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Currently displaying 821 - 840 of 1199 publications

Automated Ex Situ Assays of Amyloid Formation on a Microfluidic Platform.

K-L Saar, EV Yates, T Müller, S Saunier, CM Dobson, TPJ Knowles

Biophysical journal

(2016)

110

555

(doi: 10.1016/j.bpj.2015.11.3523)

3D Super-Resolution Imaging of Unperturbed Cells

AR Carr, J McCol;, AM Santos, J-E Lee, A Ponjavic, D Klenerman, S Davis, SF Lee

Biophysical Journal

(2016)

110

485a

(doi: 10.1016/j.bpj.2015.11.2595)

Improved Photo Physical Properties of mEos3 for Single Molecule Tracking

L-M Needham, S Basu, E Taylor, ED Laue, D Klenerman, D Lando, SF Lee

Biophysical Journal

(2016)

110

485A

(doi: 10.1016/j.bpj.2015.11.2596)

Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis.

Y Zhang, J Clausmeyer, B Babakinejad, AL Córdoba, T Ali, A Shevchuk, Y Takahashi, P Novak, C Edwards, M Lab, S Gopal, C Chiappini, U Anand, L Magnani, RC Coombes, J Gorelik, T Matsue, W Schuhmann, D Klenerman, EV Sviderskaya, Y Korchev

ACS nano

(2016)

3214

(doi: 10.1021/acsnano.5b05211)

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

E Deas, N Cremades, PR Angelova, MHR Ludtmann, Z Yao, S Chen, MH Horrocks, B Banushi, D Little, MJ Devine, P Gissen, D Klenerman, CM Dobson, NW Wood, S Gandhi, AY Abramov

Antioxid Redox Signal

(2016)

376

(doi: 10.1089/ars.2015.6343)

Combining Single-Molecule Techniques with Microfluidics for Protein Analysis

C Taylor, T Knowles, D Klenerman

Biophysical Journal

(2016)

110

195A

(doi: 10.1016/j.bpj.2015.11.1086)

Hamiltonian Dynamics of Protein Filament Formation

TCT Michaels, SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles

Phys Rev Lett

(2016)

116

038101

(doi: 10.1103/physrevlett.116.038101)

Quantitative analysis of intrinsic and extrinsic factors in the aggregation mechanism of Alzheimer-associated Aβ-peptide.

G Meisl, X Yang, B Frohm, TPJ Knowles, S Linse

Sci Rep

(2016)

18728

(doi: 10.1038/srep18728)

Molecular mechanisms of protein aggregation from global fitting of kinetic models.

G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles

Nature Protocols

(2016)

252

(doi: 10.1038/nprot.2016.010)

A novel single molecule imaging approach to detect individual protein oligomers in CSF from patients with Parkinson's disease (PD)

S Gandhi, MH Horrocks, SF Lee, NW Wood, D Klenerman

MOVEMENT DISORDERS

(2016)

S281

Microfluidic devices fabricated using soft lithography for the study of protein structures using synchrotron radiation circular dichroism

J Charmet, C Bortolini, D Copic, IC Morales, Y Zhang, PK Challa, T Jávorfi, R Hussain, G Siligardi, TPJ Knowles

20th International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2016

(2016)

1079

A kinetic model of the aggregation of α-synuclein provides insights into prion-like spreading

M Iljina, G Garcia, MH Horrocks, L Tosatto, M Choi, S Gandhi, T Knowles, D Klenerman

PRION

(2016)

S63

A single-molecule approach to deciphering the mechanism of T-cell receptor triggering.

KA Ganzinger, R Fernandes, S Lee, M Palayret, P Jonsson, J McColl, SJ Davis, D Klenerman

MOLECULAR BIOLOGY OF THE CELL

(2016)

Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions.

P Arosio, T Müller, L Rajah, EV Yates, FA Aprile, Y Zhang, SIA Cohen, DA White, TW Herling, EJ De Genst, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles

ACS Nano

(2015)

333

(doi: 10.1021/acsnano.5b04713)