Centre for Experimental Biophysical Chemistry

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  • Currently displaying 701 - 720 of 1263 publications
Author(s)
Publication title
Journal Name
Publication year
Cover Feature: Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells (ChemBioChem 19/2018)
DR Whiten, Y Zuo, L Calo, M Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800547)
Solution Fibre Spinning Technique for the Fabrication of Tuneable Decellularised Matrix-Laden Fibres and Fibrous Micromembranes
Z Li, J Tuffin, IM Lei, FS Ruggeri, NS Lewis, EL Gill, T Savin, L Huleihel, SF Badylak, T Knowles, SC Satchell, GI Welsh, MA Saleem, YYS Huang
Acta Biomater
(2018)
78
(doi: 10.1016/j.actbio.2018.08.010)
Extrinsic Amyloid-Binding Dyes for Detection of Individual Protein Aggregates in Solution
D Klenerman
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02226)
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy
FS Ruggeri, C Marcott, S Dinarelli, G Longo, M Girasole, G Dietler, TPJ Knowles
International journal of molecular sciences
(2018)
19
(doi: 10.3390/ijms19092582)
DNA-Coated Functional Oil Droplets
A Caciagli, M Zupkauskas, A Levin, TPJ Knowles, C Mugemana, N Bruns, T O'Neill, WJ Frith, E Eiser
Langmuir
(2018)
34
(doi: 10.1021/acs.langmuir.8b01828)
Self-Assembly-Mediated Release of Peptide Nanoparticles through Jets Across Microdroplet Interfaces.
A Levin, TCT Michaels, TO Mason, T Müller, L Adler-Abramovich, L Mahadevan, ME Cates, E Gazit, TPJ Knowles
ACS Applied Materials & Interfaces
(2018)
10
(doi: 10.1021/acsami.8b09511)
Combining Affinity Selection and Specific Ion Mobility for Microchip Protein Sensing
WE Arter, J Charmet, J Kong, KL Saar, TW Herling, T Müller, UF Keyser, TPJ Knowles
Analytical Chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b02051)
Massively parallel C elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, MC Hardenberg, P Sormanni, T Müller, KL Saar, LWY Roode, J Habchi, G Vecchi, N Fernando, S Casford, EAA Nollen, M Vendruscolo, CM Dobson, TPJ Knowles
Journal of Neuroscience Methods
(2018)
306
(doi: 10.1016/j.jneumeth.2018.02.005)
Conserved S/T Residues of the Human Chaperone DNAJB6 Are Required for Effective Inhibition of Aβ42 Amyloid Fibril Formation
C Månsson, RTP van Cruchten, U Weininger, X Yang, R Cukalevski, P Arosio, CM Dobson, T Knowles, M Akke, S Linse, C Emanuelsson
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00353)
Fabrication of Scaffold-Based 3D Magnetic Nanowires for Domain Wall Applications.
D Sanz-Hernández, RF Hamans, J Osterrieth, J-W Liao, L Skoric, JD Fowlkes, PD Rack, A Lippert, SF Lee, R Lavrijsen, A Fernández-Pacheco
Nanomaterials (Basel)
(2018)
8
(doi: 10.3390/nano8070483)
O3‐01‐05: IN VITRO MEASUREMENTS OF TAU AGGREGATE ELONGATION AND FRAGMENTATION RATES ALLOW THE MODELLING OF PRION‐LIKE SPREADING IN HUMANS
D Klenerman, F Kundel, B Falcon, T Knowles, M Goedert, L Hong, W McEwan, G Meisl
Alzheimer's & Dementia
(2018)
14
(doi: 10.1016/j.jalz.2018.06.2774)
O2‐02‐02: TARGETING AMYLOID FORMATION USING RATIONALLY DESIGNED ANTIBODIES
FA Aprile, P Sormanni, M Perni, P Arosio, R Limbocker, S Chhangur, B Mannini, S Linse, T Knowles, CM Dobson, M Vendruscolo
Alzheimer's & Dementia
(2018)
14
(doi: 10.1016/j.jalz.2018.06.2646)
Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine
M Perni, P Flagmeier, R Limbocker, R Cascella, FA Aprile, C Galvagnion, GT Heller, G Meisl, SW Chen, JR Kumita, PK Challa, JB Kirkegaard, SIA Cohen, B Mannini, D Barbut, EAA Nollen, C Cecchi, N Cremades, TPJ Knowles, F Chiti, M Zasloff, M Vendruscolo, CM Dobson
ACS chemical biology
(2018)
13
(doi: 10.1021/acschembio.8b00466)
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
S Basu, L-M Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, W Boucher, YL Tan, LE Bates, O Tkachenko, J Cramard, BC Lagerholm, C Eggeling, B Hendrich, D Klenerman, SF Lee, ED Laue
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-04486-0)
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils.
FS Ruggeri, F Benedetti, TPJ Knowles, HA Lashuel, S Sekatskii, G Dietler
Proceedings of the National Academy of Sciences
(2018)
115
(doi: 10.1073/pnas.1721220115)
Enhancing the Resolution of Micro Free Flow Electrophoresis through Spatially Controlled Sample Injection.
KL Saar, T Müller, J Charmet, PK Challa, TPJ Knowles
Analytical chemistry
(2018)
90
(doi: 10.1021/acs.analchem.8b01205)
Determination of Polypeptide Conformation with Nanoscale Resolution in Water.
G Ramer, FS Ruggeri, A Levin, TPJ Knowles, A Centrone
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b01425)
Single molecule characterisation of the interactions between extracellular chaperones and toxic α-synuclein oligomers
DR Whiten, D Cox, MH Horrocks, CG Taylor, S De, P Flagmeier, L Tosatto, JR Kumita, H Ecroyd, CM Dobson, D Klenerman, MR Wilson
Cell reports
(2018)
23
(doi: 10.1016/j.celrep.2018.05.074)
Origin of metastable oligomers and their effects on amyloid fibril self-assembly.
F Hasecke, T Miti, C Perez, J Barton, D Schölzel, L Gremer, CSR Grüning, G Matthews, G Meisl, TPJ Knowles, D Willbold, P Neudecker, H Heise, G Ullah, W Hoyer, M Muschol
Chem Sci
(2018)
9
(doi: 10.1039/c8sc01479e)
On the role of sidechain size and charge in the aggregation of Aβ42 with familial mutations
X Yang, G Meisl, B Frohm, E Thulin, TPJ Knowles, S Linse
Proceedings of the National Academy of Sciences of the United States of America
(2018)
115
(doi: 10.1073/pnas.1803539115)
Yusuf Hamied Department of Chemistry
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