Centre for Experimental Biophysical Chemistry

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  • Currently displaying 861 - 880 of 1233 publications
Author(s)
Publication title
Journal Name
Publication year
Hamiltonian Dynamics of Protein Filament Formation
TCT Michaels, SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Phys Rev Lett
(2016)
116
(doi: 10.1103/PhysRevLett.116.038101)
Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide.
G Meisl, X Yang, B Frohm, TPJ Knowles, S Linse
Scientific Reports
(2016)
6
(doi: 10.1038/srep18728)
Molecular mechanisms of protein aggregation from global fitting of kinetic models
G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
Nat Protoc
(2016)
11
(doi: 10.1038/nprot.2016.010)
A novel single molecule imaging approach to detect individual protein oligomers in CSF from patients with Parkinson's disease (PD)
S Gandhi, MH Horrocks, SF Lee, NW Wood, D Klenerman
MOVEMENT DISORDERS
(2016)
31
A single-molecule approach to deciphering the mechanism of T-cell receptor triggering.
KA Ganzinger, R Fernandes, S Lee, M Palayret, P Jonsson, J McColl, SJ Davis, D Klenerman
MOLECULAR BIOLOGY OF THE CELL
(2016)
27
Microfluidic devices fabricated using soft lithography for the study of protein structures using synchrotron radiation circular dichroism
J Charmet, C Bortolini, D Copic, IC Morales, Y Zhang, PK Challa, T Jávorfi, R Hussain, G Siligardi, TPJ Knowles
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2016
(2016)
A kinetic model of the aggregation of α-synuclein provides insights into prion-like spreading
M Iljina, G Garcia, MH Horrocks, L Tosatto, M Choi, S Gandhi, T Knowles, D Klenerman
PRION
(2016)
10
Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions.
P Arosio, T Müller, L Rajah, EV Yates, FA Aprile, Y Zhang, SIA Cohen, DA White, TW Herling, EJ De Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
ACS nano
(2015)
10
(doi: 10.1021/acsnano.5b04713)
Consistent treatment of hydrophobicity in protein lattice models accounts for cold denaturation
E van Dijk, P Varilly, T Knowles, D Frenkel, S Abeln
(2015)
(doi: 10.48550/arxiv.1511.06590)
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants
L Tosatto, MH Horrocks, AJ Dear, TPJ Knowles, M Dalla Serra, N Cremades, CM Dobson, D Klenerman
Scientific reports
(2015)
5
(doi: 10.1038/srep16696)
N-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42.
O Szczepankiewicz, B Linse, G Meisl, E Thulin, B Frohm, C Sala Frigerio, MT Colvin, AC Jacavone, RG Griffin, T Knowles, DM Walsh, S Linse
J Am Chem Soc
(2015)
137
(doi: 10.1021/jacs.5b07849)
CalQuo: automated, simultaneous single-cell and population-level quantification of global intracellular Ca2+ responses
M Fritzsche, RA Fernandes, H Colin-York, AM Santos, SF Lee, BC Lagerholm, SJ Davis, C Eggeling
Scientific Reports
(2015)
5
(doi: 10.1038/srep16487)
Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States
SL Latty, JH Felce, L Weimann, SF Lee, SJ Davis, D Klenerman
Biophysical journal
(2015)
109
(doi: 10.1016/j.bpj.2015.09.004)
The length distribution of frangible biofilaments.
TCT Michaels, P Yde, JCW Willis, MH Jensen, D Otzen, CM Dobson, AK Buell, TPJ Knowles
The Journal of chemical physics
(2015)
143
(doi: 10.1063/1.4933230)
ChemInform Abstract: Biophysical Approaches for the Study of Interactions Between Molecular Chaperones and Protein Aggregates
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
ChemInform
(2015)
46
(doi: 10.1002/chin.201545294)
Particle-based simulations of steady-state mass transport at high Péclet numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
(2015)
(doi: 10.48550/arxiv.1510.05126)
The 2015 super-resolution microscopy roadmap
SW Hell, SJ Sahl, M Bates, X Zhuang, R Heintzmann, MJ Booth, J Bewersdorf, G Shtengel, H Hess, P Tinnefeld, A Honigmann, S Jakobs, I Testa, L Cognet, B Lounis, H Ewers, SJ Davis, C Eggeling, D Klenerman, KI Willig, G Vicidomini, M Castello, A Diaspro, T Cordes
Journal of Physics D
(2015)
48
(doi: 10.1088/0022-3727/48/44/443001)
Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity
EV Yates, T Müller, L Rajah, EJ De Genst, P Arosio, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles
Nature chemistry
(2015)
7
(doi: 10.1038/NCHEM.2344)
Fast Flow Microfluidics and Single-Molecule Fluorescence for the Rapid Characterization of α‑Synuclein Oligomers
MH Horrocks, L Tosatto, AJ Dear, GA Garcia, M Iljina, N Cremades, M Dalla Serra, TPJ Knowles, CM Dobson, D Klenerman
Analytical chemistry
(2015)
87
(doi: 10.1021/acs.analchem.5b01811)
Force generation by the growth of amyloid aggregates
TW Herling, GA Garcia, TCT Michaels, W Grentz, J Dean, U Shimanovich, H Gang, T Müller, B Kav, EM Terentjev, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1417326112)
Yusuf Hamied Department of Chemistry
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