Centre for Experimental Biophysical Chemistry

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  • Currently displaying 561 - 580 of 1256 publications
Author(s)
Publication title
Journal Name
Publication year
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.24.113498)
Digital Sensing and Molecular Computation by an Enzyme-Free DNA Circuit
WE Arter, Y Yusim, Q Peter, CG Taylor, D Klenerman, UF Keyser, TPJ Knowles
ACS Nano
(2020)
14
(doi: 10.1021/acsnano.0c00628)
Single Molecule Light Field Microscopy
RR Sims, SA Rehman, MO Lenz, A Clark, EW Sanders, A Ponjavic, L Muresan, SF Lee, K O’Holleran
(2020)
(doi: 10.1101/2020.05.20.104802)
Ultrastructural evidence for self-replication of alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Törnquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, A Malmendal, M Akke, S Linse
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1918481117)
Assessing motor-related phenotypes of Caenorhabditis elegans with the wide field-of-view nematode tracking platform
M Koopman, Q Peter, RI Seinstra, M Perni, M Vendruscolo, CM Dobson, TPJ Knowles, EAA Nollen
Nature Protocols
(2020)
15
(doi: 10.1038/s41596-020-0321-9)
Kinetic diversity of amyloid oligomers.
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, CM Dobson, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.1922267117)
ThX - a next-generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, R Cliffe, B Keenlyside, D Klenerman, CM Dobson, CA Hunter, KH Müller, K O'Holleran, SE Bohndiek, TN Snaddon, SF Lee
Chemical Science
(2020)
11
(doi: 10.1039/c9sc04730a)
Correction: Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation.
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell Death & Differentiation
(2020)
27
(doi: 10.1038/s41418-020-0552-x)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
120
(doi: 10.1101/2020.05.04.076299)
A Microfluidic Co-Flow Route for Human Serum Albumin-drugnanoparticle assembly
TA Hakala, S Davies, Z Toprakcioglu, B Bernardim, GJL Bernardes, TPJ Knowles
Chemistry – A European Journal
(2020)
26
(doi: 10.1002/chem.202001146)
Alpha synuclein aggregation drives ferroptosis: an interplay of iron, calcium and lipid peroxidation
PR Angelova, ML Choi, AV Berezhnov, MH Horrocks, CD Hughes, S De, M Rodrigues, R Yapom, D Little, KS Dolt, T Kunath, MJ Devine, P Gissen, MS Shchepinov, S Sylantyev, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Cell death and differentiation
(2020)
27
(doi: 10.1038/s41418-020-0542-z)
Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase
N Esteras, F Kundel, GF Amodeo, EV Pavlov, D Klenerman, AY Abramov
The FEBS Journal
(2020)
288
(doi: 10.1111/febs.15340)
Surface electrostatics govern the emulsion stability of biomolecular condensates
TJ Welsh, G Krainer, JR Espinosa, JA Joseph, A Sridhar, M Jahnel, WE Arter, KL Saar, S Alberti, R Collepardo-Guevara, TPJ Knowles
(2020)
(doi: 10.1101/2020.04.20.047910)
A fluorescent molecular imaging probe with selectivity for soluble tau aggregated protein
Y Zhao, O Tietz, W-L Kuan, AK Haji-Dheere, S Thompson, B Vallin, E Ronchi, G Tóth, D Klenerman, FI Aigbirhio
Chemical science
(2020)
11
(doi: 10.1039/c9sc05620c)
Author Correction: Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide (Nature Chemistry, (2020), 12, 5, (445-451), 10.1038/s41557-020-0452-1)
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nature Chemistry
(2020)
12
(doi: 10.1038/s41557-020-0468-6)
Dynamics of oligomer populations formed during the aggregation of Alzheimer's Aβ42 peptide.
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, SIA Cohen, CM Dobson, M Vendruscolo, S Linse, TPJ Knowles
Nat Chem
(2020)
12
(doi: 10.1038/s41557-020-0452-1)
Mechanism of droplet-formation in a supersonic microfluidic spray device
T Kartanas, Z Toprakcioglu, TA Hakala, A Levin, TW Herling, R Daly, J Charmet, TPJ Knowles
Applied Physics Letters
(2020)
116
(doi: 10.1063/1.5145109)
Microfluidic approaches for the analysis of protein–protein interactions in solution
WE Arter, A Levin, G Krainer, TPJ Knowles
Biophysical Reviews
(2020)
12
(doi: 10.1007/s12551-020-00679-4)
Live-cell 3D single-molecule tracking reveals how NuRD modulates enhancer dynamics
S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, D Lando, W Zhang, N Reynolds, L Sober, A Jartseva, R Ragheb, X Ma, J Cramard, R Floyd, G Brown, J Balmer, T Drury, A Carr, L-M Needham, A Aubert, G Communie, K Gor, M Steindel, L Morey, E Blanco, T Bartke, L Di Croce, I Berger, C Schaffitzel, S Lee, T Stevens, D Klenerman, B Hendrich, D Holcman, E Laue
BioRxiv
(2020)
(doi: 10.1101/2020.04.03.003178)
Complexity in Lipid Membrane Composition Induces Resilience to Aβ42 Aggregation
M Sanguanini, KN Baumann, S Preet, S Chia, J Habchi, TPJ Knowles, M Vendruscolo
ACS Chem Neurosci
(2020)
11
(doi: 10.1021/acschemneuro.0c00101)
Yusuf Hamied Department of Chemistry
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