Centre for Experimental Biophysical Chemistry

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  • Currently displaying 521 - 540 of 1210 publications
Author(s)
Publication title
Journal Name
Publication year
ThX – a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
Chemical Science
(2020)
11
(doi: 10.1039/c9sc04730a)
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation (Cell Death & Differentiation, (2020), 10.1038/s41418-020-0542-z)
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell Death & Differentiation
(2020)
27
(doi: 10.1038/s41418-020-0552-x)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.04.076299)
A Microfluidic Co-Flow Route for Human Serum Albumin-Drug-Nanoparticle Assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
Chemistry A European Journal
(2020)
26
(doi: 10.1002/chem.202001146)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell Death and Differentiation
(2020)
27
(doi: 10.1038/s41418-020-0542-z)
Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase.
N Esteras, F Kundel, GF Amodeo, EV Pavlov, D Klenerman, AY Abramov
The FEBS journal
(2020)
288
(doi: 10.1111/febs.15340)
Surface electrostatics govern the emulsion stability of biomolecular condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
(doi: 10.1101/2020.04.20.047910)
A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein.
Y Zhao, O Tietz, W-L Kuan, AK Haji-Dheere, S Thompson, B Vallin, E Ronchi, G Tóth, D Klenerman, FI Aigbirhio
Chem Sci
(2020)
11
(doi: 10.1039/c9sc05620c)
Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide (vol 12, pg 445, 2020)
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nature chemistry
(2020)
12
(doi: 10.1038/s41557-020-0468-6)
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nature Chemistry
(2020)
12
(doi: 10.1038/s41557-020-0452-1)
Mechanism of droplet-formation in a supersonic microfluidic spray device
T Kartanas, Z Toprakcioglu, TA Hakala, A Levin, TW Herling, R Daly, J Charmet, TPJ Knowles
Applied Physics Letters
(2020)
116
(doi: 10.1063/1.5145109)
Microfluidic approaches for the analysis of protein–protein interactions in solution
WE Arter, A Levin, G Krainer, TPJ Knowles
Biophysical reviews
(2020)
12
(doi: 10.1007/s12551-020-00679-4)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, L Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, T Drury, A Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, S Lee, T Stevens, D Klenerman, B Hendrich, D Holcman, E Laue
BioRxiv
(2020)
(doi: 10.1101/2020.04.03.003178)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
ACS Chemical Neuroscience
(2020)
11
(doi: 10.1021/acschemneuro.0c00101)
Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain
TM D'Alvise, S Harvey, L Hueske, J Szelwicka, L Veith, TPJ Knowles, D Kubiczek, C Flaig, F Port, K Gottschalk, F Rosenau, B Graczykowski, G Fytas, FS Ruggeri, K Wunderlich, T Weil
Advanced Functional Materials
(2020)
30
(doi: 10.1002/adfm.202000378)
Rapid Fractionation and Characterisation of Alpha-Synuclein Oligomers in Solution
WE Arter, CK Xu, M Castellana-Cruz, TW Herling, G Krainer, KL Saar, JR Kumita, CM Dobson, TPJ Knowles
(2020)
(doi: 10.1101/2020.03.10.985804)
The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils
FS Ruggeri, P Flagmeier, JR Kumita, G Meisl, DY Chirgadze, MN Bongiovanni, TPJ Knowles, CM Dobson
ACS nano
(2020)
14
(doi: 10.1021/acsnano.9b09676)
Effects of sedimentation, microgravity, hydrodynamic mixing and air-water interface on α-synuclein amyloid formation.
J Zhou, FS Ruggeri, MR Zimmermann, G Meisl, G Longo, SK Sekatskii, TPJ Knowles, G Dietler
Chemical science
(2020)
11
(doi: 10.1039/d0sc00281j)
Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GGL Bernandes, TPJ Knowles
Soft Matter
(2020)
16
(doi: 10.1039/c9sm02274k)
Autoantibodies against the prion protein in individuals with PRNP mutations.
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi, THAUTAN-MC Study Group
Neurology
(2020)
95
(doi: 10.1212/WNL.0000000000009183)
Yusuf Hamied Department of Chemistry
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