Centre for Experimental Biophysical Chemistry

Publications

Tips on using this search form

  • All search terms are case-insensitive
  • If you specify more than one search option (e.g. you search for both "Authors" and "Paper title") then the publications returned will be those that match all of your search terms
  • To reset the search form, click here
  • Currently displaying 781 - 800 of 1158 publications
Author(s)
Publication title
Journal Name
Publication year
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α‑Synuclein Oligomers
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
Anal Chem
(2015)
87
(doi: 10.1021/acs.analchem.5b01811)
Force generation by the growth of amyloid aggregates.
TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles
Proc Natl Acad Sci U S A
(2015)
112
(doi: 10.1073/pnas.1417326112)
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation.
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
The Journal of Chemical Physics
(2015)
143
(doi: 10.1063/1.4927655)
Molecular Rotors Provide Insights into Microscopic Structural Changes during Protein Aggregation
AJ Thompson, TW Herling, M Kubánková, A Vyšniauskas, TPJ Knowles, MK Kuimova
The Journal of Physical Chemistry B
(2015)
119
(doi: 10.1021/acs.jpcb.5b05099)
Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons.
AK Reeve, MHR Ludtmann, PR Angelova, EM Simcox, MH Horrocks, D Klenerman, S Gandhi, DM Turnbull, AY Abramov
Cell Death and Disease
(2015)
6
(doi: 10.1038/cddis.2015.166)
Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus.
DJ Whitcomb, EL Hogg, P Regan, T Piers, P Narayan, G Whitehead, BL Winters, D-H Kim, E Kim, P St George-Hyslop, D Klenerman, GL Collingridge, J Jo, K Cho
Scientific Reports
(2015)
5
(doi: 10.1038/srep10934)
Enzymatically Active Microgels from Self-Assembling Protein Nanofibrils for Microflow Chemistry
X-M Zhou, U Shimanovich, TW Herling, S Wu, CM Dobson, TPJ Knowles, S Perrett
ACS nano
(2015)
9
(doi: 10.1021/acsnano.5b00061)
Neuronal Cx3cr1 Deficiency Protects against Amyloid β-Induced Neurotoxicity.
J Dworzak, B Renvoisé, J Habchi, EV Yates, C Combadière, TP Knowles, CM Dobson, C Blackstone, O Paulsen, PM Murphy
Plos One
(2015)
10
(doi: 10.1371/journal.pone.0127730)
Aggregation-Prone Amyloid-β⋅Cu(II) Species Formed on the Millisecond Timescale under Mildly Acidic Conditions.
JT Pedersen, CB Borg, TCT Michaels, TPJ Knowles, P Faller, K Teilum, L Hemmingsen
Chembiochem : a European journal of chemical biology
(2015)
16
(doi: 10.1002/cbic.201500080)
The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation
R Cukalevski, X Yang, G Meisl, U Weininger, K Bernfur, B Frohm, TPJ Knowles, S Linse
Chemical Science
(2015)
6
(doi: 10.1039/c4sc02517b)
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers.
SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, E Mandelkow, TPJ Knowles, E Mandelkow, D Klenerman
Nat Commun
(2015)
6
(doi: 10.1038/ncomms8025)
Preventing peptide and protein misbehavior
P Arosio, G Meisl, M Andreasen, TPJ Knowles
Proc Natl Acad Sci U S A
(2015)
112
(doi: 10.1073/pnas.1505170112)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, MM Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, GE De, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112.)
On-demand delivery of single DNA molecules using nanopipets.
AP Ivanov, P Actis, P Jönsson, D Klenerman, Y Korchev, JB Edel
ACS Nano
(2015)
9
(doi: 10.1021/acsnano.5b00911)
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
Journal of Neurochemistry
(2015)
133
(doi: 10.1111/jnc.13024)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstål, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature structural & molecular biology
(2015)
22
(doi: 10.1038/nsmb.2971)
The physical basis of protein misfolding disorders
TPJ Knowles, M Vendruscolo, CM Dobson
Physics Today
(2015)
68
(doi: 10.1063/pt.3.2719)
Lipid peroxidation is essential for α-synuclein-induced cell death.
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
J Neurochem
(2015)
133
(doi: 10.1111/jnc.13024)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers.
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstal, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature Structural and Molecular Biology
(2015)
22
(doi: 10.1038/nsmb.2971)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
Contacts
Directions

Privacy and cookie policy

About the Department

Departmental Services

Contact The Centre for Experimental Biophysical Chemistry

Email: biophysicalchemistry@ch.cam.ac.uk

Study at Cambridge

About the University

Research at Cambridge