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Currently displaying 521 - 540 of 1233 publications

Single-molecule visualization of DNA G-quadruplex formation in live cells.

M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, X Zhang, J Shen, L-M Needham, SF Lee, D Klenerman, S Balasubramanian

Nature Chemistry

(2020)

832

(doi: 10.1038/s41557-020-0506-4)

Real-Time Highly-Sensitive Protein Quantification Through On-Chip Chemiluminescence

HK Chiu, T Kartanas, S R. A. Devenish, K Saar, C Mouritsen Luxhøj, T Knowles

(2020)

(doi: 10.26434/chemrxiv.12646376.v1)

Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek, TPJ Knowles, HA Lashuel, E Gazit, IW Hamley, TP Davis, M Fändrich, DE Otzen, MR Chapman, CM Dobson, DS Eisenberg, R Mezzenga

Chem Soc Rev

(2020)

5473

(doi: 10.1039/c9cs00199a)

Continuous Flow Reactors from Microfluidic Compartmentalization of Enzymes within Inorganic Microparticles

TA Hakala, F Bialas, Z Toprakcioglu, B Bräuer, KN Baumann, A Levin, GJL Bernardes, CFW Becker, TPJ Knowles

ACS Applied Materials & Interfaces

(2020)

32951

(doi: 10.1021/acsami.0c09226)

Multidimensional protein characterisation using microfluidic post-column analysis

T Scheidt, T Kartanas, Q Peter, MM Schneider, KL Saar, T Müller, PK Challa, A Levin, S Devenish, TPJ Knowles

Lab Chip

(2020)

2663

(doi: 10.1039/d0lc00219d)

Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Aβ42 Oligomers

FS Ruggeri, J Habchi, S Chia, M Vendruscolo, TPJ Knowles

(2020)

(doi: 10.1101/2020.06.24.168997)

Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses

J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche

Chem Sci

(2020)

7031

(doi: 10.1039/c9sc05905a)

Rational design of a conformation-specific antibody for the quantification of Aβ oligomers

FA Aprile, P Sormanni, M Podpolny, S Chhangur, L-M Needham, FS Ruggeri, M Perni, R Limbocker, GT Heller, T Sneideris, T Scheidt, B Mannini, J Habchi, SF Lee, PC Salinas, TPJ Knowles, CM Dobson, M Vendruscolo

Proceedings of the National Academy of Sciences

(2020)

117

13509

(doi: 10.1073/pnas.1919464117)

Microfluidic Templating of Spatially Inhomogeneous Protein Microgels

Y Xu, RPB Jacquat, Y Shen, D Vigolo, D Morse, S Zhang, TPJ Knowles

Small (Weinheim an der Bergstrasse, Germany)

(2020)

e2000432

(doi: 10.1002/smll.202000432)

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy.

FS Ruggeri, B Mannini, R Schmid, M Vendruscolo, TPJ Knowles

Nature communications

(2020)

2945

(doi: 10.1038/s41467-020-16728-1)

Identification of on- and off-pathway oligomers in amyloid fibril formation.

AJ Dear, G Meisl, A Šarić, TCT Michaels, M Kjaergaard, S Linse, TPJ Knowles

Chem Sci

(2020)

6236

(doi: 10.1039/c9sc06501f)

High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform

WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, P St George-Hyslop, S Alberti, TPJ Knowles

(2020)

2020.06.04.132308

(doi: 10.1101/2020.06.04.132308)

Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large metropolitan region

M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, D Menges, T Ballouz, D Ebner, MM Schneider, IC Morales, B Doğançay, J Guo, A Wiedmer, J Domange, M Imeri, R Moos, C Zografou, L Batkitar, L Madrigal, D Schneider, C Trevisan, A Gonzalez-Guerra, A Carrella, IL Dubach, CK Xu, G Meisl, V Kosmoliaptsis, T Malinauskas, N Burgess-Brown, R Owens, S Hatch, J Mongkolsapaya, GR Screaton, K Schubert, JD Huck, F Liu, F Pojer, K Lau, D Hacker, E Probst-Müller, C Cervia, J Nilsson, O Boyman, L Saleh, K Spanaus, A von Eckardstein, DJ Schaer, N Ban, C-J Tsai, J Marino, GFX Schertler, N Ebert, V Thiel, J Gottschalk, BM Frey, R Reimann, S Hornemann, AM Ring, TPJ Knowles, MA Puhan, CL Althaus, I Xenarios, DI Stuart, A Aguzzi

(2020)

2020.05.31.20118554

(doi: 10.1101/2020.05.31.20118554)

Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses

J Pansieri, IA Iashchishyn, H Fakhouri, L Ostojić, M Malisauskas, G Musteikyte, V Smirnovas, MM Schneider, T Scheidt, CK Xu, G Meisl, TPJ Knowles, E Gazit, R Antoine, LA Morozova-Roche

(2020)

2020.05.26.116400

(doi: 10.1101/2020.05.26.116400)

Direct digital sensing of protein biomarkers in solution

G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles

BIOPHYSICAL JOURNAL

(2020)

120

2020.05.24.113498

(doi: 10.1101/2020.05.24.113498)