Centre for Experimental Biophysical Chemistry

Publications

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  • Currently displaying 781 - 800 of 1233 publications
Author(s)
Publication title
Journal Name
Publication year
Direct Modulation of the Mitochondrial Permeability Transition Pore by Oligomeric Alpha-Synuclein Causes Toxicity in PD
M Ludtmann, P Angelova, M-L Choi, M Horrocks, A Baev, D Little, M Devine, P Gissen, E Pavlov, D Klenerman, A Abramov, S Gandhi
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2351)
Kinetics of spontaneous filament nucleation via oligomers: insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
(2017)
(doi: 10.48550/arxiv.1610.02320)
Size dependent structure and effects of amyloid beta42
D Wirthensohn, F Kundel, S De, C Hughes, MH Horrocks, P Flagmeier, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Measuring the prion-like character of tau by TIRF microscopy
F Kundel, B Falcon, L Hong, N Esteras, AJ Dear, AY Abramov, TPJ Knowles, M Goedert, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Q Rev Biophys
(2017)
50
(doi: 10.1017/s0033583516000172)
Mechanisms of Amyloid-β 42 oligomer formation from kinetic analysis
TC Michaels, A Saric, HW Lazell, P Arosio, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
A microfluidic platform for quantitative protein studies
TW Herling, P Arosio, T Mueller, DJ O'Connell, MC Bauer, J Persson, U Weininger, S Linse, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning.
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Kinetics of protein aggregation
T Knowles
FEBS JOURNAL
(2017)
284
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single amyloid aggregates chemical and structural analysis by infrared nanospectroscopy
FS Ruggeri, J Habchi, C Sean, M Vendruscolo, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Imaging the early events of T-cell triggering
D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products.
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab on a Chip
(2017)
18
(doi: 10.1039/c7lc00797c)
Non-perturbative single-molecule imaging of tau aggregates by genetic code expansion
F Kundel, MH Horrocks, Y Ye, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer's disease.
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, P Arosio, JR Kumita, PK Challa, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences
(2016)
114
(doi: 10.1073/pnas.1615613114)
Monitoring Ca
O Tyurikova, K Zheng, A Rings, A Drews, D Klenerman, DA Rusakov
Brain Res Bull
(2016)
136
(doi: 10.1016/j.brainresbull.2016.12.007)
Yusuf Hamied Department of Chemistry
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