Centre for Experimental Biophysical Chemistry

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  • Currently displaying 541 - 560 of 1158 publications
Author(s)
Publication title
Journal Name
Publication year
A method of predicting the in vitro fibril formation propensity of Aβ40 mutants based on their inclusion body levels in E. coli
K Sanagavarapu, E Nüske, I Nasir, G Meisl, JN Immink, P Sormanni, M Vendruscolo, TPJ Knowles, A Malmendal, C Cabaleiro-Lago, S Linse
Scientific Reports
(2019)
9
(doi: 10.1038/s41598-019-39216-z)
Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42
T Weiffert, G Meisl, P Flagmeier, S De, CJR Dunning, B Frohm, H Zetterberg, K Blennow, E Portelius, D Klenerman, CM Dobson, TPJ Knowles, S Linse
ACS Chem Neurosci
(2019)
10
(doi: 10.1021/acschemneuro.8b00676)
Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme.
R Cliffe, JC Sang, F Kundel, D Finley, D Klenerman, Y Ye
Cell Reports
(2019)
26
(doi: 10.1016/j.celrep.2019.01.096)
Simple and ultrafast resonance frequency and dissipation shift measurements using a fixed frequency drive
A Guha, N Sandström, VP Ostanin, W van der Wijngaart, D Klenerman, SK Ghosh
Sensors and Actuators B Chemical
(2019)
281
(doi: 10.1016/j.snb.2018.11.052)
Atomic force microscopy for single molecule characterisation of protein aggregation
FS Ruggeri, T Šneideris, M Vendruscolo, TPJ Knowles
Arch Biochem Biophys
(2019)
664
(doi: 10.1016/j.abb.2019.02.001)
Targeting the Formation of Amyloid Oligomers using Rationally Designed Antibodies
FA Aprile, P Sormanni, M Perni, P Arosio, S Linse, TP Knowles, CM Dobson, M Vendruscolo
Biophysical Journal
(2019)
116
(doi: 10.1016/j.bpj.2018.11.196)
Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis
CD Hughes, ML Choi, M Ryten, L Hopkins, A Drews, JA Botía, M Iljina, M Rodrigues, SA Gagliano, S Gandhi, C Bryant, D Klenerman
Acta Neuropathol
(2019)
137
(doi: 10.1007/s00401-018-1907-y)
Spectrally-Resolved Photodynamics of Individual Emitters in Large-Area Monolayers of Hexagonal-Boron Nitride
HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, L-M Needham, TD Roberts, R Wai, NS Ginsberg, D Klenerman, S Hofmann, SF Lee
(2019)
(doi: 10.48550/arxiv.1901.02793)
Physical Determinants of Amyloid Assembly in Biofilm Formation.
M Andreasen, G Meisl, JD Taylor, TCT Michaels, A Levin, DE Otzen, MR Chapman, CM Dobson, SJ Matthews, TPJ Knowles
mBio
(2019)
10
(doi: 10.1128/mBio.02279-18)
Nanostructured protein capsules
T Knowles
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
258
Imaging rRNA Methylation in Bacteria by MR-FISH
KA Ganzinger, MR Challand, J Spencer, D Klenerman, RT Ranasinghe
Methods Mol Biol
(2019)
2038
(doi: 10.1007/978-1-4939-9674-2_7)
Imaging individual protein aggregates to follow aggregation and determine the role of aggregates in neurodegenerative disease
S De, D Klenerman
Biochimica et biophysica acta. Proteins and proteomics
(2019)
1867
(doi: 10.1016/j.bbapap.2018.12.010)
The presence of autoantibodies against the prion protein is independent of PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, U Camenisch, T Knowles, S Hornemann, A Aguzzi
PRION
(2019)
13
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
(2019)
(doi: 10.2139/ssrn.3312723)
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Analysis of αb-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/C9AN00382G)
Oligomer Diversity during the Aggregation of the Repeat Region of Tau.
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Stabilization and characterization of cytotoxic Aβ40 oligomers isolated from an aggregation reaction in the presence of Zinc ions
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism.
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab Chip
(2018)
19
(doi: 10.1039/c8lc00757h)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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