Centre for Experimental Biophysical Chemistry

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  • Currently displaying 421 - 440 of 1195 publications
Author(s)
Publication title
Journal Name
Publication year
Comparative Studies in the A30P and A53T α-Synuclein <i>C. elegans</i> Strains to Investigate the Molecular Origins of Parkinson's Disease.
M Perni, A van der Goot, R Limbocker, TJ van Ham, FA Aprile, CK Xu, P Flagmeier, K Thijssen, P Sormanni, G Fusco, SW Chen, PK Challa, JB Kirkegaard, RF Laine, KY Ma, MBD Müller, T Sinnige, JR Kumita, SIA Cohen, R Seinstra, GS Kaminski Schierle, CF Kaminski, D Barbut, A De Simone, TPJ Knowles, M Zasloff, EAA Nollen, M Vendruscolo, CM Dobson
Frontiers in Cell and Developmental Biology
(2021)
9
(doi: 10.3389/fcell.2021.552549)
Single molecule imaging of protein aggregation in Dementia: Methods, insights and prospects
JSH Danial, D Klenerman
Neurobiol Dis
(2021)
153
(doi: 10.1016/j.nbd.2021.105327)
Kinetic analysis reveals that independent nucleation events determine the progression of polyglutamine aggregation in C. elegans.
T Sinnige, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, RI Morimoto
Proceedings of the National Academy of Sciences
(2021)
118
(doi: 10.1073/pnas.2021888118)
Supramolecular Peptide Nanofibrils with Optimized Sequences and Molecular Structures for Efficient Retroviral Transduction
S Sieste, T Mack, E Lump, M Hayn, D Schütz, A Röcker, C Meier, K Kaygisiz, F Kirchhoff, TPJ Knowles, FS Ruggeri, CV Synatschke, J Münch, T Weil
Advanced Functional Materials
(2021)
31
(doi: 10.1002/adfm.202009382)
Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions.
G Krainer, TJ Welsh, JA Joseph, JR Espinosa, S Wittmann, E de Csilléry, A Sridhar, Z Toprakcioglu, G Gudiškytė, MA Czekalska, WE Arter, J Guillén-Boixet, TM Franzmann, S Qamar, PS George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-021-21181-9)
Single-Molecule Light-Sheet Microscopy with Local Nanopipette Delivery.
B Li, A Ponjavic, W-H Chen, L Hopkins, C Hughes, Y Ye, C Bryant, D Klenerman
Analytical chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c05296)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250)
Shear-Mediated Sol-Gel Transition of Regenerated Silk Allows the Formation of Janus-like Microgels
Z Toprakcioglu, T Knowles
(2021)
(doi: 10.26434/chemrxiv.13909250.v1)
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
One-Step Generation of Multisomes from Lipid-Stabilized Double Emulsions
MA Czekalska, AMJ Jacobs, Z Toprakcioglu, L Kong, KN Baumann, H Gang, G Zubaite, R Ye, B Mu, A Levin, WTS Huck, TPJ Knowles
ACS Appl Mater Interfaces
(2021)
13
(doi: 10.1021/acsami.0c16019)
Direct Digital Sensing of Proteins in Solution through Single-Molecule Optofluidics
G Krainer, KL Saar, WE Arter, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.2269)
Infrared Nanospectroscopy Reveals the Molecular Interaction Fingerprint of an Aggregation Inhibitor with Single Ab42 Oligomers
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nat Commun
(2021)
12
(doi: 10.1038/s41467-020-20782-0)
Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection.
T Kartanas, A Levin, Z Toprakcioglu, T Scheidt, TA Hakala, J Charmet, TPJ Knowles
Analytical chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c04149)
In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers
E Zurlo, P Kumar, G Meisl, AJ Dear, D Mondal, MMAE Claessens, TPJ Knowles, M Huber
PLoS One
(2021)
16
(doi: 10.1371/journal.pone.0245548)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-020-01490-3)
Microfluidic diffusional sizing for studying protein-protein interactions
MM Schneider, CM Dobson, A Aguzzi, FU Hartl, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2021)
50
DETECTION AND QUANTIFICATION OF IMMUNOLOGICALLY RELEVANT ALLOANTIBODY-HLA INTERACTIONS USING MICROFLUIDIC ANTIBODY AFFINITY PROFILING
A Priddey, M Schneider, G Karahan, T Scheidt, C Xu, G Meisl, H Copley, F Claas, R Buchli, A Mulder, S Heidt, T Knowles, V Kosmoliaptsis
TRANSPLANT INTERNATIONAL
(2021)
34
Single-molecule fluorescence detection of a tricyclic nucleoside analogue
GN Samaan, MK Wyllie, JM Cizmic, L-M Needham, D Nobis, K Ngo, S Andersen, SW Magennis, SF Lee, BW Purse
Chemical Science
(2020)
12
(doi: 10.1039/d0sc03903a)
Interactions of α-synuclein oligomers with lipid membranes
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et biophysica acta. Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
Yusuf Hamied Department of Chemistry
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