Centre for Experimental Biophysical Chemistry

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  • Currently displaying 481 - 500 of 1158 publications
Author(s)
Publication title
Journal Name
Publication year
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid‑β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, R Cascella, CM Dobson, M Vendruscolo, TPJ Knowles, F Chiti
Biomacromolecules
(2020)
21
(doi: 10.1021/acs.biomac.9b01475)
Quantifying the Thermodynamic Stability of Amyloid Fibrils
KL Callaghan, Q Peter, JR Kumita, TP Knowles, CM Dobson
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2725)
Molecular Forces in the Liquid-Liquid Phase Separation of Biomolecules
TJ Welsh, G Krainer, TP Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2134)
Microfluidic Diffusional Sizing for Studying Protein-Protein Interactions
MM Schneider, T Scheidt, CM Dobson, TPJ Knowles
Biophysical Journal
(2020)
118
(doi: 10.1016/j.bpj.2019.11.2818)
The costs of close contacts: Visualizing the energy landscape of cell contacts at the nanoscale
K Kulenkampff, AH Lippert, J McColl, AM Santos, A Ponjavic, E Jenkins, J Humphrey, A Winkel, K Franze, SF Lee, SJ Davis, D Klenerman
Biophys J
(2020)
118
(doi: 10.1016/j.bpj.2020.01.019)
MyD88 Death-Domain Oligomerization Determines Myddosome Architecture: Implications for Toll-like Receptor Signaling.
MC Moncrieffe, D Bollschweiler, B Li, PA Penczek, L Hopkins, CE Bryant, D Klenerman, NJ Gay
Structure
(2020)
28
(doi: 10.1016/j.str.2020.01.003)
The catalytic nature of protein aggregation
AJ Dear, G Meisl, TCT Michaels, MR Zimmermann, S Linse, TPJ Knowles
The Journal of Chemical Physics
(2020)
152
(doi: 10.1063/1.5133635)
Coating and Stabilization of Liposomes by Clathrin-Inspired DNA Self-Assembly.
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S Hernández-Ainsa
ACS Nano
(2020)
14
(doi: 10.1021/acsnano.9b09453)
Chris Dobson (1949-2019)
TPJ Knowles, M Vendruscolo
Nature Chemical Biology
(2020)
16
(doi: 10.1038/s41589-019-0456-6)
vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy
A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, L-M Needham, A Ponjavic, M Da Cunha Santos, J McColl, C Leterrier, SJ Davis, R Henriques, SF Lee
(2020)
(doi: 10.1101/2020.01.20.912733)
A general in vitro assay for studying enzymatic activities of the ubiquitin system
Y Zuo, BK Chong, K Jiang, D Finley, D Klenerman, Y Ye
Biochemistry
(2020)
59
(doi: 10.1021/acs.biochem.9b00602)
Local micro and nano patterning of microfluidic devices using the solid on liquid deposition process
J Charmet, A Homsy, M Wood, J Covington, L Isa, M Textor, TPJ Knowles, H Keppner
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences Microtas 2017
(2020)
A microfluidic strategy for the detection of membrane protein interactions.
Y Zhang, TW Herling, S Kreida, QAE Peter, T Kartanas, S Törnroth-Horsefield, S Linse, TPJ Knowles
Lab Chip
(2020)
20
(doi: 10.1039/d0lc00205d)
Investigation of Natural and Synthetic Aggregation Inhibitors using Microfluidic Applications
T Scheidt, J Carozza, JL Benesch, P Arosio, S Linse, TPJ Knowles
BIOPHYSICAL JOURNAL
(2020)
118
Homage to Chris Dobson.
J Baum, F Chiti, A De Simone, TPJ Knowles, JR Kumita, SE Radford, CV Robinson, X Salvatella, K Valelli, M Vendruscolo, A Pastore, GG Tartaglia
Frontiers in Molecular Biosciences
(2019)
6
(doi: 10.3389/fmolb.2019.00137)
High-resolution label-free 3D mapping of extracellular pH of single living cells.
Y Zhang, Y Takahashi, SP Hong, F Liu, J Bednarska, PS Goff, P Novak, A Shevchuk, S Gopal, I Barozzi, L Magnani, H Sakai, Y Suguru, T Fujii, A Erofeev, P Gorelkin, A Majouga, DJ Weiss, C Edwards, AP Ivanov, D Klenerman, EV Sviderskaya, JB Edel, Y Korchev
Nature communications
(2019)
10
(doi: 10.1038/s41467-019-13535-1)
α-Synuclein strains target distinct brain regions and cell types
A Lau, RWL So, HHC Lau, JC Sang, A Ruiz-Riquelme, SC Fleck, E Stuart, S Menon, NP Visanji, G Meisl, R Faidi, MM Marano, C Schmitt-Ulms, Z Wang, PE Fraser, A Tandon, BT Hyman, H Wille, M Ingelsson, D Klenerman, JC Watts
Nature neuroscience
(2019)
23
(doi: 10.1038/s41593-019-0541-x)
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, B Mannini, J Habchi, TCT Michaels, PK Challa, M Ahn, ST Casford, N Fernando, CK Xu, ND Kloss, SIA Cohen, JR Kumita, C Cecchi, M Zasloff, S Linse, TPJ Knowles, F Chiti, M Vendruscolo, CM Dobson
Nature communications
(2019)
10
(doi: 10.1038/s41467-018-07699-5)
Label-Free Analysis of Protein Aggregation and Phase Behavior
Z Toprakcioglu, P Challa, C Xu, TPJ Knowles
ACS Nano
(2019)
13
(doi: 10.1021/acsnano.9b05552)
Protein Microgels from Amyloid Fibril Networks
LWY Roode, U Shimanovich, S Wu, S Perrett, TPJ Knowles
Advances in Experimental Medicine and Biology
(2019)
1174
(doi: 10.1007/978-981-13-9791-2_7)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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enquiries@ch.cam.ac.uk
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