPJ Knowles
ACS nano
(2021)
15
(doi: 10.1021/acsnano.0c08510)
The role of clearance mechanisms in the kinetics of pathological protein aggregation involved in neurodegenerative diseases
TB Thompson, G Meisl, TPJ Knowles, A Goriely
The Journal of Chemical Physics
(2021)
154
(doi: 10.1063/5.0031650)
Shear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels.
Z Toprakcioglu, TPJ Knowles
Scientific reports
(2021)
11
(doi: 10.1038/s41598-021-85199-1)
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
M Perni, A van der Goot, R Limbocker, TJ van Ham, FA Aprile, CK Xu, P Flagmeier, K Thijssen, P Sormanni, G Fusco, SW Chen, PK Challa, JB Kirkegaard, RF Laine, KY Ma, MBD Müller, T Sinnige, JR Kumita, SIA Cohen, R Seinstra, GS Kaminski Schierle, CF Kaminski, D Barbut, A De Simone, TPJ Knowles, M Zasloff, EAA Nollen, M Vendruscolo, CM Dobson
Front Cell Dev Biol
(2021)
9
(doi: 10.3389/fcell.2021.552549)
Single molecule imaging of protein aggregation in Dementia: Methods, insights and prospects
JSH Danial, D Klenerman
Neurobiology of disease
(2021)
153
(doi: 10.1016/j.nbd.2021.105327)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans.
T Sinnige, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, RI Morimoto
Proceedings of the National Academy of Sciences of the United States of America
(2021)
118
(doi: 10.1073/pnas.2021888118)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, K Kaygisiz, F Kirchhoff, TPJ Knowles, FS Ruggeri, CV Synatschke, J Münch, T Weil
Advanced Functional Materials
(2021)
31
(doi: 10.1002/adfm.202009382)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Nature communications
(2021)
12
(doi: 10.1038/s41467-021-21181-9)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Contact The Centre for Experimental Biophysical Chemistry

Email: biophysicalchemistry@ch.cam.ac.uk

Study at Cambridge

About the University

Research at Cambridge