Centre for Experimental Biophysical Chemistry

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  • Currently displaying 861 - 880 of 1276 publications
Author(s)
Publication title
Journal Name
Publication year
Kinetics of fragmentation and dissociation of two-strand protein filaments: Coarse-grained simulations and experiments.
A Zaccone, I Terentjev, TW Herling, TPJ Knowles, A Aleksandrova, EM Terentjev
The Journal of chemical physics
(2016)
145
(doi: 10.1063/1.4962366)
Physical determinants of the self-replication of protein fibrils.
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, TPJ Knowles, D Frenkel
Nature physics
(2016)
12
(doi: 10.1038/NPHYS3828)
A microfluidic platform for trapping, releasing and super-resolution imaging of single cells.
Y Zhou, S Basu, KJ Wohlfahrt, SF Lee, D Klenerman, ED Laue, AA Seshia
Sensors and actuators. B, Chemical
(2016)
232
(doi: 10.1016/j.snb.2016.03.131)
Mutations associated with familial Parkinson’s disease alter the initiation and amplification steps of α-synuclein aggregation
P Flagmeier, G Meisl, M Vendruscolo, TPJ Knowles, CM Dobson, AK Buell, C Galvagnion
Proceedings of the National Academy of Sciences
(2016)
113
(doi: 10.1073/pnas.1604645113)
Protein Aggregate-Ligand Binding Assays Based on Microfluidic Diffusional Separation
Y Zhang, AK Buell, T Müller, E De Genst, J Benesch, CM Dobson, TPJ Knowles
Chembiochem
(2016)
17
(doi: 10.1002/cbic.201600384)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells.
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Sci Rep
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly.
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform
TO Mason, TCT Michaels, A Levin, E Gazit, CM Dobson, AK Buell, TPJ Knowles
Journal of the American Chemical Society
(2016)
138
(doi: 10.1021/jacs.6b04136)
The Nucleosome Remodeling and Deacetylase Complex NuRD is built from preformed catalytically active sub-modules
W Zhang, A Aubert, JM Gomez de Segura, M Karuppasamy, S Basu, A Murthy, A Diamante, TA Drury, J Balmer, J Cramard, AA Watson, D Lando, SF Lee, M Palayret, S Kloet, A Smits, M Deery, M Vermeulen, B Hendrich, D Klenerman, C Schaffitzel, I Berger, ED Laue
Journal of Molecular Biology
(2016)
428
(doi: 10.1016/j.jmb.2016.04.025)
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms.
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep28658)
Quantifying Measurement Fluctuations from Stochastic Surface Processes on Sensors with Heterogeneous Sensitivity
J Charmet, TCT Michaels, R Daly, A Prasad, P Thiruvenkathanathan, RS Langley, TPJ Knowles, AA Seshia
Physical Review Applied
(2016)
5
(doi: 10.1103/physrevapplied.5.064016)
Fluctuations in the Kinetics of Linear Protein Self-Assembly
TCT Michaels, AJ Dear, JB Kirkegaard, KL Saar, DA Weitz, TPJ Knowles
Physical Review Letters
(2016)
116
(doi: 10.1103/PhysRevLett.116.258103)
Studying the Dynamics of Chromatin-Binding Proteins in Mammalian Cells Using Single-Molecule Localisation Microscopy.
S Basu, YL Tan, EJR Taylor, ED Laue, SF Lee
Methods Mol Biol
(2016)
1431
(doi: 10.1007/978-1-4939-3631-1_17)
A novel single molecule imaging approach to detect individual protein oligomers in CSF from patients with Parkinson's disease (PD)
S Gandhi, MH Horrocks, SF Lee, NW Wood, D Klenerman
MOVEMENT DISORDERS
(2016)
31
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Peclet Numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2016)
17
(doi: 10.1515/ijnsns-2015-0056)
Angular Approach Scanning Ion Conductance Microscopy
A Shevchuk, S Tokar, S Gopal, JL Sanchez-Alonso, AI Tarasov, AC Vélez-Ortega, C Chiappini, P Rorsman, MM Stevens, J Gorelik, GI Frolenkov, D Klenerman, YE Korchev
Biophysical Journal
(2016)
110
(doi: 10.1016/j.bpj.2016.04.017)
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions.
P Jönsson, J Southcombe, AM Santos, J Huo, RA Fernandes, J McColl, M Lever, EJ Evans, A Hudson, VT Chang, T Hanke, A Godkin, PD Dunne, MH Horrocks, M Palayret, GR Screaton, J Petersen, J Rossjohn, L Fugger, O Dushek, X Xu, SJ Davis, D Klenerman
Proc Natl Acad Sci U S A
(2016)
113
(doi: 10.1073/pnas.1513918113)
Ca2+ is a key factor in α-synuclein-induced neurotoxicity
PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, D Klenerman, CM Dobson, NW Wood, EV Pavlov, S Gandhi, AY Abramov
Development
(2016)
143
(doi: 10.1242/dev.139345)
Amyloid Fibrils as Building Blocks for Natural and Artificial Functional Materials
TPJ Knowles, R Mezzenga
Advanced materials (Deerfield Beach, Fla.)
(2016)
28
(doi: 10.1002/adma.201505961)
A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions.
TW Herling, DJ O'Connell, MC Bauer, J Persson, U Weininger, TPJ Knowles, S Linse
Biophysical Journal
(2016)
110
(doi: 10.1016/j.bpj.2016.03.038)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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