Centre for Experimental Biophysical Chemistry

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  • Currently displaying 641 - 660 of 1216 publications
Author(s)
Publication title
Journal Name
Publication year
Quantifying Co-Oligomer Formation by α‑Synuclein
M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, TCT Michaels, D Frenkel, CM Dobson, TPJ Knowles, D Klenerman
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b03575)
Filamentous aggregates are fragmented by the proteasome holoenzyme
R Cliffe, JC Sang, F Kundel, D Finley, D Klenerman, Y Ye
Cell Reports
(2018)
(doi: 10.1101/467068)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
Biomed Opt Express
(2018)
9
(doi: 10.1364/boe.9.005863)
Characterisation of particle-surface interactions via anharmonic acoustic transduction
C da Silva Granja, N Sandström, I Efimov, VP Ostanin, W van der Wijngaart, D Klenerman, SK Ghosh
Sensors and Actuators B: Chemical
(2018)
272
(doi: 10.1016/j.snb.2018.05.016)
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform.
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
Journal of visualized experiments : JoVE
(2018)
2018
(doi: 10.3791/58643)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules.
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
J Phys Chem B
(2018)
122
(doi: 10.1021/acs.jpcb.8b07805)
Correction to: Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis (Acta Neuropathologica, (2019), 137, 1, (103-120), 10.1007/s00401-018-1907-y)
CD Hughes, ML Choi, M Ryten, L Hopkins, A Drews, JA Botía, M Iljina, M Rodrigues, SA Gagliano, S Gandhi, C Bryant, D Klenerman
Acta neuropathologica
(2018)
137
(doi: 10.1007/s00401-018-1919-7)
Direct Observation of Murine Prion Protein Replication in Vitro.
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
Journal of the American Chemical Society
(2018)
140
(doi: 10.1021/jacs.8b08311)
¬Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800209)
SAR by kinetics for drug discovery in protein misfolding diseases.
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2018)
115
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-06345-4)
Cover Feature: Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells (ChemBioChem 19/2018)
DR Whiten, Y Zuo, L Calo, M Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800547)
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
Acta Biomater
(2018)
78
(doi: 10.1016/j.actbio.2018.08.010)
Extrinsic Amyloid-Binding Dyes for the Detection of Individual Protein Aggregates in Solution
D Klenerman
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
International Journal of Molecular Sciences
(2018)
19
(doi: 10.3390/ijms19092582)
DNA-Coated Functional Oil Droplets.
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces.
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
ACS Applied Materials & Interfaces
(2018)
10
(doi: 10.1021/acsami.8b09511)
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02051)
Massively parallel C elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
J Neurosci Methods
(2018)
306
(doi: 10.1016/j.jneumeth.2018.02.005)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00353)
Yusuf Hamied Department of Chemistry
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