Centre for Experimental Biophysical Chemistry

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  • Currently displaying 601 - 620 of 1233 publications
Author(s)
Publication title
Journal Name
Publication year
Autoantibodies against the prion protein in individuals with PRNP mutations
K Frontzek, M Carta, M Losa, M Epskamp, G Meisl, A Anane, J-P Brandel, U Camenisch, J Castilla, S Haïk, T Knowles, E Lindner, A Lutterotti, EV Minikel, I Roiter, JG Safar, R Sanchez-Valle, D Žáková, S Hornemann, A Aguzzi
medRxiv
(2019)
(doi: 10.1101/19007773)
A New Platform for Drug Discovery
TP Knowles
Future Drug Discovery
(2019)
1
(doi: 10.4155/fdd-2019-0030)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, PS George-Hyslop, J Lippincott-Schwartz, ME Ward
Cell
(2019)
179
(doi: 10.1016/j.cell.2019.08.050)
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy
FS Ruggeri, T Šneideris, S Chia, M Vendruscolo, TPJ Knowles
Journal of Visualized Experiments
(2019)
(doi: 10.3791/60108-v)
Characterizing individual protein aggregates by infrared nanospectroscopy and atomic force microscopy
FS Ruggeri, T Šneideris, S Chia, M Vendruscolo, TPJ Knowles
JoVE
(2019)
2019
(doi: 10.3791/60108)
N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme.
Y Ye, D Klenerman, D Finley
J Mol Biol
(2019)
432
(doi: 10.1016/j.jmb.2019.08.021)
Scalable integration of nano-, and microfluidics with hybrid 2-photon lithography
O Vanderpoorten, Q Peter, PK Challa, UF Keyser, J Baumberg, CF Kaminski, TPJ Knowles
Microsystems & nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0080-3)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification.
PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, Q Peter, G Jiménez-Osés, TPJ Knowles, CM Dobson, F Corzana, M Vendruscolo, GJL Bernardes
ACS central science
(2019)
5
(doi: 10.1021/acscentsci.9b00467)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
GT Heller, FA Aprile, TCT Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, IC Felli, R Pierattelli, TPJ Knowles, CM Dobson, M Vendruscolo
(2019)
(doi: 10.1101/729392)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression.
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta Neuropathologica Communications
(2019)
7
(doi: 10.1186/s40478-019-0777-4)
ThX – A next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, D T., CK Xu, B Keenlyside, R Cliffe, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
BIOPHYSICAL JOURNAL
(2019)
121
(doi: 10.1101/713594)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017.v1)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017)
The costs of close contacts: Visualizing the energy landscape of cell contacts at the nanoscale
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, SF Lee, SJ Davis, D Klenerman
(2019)
(doi: 10.1101/697672)
Rapid two-dimensional characterisation of proteins in solution
KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles
Microsystems & Nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0072-3)
Universality of filamentous aggregation phenomena.
TCT Michaels, AJ Dear, TPJ Knowles
Phys Rev E
(2019)
99
(doi: 10.1103/PhysRevE.99.062415)
A cell topography-based mechanism for ligand discrimination by the T cell receptor
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
Proc Natl Acad Sci U S A
(2019)
116
(doi: 10.1073/pnas.1817255116)
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis.
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
The Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
Programmable On-Chip Artificial Cell Producing Post-Translationally Modified Ubiquitinated Protein
S Zilberzwige-Tal, A Levin, Z Toprakcioglu, TPJ Knowles, E Gazit, J Elbaz
Small
(2019)
15
(doi: 10.1002/smll.201901780)
Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization
K Mueller
Cell Rep
(2019)
27
(doi: 10.1016/j.celrep.2019.05.038)
Yusuf Hamied Department of Chemistry
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