Centre for Experimental Biophysical Chemistry

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  • Currently displaying 441 - 460 of 1158 publications
Author(s)
Publication title
Journal Name
Publication year
Multidimensional protein characterisation using microfluidic post-column analysis
T Scheidt, T Kartanas, Q Peter, MM Schneider, KL Saar, T Müller, PK Challa, A Levin, S Devenish, TPJ Knowles
Lab Chip
(2020)
20
(doi: 10.1039/d0lc00219d)
Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Aβ42 Oligomers
FS Ruggeri, J Habchi, S Chia, M Vendruscolo, TPJ Knowles
(2020)
(doi: 10.1101/2020.06.24.168997)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
Chemical Science
(2020)
11
(doi: 10.1039/c9sc05905a)
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers.
FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1919464117)
Microfluidic Templating of Spatially Inhomogeneous Protein Microgels.
Y Xu, RPB Jacquat, Y Shen, D Vigolo, D Morse, S Zhang, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2020)
16
(doi: 10.1002/smll.202000432)
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy
FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles
Nature communications
(2020)
11
(doi: 10.1038/s41467-020-16728-1)
Identification of on- and off-pathway oligomers in amyloid fibril formation
AJ Dear, G Meisl, A Šarić, TCT Michaels, M Kjaergaard, S Linse, TPJ Knowles
Chemical science
(2020)
11
(doi: 10.1039/c9sc06501f)
High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles
(2020)
(doi: 10.1101/2020.06.04.132308)
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche
(2020)
(doi: 10.1101/2020.05.26.116400)
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.24.113498)
Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit
WE Arter, Y Yusim, Q Peter, CG Taylor, D Klenerman, UF Keyser, TPJ Knowles
ACS nano
(2020)
14
(doi: 10.1021/acsnano.0c00628)
Single Molecule Light Field Microscopy
RR Sims, SA Rehman, MO Lenz, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
(2020)
(doi: 10.1101/2020.05.20.104802)
Ultrastructural evidence for self-replication of alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Törnquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, A Malmendal, M Akke, S Linse
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.1918481117)
Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform.
M Koopman, Q Peter, RI Seinstra, M Perni, M Vendruscolo, CM Dobson, TPJ Knowles, EAA Nollen
Nature Protocols
(2020)
15
(doi: 10.1038/s41596-020-0321-9)
Kinetic diversity of amyloid oligomers.
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, CM Dobson, TPJ Knowles
Proc Natl Acad Sci U S A
(2020)
117
(doi: 10.1073/pnas.1922267117)
ThX – a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
Chemical science
(2020)
11
(doi: 10.1039/c9sc04730a)
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell death and differentiation
(2020)
27
(doi: 10.1038/s41418-020-0552-x)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.04.076299)
A Microfluidic Co-Flow Route for Human Serum Albumin-Drug-Nanoparticle Assembly.
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
Chemistry - A European Journal
(2020)
26
(doi: 10.1002/chem.202001146)
Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage‐gated calcium channels and NADPH oxidase
N Esteras, F Kundel, GF Amodeo, EV Pavlov, D Klenerman, AY Abramov
The FEBS Journal
(2020)
288
(doi: 10.1111/febs.15340)
Yusuf Hamied Department of Chemistry
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