Centre for Experimental Biophysical Chemistry

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  • Currently displaying 461 - 480 of 1272 publications
Author(s)
Publication title
Journal Name
Publication year
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
S Fiedler, V Denninger, AS Morgunov, A Ilsley, R Worth, G Meisl, CK Xu, MA Piziorska, F Ricci, AY Malik, SRA Devenish, MM Schneider, V Kosmoliaptsis, A Aguzzi, A Iwasaki, H Fiegler, TPJ Knowles
(2021)
(doi: 10.1101/2021.07.23.453327)
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies.
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
EMBO Mol Med
(2021)
13
(doi: 10.15252/emmm.202114745)
Understanding the role of memory re-activation and cross-reactivity in the defense against SARS-CoV-2
V Denninger, CK Xu, G Meisl, AS Morgunov, S Fiedler, A Ilsley, M Emmenegger, AY Malik, MA Piziorska, MM Schneider, SRA Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, TPJ Knowles
(2021)
(doi: 10.1101/2021.07.23.453352)
Liquid-Liquid Phase-Separated Systems from Reversible Gel-Sol Transition of Protein Microgels
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202008670)
The unhappy chaperone
S Linse, K Thalberg, TPJ Knowles
QRB Discov
(2021)
2
(doi: 10.1017/qrd.2021.5)
Protein Conjugation by Electrophilic Alkynylation Using 5‑(Alkynyl)dibenzothiophenium Triflates
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjug Chem
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in bioelectronic sensing
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends Biotechnol
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble inflammatory Aβ-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Microfluidic diffusional sizing for studying protein-protein interactions
MM Schneider, CM Dobson, A Aguzzi, FU Hartl, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers.
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, R Cascella, A Bigi, LR Sasser, NR Block, AK Wright, RP Kreiser, ET Custy, G Meisl, S Errico, J Habchi, P Flagmeier, T Kartanas, JE Hollows, LT Nguyen, K LeForte, D Barbut, JR Kumita, C Cecchi, M Zasloff, TPJ Knowles, CM Dobson, F Chiti, M Vendruscolo
Front Neurosci
(2021)
15
(doi: 10.3389/fnins.2021.680026)
Machine learning-aided protein identification from multidimensional signatures
Y Zhang, MA Wright, KL Saar, P Challa, AS Morgunov, QAE Peter, S Devenish, CM Dobson, TPJ Knowles
Lab Chip
(2021)
21
(doi: 10.1039/d0lc01148g)
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films.
A Kamada, M Rodriguez-Garcia, FS Ruggeri, Y Shen, A Levin, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-23813-6)
Mapping the binding site topology of amyloid protein aggregates using multivalent ligands
E Sanna, M Rodrigues, SG Fagan, TS Chisholm, K Kulenkampff, D Klenerman, MG Spillantini, FI Aigbirhio, CA Hunter
Chem Sci
(2021)
12
(doi: 10.1039/d1sc01263k)
pH‐Responsive Capsules with a Fibril Scaffold Shell Assembled from an Amyloidogenic Peptide
U Shimanovich, A Levin, D Eliaz, T Michaels, Z Toprakcioglu, B Frohm, E De Genst, S Linse, KS Åkerfeldt, TPJ Knowles
Small (Weinheim an der Bergstrasse, Germany)
(2021)
17
(doi: 10.1002/smll.202007188)
Deformable and robust core-shell protein microcapsules templated by liquid-liquid phase separated microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
(2021)
(doi: 10.48550/arxiv.2009.13413)
Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells.
JC Sang, E Hidari, G Meisl, RT Ranasinghe, MG Spillantini, D Klenerman
Communications Biology
(2021)
4
(doi: 10.1038/s42003-021-02126-w)
Pulsed Hydrogen-Deuterium Exchange Reveals Altered Structures and Mechanisms in the Aggregation of Familial Alzheimer's Disease Mutants.
E Illes-Toth, G Meisl, DL Rempel, TPJ Knowles, ML Gross
ACS Chemical Neuroscience
(2021)
12
(doi: 10.1021/acschemneuro.1c00072)
DeepSinse: deep learning-based detection of single molecules.
JSH Danial, R Shalaby, K Cosentino, MM Mahmoud, F Medhat, D Klenerman, AJ Garcia Saez
Bioinformatics (Oxford, England)
(2021)
37
(doi: 10.1093/bioinformatics/btab352)
In situ Sub-Cellular Identification of Functional Amyloids in Bacteria and Archaea by Infrared Nanospectroscopy.
DE Otzen, MS Dueholm, Z Najarzadeh, TPJ Knowles, FS Ruggeri
Small Methods
(2021)
5
(doi: 10.1002/smtd.202001002)
Rapid highly sensitive general protein quantification through on-chip chemiluminescence
HK Chiu, T Kartanas, KL Saar, CM Luxhøj, S Devenish, TPJ Knowles
Biomicrofluidics
(2021)
15
(doi: 10.1063/5.0039872)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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