Centre for Experimental Biophysical Chemistry

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  • Currently displaying 541 - 560 of 1210 publications
Author(s)
Publication title
Journal Name
Publication year
Thermodynamic and kinetic design principles for protein aggregation inhibitors
TCT Michaels, A Šarić, G Meisl, GT Heller, S Curk, P Arosio, S Linse, CM Dobson, M Vendruscolo, TPJ Knowles
(2020)
(doi: 10.1101/2020.02.22.960716)
The molecular processes underpinning prion-like spreading and seed amplification in protein aggregation
G Meisl, TP Knowles, D Klenerman
Curr Opin Neurobiol
(2020)
61
(doi: 10.1016/j.conb.2020.01.010)
Beta amyloid aggregates induce sensitised TLR4 signalling causing long-term potentiation deficit and neuronal cell death in rats
C Hughes, ML Choi, J-H Yi, S-C Kim, A Drews, PS George-Hyslop, C Bryant, S Gandhi, K Cho, D Klenerman
Communications Biology
(2020)
3
(doi: 10.1038/s42003-020-0792-9)
Lipid-Stabilized Double Emulsions Generated in Planar Microfluidic Devices.
L Kong, A Levin, Z Toprakcioglu, Y Xu, H Gang, R Ye, B-Z Mu, TPJ Knowles
Langmuir
(2020)
36
(doi: 10.1021/acs.langmuir.9b03622)
Analysis of α-synuclein species enriched from cerebral cortex of humans with sporadic dementia with Lewy bodies
JB Sanderson, S De, H Jiang, M Rovere, M Jin, L Zaccagnini, A Hays Watson, L De Boni, VN Lagomarsino, TL Young-Pearse, X Liu, TC Pochapsky, BT Hyman, DW Dickson, D Klenerman, DJ Selkoe, T Bartels
Brain Communications
(2020)
2
(doi: 10.1093/braincomms/fcaa010)
Biocompatible Hybrid Organic/Inorganic Microhydrogels Promote Bacterial Adherence and Eradication in Vitro and in Vivo.
L Schnaider, Z Toprakcioglu, A Ezra, X Liu, D Bychenko, A Levin, E Gazit, TPJ Knowles
Nano Lett
(2020)
20
(doi: 10.1021/acs.nanolett.9b04290)
Attoliter protein nanogels from droplet nanofluidics for intracellular delivery.
Z Toprakcioglu, PK Challa, DB Morse, T Knowles
Science advances
(2020)
6
(doi: 10.1126/sciadv.aay7952)
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid‑β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
Quantifying the Thermodynamic Stability of Amyloid Fibrils
KL Callaghan, Q Peter, JR Kumita, TP Knowles, CM Dobson
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2725)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.1878)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2134)
Microfluidic Diffusional Sizing for Studying Protein-Protein Interactions
MM Schneider, T Scheidt, CM Dobson, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2818)
The catalytic nature of protein aggregation
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
The Journal of Chemical Physics
(2020)
152
(doi: 10.1063/1.5133635)
The Costs of Close Contacts: Visualizing the Energy Landscape of Cell Contacts at the Nanoscale.
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, E Jenkins, J Humphrey, A Winkel, K Franze, SF Lee, SJ Davis, D Klenerman
Biophys J
(2020)
118
(doi: 10.1016/j.bpj.2020.01.019)
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Y Shen, FS Ruggeri, D Vigolo, A Kamada, S Qamar, A Levin, C Iserman, S Alberti, P St George-Hyslop, TPJ Knowles
(2020)
(doi: 10.1101/2020.01.21.912857)
MyD88 death domain oligomerisation determines Myddosome architecture: Implications for TLR signalling
MC Moncrieffe, D Bollschweiler, B Li, PA Penczek, L Hopkins, CE Bryant, D Klenerman, NJ Gay
Structure (London, England : 1993)
(2020)
28
(doi: 10.1016/j.str.2020.01.003)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly.
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Chris Dobson (1949–2019)
TPJ Knowles, M Vendruscolo
Nature Chemical Biology
(2020)
16
(doi: 10.1038/s41589-019-0456-6)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, L-M Needham, A Ponjavic, M Da Cunha Santos, J McColl, C Leterrier, SJ Davis, R Henriques, SF Lee
(2020)
(doi: 10.1101/2020.01.20.912733)
A General in Vitro Assay for Studying Enzymatic Activities of the Ubiquitin System
Y Zuo, BK Chong, K Jiang, D Finley, D Klenerman, Y Ye
Biochemistry
(2020)
59
(doi: 10.1021/acs.biochem.9b00602)
Yusuf Hamied Department of Chemistry
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