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Currently displaying 861 - 880 of 1256 publications

Amyloid Fibrils as Building Blocks for Natural and Artificial Functional Materials.

TPJ Knowles, R Mezzenga

Advanced materials (Deerfield Beach, Fla.)

(2016)

6546

(doi: 10.1002/adma.201505961)

A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions.

TW Herling, DJ O'Connell, MC Bauer, J Persson, U Weininger, TPJ Knowles, S Linse

Biophysical journal

(2016)

110

1957

(doi: 10.1016/j.bpj.2016.03.038)

Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism.

CLL Pham, A Rey, V Lo, M Soulès, Q Ren, G Meisl, TPJ Knowles, AH Kwan, M Sunde

Scientific reports

(2016)

25288

(doi: 10.1038/srep25288)

PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits.

MJ Broadhead, MH Horrocks, F Zhu, L Muresan, R Benavides-Piccione, J DeFelipe, D Fricker, MV Kopanitsa, RR Duncan, D Klenerman, NH Komiyama, SF Lee, SGN Grant

Sci Rep

(2016)

24626

(doi: 10.1038/srep24626)

Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones.

JD Taylor, WJ Hawthorne, J Lo, A Dear, N Jain, G Meisl, M Andreasen, C Fletcher, M Koch, N Darvill, N Scull, A Escalera-Maurer, L Sefer, R Wenman, S Lambert, J Jean, Y Xu, B Turner, SG Kazarian, MR Chapman, D Bubeck, A de Simone, TPJ Knowles, SJ Matthews

Sci Rep

(2016)

24656

(doi: 10.1038/srep24656)

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

V Kakkar, C Månsson, EP de Mattos, S Bergink, M van der Zwaag, MAWH van Waarde, NJ Kloosterhuis, R Melki, RTP van Cruchten, S Al-Karadaghi, P Arosio, CM Dobson, TPJ Knowles, GP Bates, JM van Deursen, S Linse, B van de Sluis, C Emanuelsson, HH Kampinga

Molecular Cell

(2016)

272

(doi: 10.1016/j.molcel.2016.03.017)

A general reaction network unifies the aggregation behaviour of the A$β$42 peptide and its variants

G Meisl, X Yang, CM Dobson, S Linse, TPJ Knowles

(2016)

(doi: 10.48550/arxiv.1604.00828)

Analysis of the length distribution of amyloid fibrils by centrifugal sedimentation.

P Arosio, T Cedervall, TPJ Knowles, S Linse

Analytical Biochemistry

(2016)

504

(doi: 10.1016/j.ab.2016.03.015)

Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation.

P Arosio, TCT Michaels, S Linse, C Månsson, C Emanuelsson, J Presto, J Johansson, M Vendruscolo, CM Dobson, TPJ Knowles

Nature Communications

(2016)

10948

(doi: 10.1038/ncomms10948)

Initiation of T cell signaling by CD45 segregation at 'close contacts'.

VT Chang, RA Fernandes, KA Ganzinger, SF Lee, C Siebold, J McColl, P Jönsson, M Palayret, K Harlos, CH Coles, EY Jones, Y Lui, E Huang, RJC Gilbert, D Klenerman, AR Aricescu, SJ Davis

Nature immunology

(2016)

574

(doi: 10.1038/ni.3392)