Centre for Experimental Biophysical Chemistry

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  • Currently displaying 441 - 460 of 1233 publications
Author(s)
Publication title
Journal Name
Publication year
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
(2021)
(doi: 10.1101/2021.04.25.441302)
Antibody Affinity Governs the Inhibition of SARS-CoV-2 Spike/ACE2 Binding in Patient Serum.
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
ACS infectious diseases
(2021)
7
(doi: 10.1021/acsinfecdis.1c00047)
Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent inflammatory responses
D Klenerman, J Meng, Y Zhang, D Saman, S De, J Sang, K Jiang, J Humphrey, L Julian, E Hidari, RA Floto, S Lee, C Bryant, J Benesch, Y Ye
(2021)
(doi: 10.21203/rs.3.rs-374549/v1)
Elongation rate and average length of amyloid fibrils in solution using isotope-labelled small-angle neutron scattering
BJ Eves, JJ Doutch, AE Terry, H Yin, M Moulin, M Haertlein, VT Forsyth, P Flagmeier, TPJ Knowles, DM Dias, G Lotze, AM Seddon, AM Squires
RSC Chem Biol
(2021)
2
(doi: 10.1039/d1cb00001b)
Tau AD fragment aggregates proliferate through autocatalytic secondary nucleation
DR Camargo, E Sileikis, S Chia, E Axell, K Bernfur, R Cataldi, S Cohen, G Meisl, J Habchi, T Knowles, M Vendruscolo, S Linse
(2021)
(doi: 10.21203/rs.3.rs-351489/v1)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer’s R47H mutant increases Aβ aggregation
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
The Journal of biological chemistry
(2021)
296
(doi: 10.1016/j.jbc.2021.100631)
Scaling analysis reveals the mechanism and rates of prion replication in vivo
G Meisl, T Kurt, I Condado-Morales, C Bett, S Sorce, M Nuvolone, TCT Michaels, D Heinzer, M Avar, SIA Cohen, S Hornemann, A Aguzzi, CM Dobson, CJ Sigurdson, TPJ Knowles
Nat Struct Mol Biol
(2021)
28
(doi: 10.1038/s41594-021-00565-x)
The role of clearance mechanisms in the kinetics of pathological protein aggregation involved in neurodegenerative diseases
TB Thompson, G Meisl, TPJ Knowles, A Goriely
J Chem Phys
(2021)
154
(doi: 10.1063/5.0031650)
CSPα reduces aggregates and rescues striatal dopamine release in α-synuclein transgenic mice.
L Caló, E Hidari, M Wegrzynowicz, JW Dalley, BL Schneider, M Podgajna, O Anichtchik, E Carlson, D Klenerman, MG Spillantini
Brain: a journal of neurology
(2021)
144
(doi: 10.1093/brain/awab076)
Shear-mediated sol-gel transition of regenerated silk allows the formation of Janus-like microgels
Z Toprakcioglu, TPJ Knowles
Scientific Reports
(2021)
11
(doi: 10.1038/s41598-021-85199-1)
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
M Perni, A van der Goot, R Limbocker, TJ van Ham, FA Aprile, CK Xu, P Flagmeier, K Thijssen, P Sormanni, G Fusco, SW Chen, PK Challa, JB Kirkegaard, RF Laine, KY Ma, MBD Müller, T Sinnige, JR Kumita, SIA Cohen, R Seinstra, GS Kaminski Schierle, CF Kaminski, D Barbut, A De Simone, TPJ Knowles, M Zasloff, EAA Nollen, M Vendruscolo, CM Dobson
Frontiers in cell and developmental biology
(2021)
9
(doi: 10.3389/fcell.2021.552549)
Single molecule imaging of protein aggregation in Dementia: Methods, insights and prospects.
JSH Danial, D Klenerman
Neurobiol Dis
(2021)
153
(doi: 10.1016/j.nbd.2021.105327)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans
T Sinnige, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, RI Morimoto
Proceedings of the National Academy of Sciences
(2021)
118
(doi: 10.1073/pnas.2021888118)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, K Kaygisiz, F Kirchhoff, TPJ Knowles, FS Ruggeri, CV Synatschke, J Münch, T Weil
Advanced Functional Materials
(2021)
31
(doi: 10.1002/adfm.202009382)
Single-molecule light-sheet microscopy with local nanopipette de-livery.
B Li, A Ponjavic, W-H Chen, L Hopkins, C Hughes, Y Ye, C Bryant, D Klenerman
Analytical Chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c05296)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21181-9)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250.v1)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
One-Step Generation of Multisomes from Lipid-Stabilized Double Emulsions.
MA Czekalska, AMJ Jacobs, Z Toprakcioglu, L Kong, KN Baumann, H Gang, G Zubaite, R Ye, B Mu, A Levin, WTS Huck, TPJ Knowles
ACS Applied Materials and Interfaces
(2021)
13
(doi: 10.1021/acsami.0c16019)
Yusuf Hamied Department of Chemistry
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