Centre for Experimental Biophysical Chemistry

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  • Currently displaying 501 - 520 of 1272 publications
Author(s)
Publication title
Journal Name
Publication year
Reentrant Liquid Condensate Phase of Proteins is Stabilized by Hydrophobic and Non-Ionic interactions
G Krainer, TJ Welsh, JA Joseph, P St George-Hyslop, AA Hyman, R Collepardo-Guevara, S Alberti, TPJ Knowles
Biophysical Journal
(2021)
120
(doi: 10.1016/j.bpj.2020.11.426)
Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers.
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nature Communications
(2021)
12
(doi: 10.1038/s41467-020-20782-0)
Label-Free Protein Analysis Using Liquid Chromatography with Gravimetric Detection
T Kartanas, A Levin, Z Toprakcioglu, T Scheidt, TA Hakala, J Charmet, TPJ Knowles
Analytical chemistry
(2021)
93
(doi: 10.1021/acs.analchem.0c04149)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers (vol 4, 19, 2021)
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications Biology
(2021)
4
(doi: 10.1038/s42003-021-01680-7)
In situ kinetic measurements of α-synuclein aggregation reveal large population of shortlived oligomers
E Zurlo, P Kumar, G Meisl, AJ Dear, D Mondal, MMAE Claessens, TPJ Knowles, M Huber
Plos One
(2021)
16
(doi: 10.1371/journal.pone.0245548)
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
R Cataldi, S Chia, K Pisani, FS Ruggeri, CK Xu, T Šneideris, M Perni, S Sarwat, P Joshi, JR Kumita, S Linse, J Habchi, TPJ Knowles, B Mannini, CM Dobson, M Vendruscolo
Communications biology
(2021)
4
(doi: 10.1038/s42003-020-01490-3)
Single-molecule fluorescence detection of a tricyclic nucleoside analogue
GN Samaan, MK Wyllie, JM Cizmic, L-M Needham, D Nobis, K Ngo, S Andersen, SW Magennis, SF Lee, BW Purse
Chem Sci
(2020)
12
(doi: 10.1039/d0sc03903a)
Interactions of α-synuclein oligomers with lipid membranes.
G Musteikytė, AK Jayaram, CK Xu, M Vendruscolo, G Krainer, TPJ Knowles
Biochimica et Biophysica Acta (BBA) - Biomembranes
(2020)
1863
(doi: 10.1016/j.bbamem.2020.183536)
Environmental Control of Amyloid Polymorphism by Modulation of Hydrodynamic Stress
J Zhou, L Venturelli, L Keiser, SK Sekatskii, F Gallaire, S Kasas, G Longo, TPJ Knowles, FS Ruggeri, G Dietler
ACS Nano
(2020)
15
(doi: 10.1021/acsnano.0c07570)
In vitro measurements of protein–protein interactions show that antibody affinity governs the inhibition of SARS-CoV-2 spike/ACE2 binding in convalescent serum
S Fiedler, MA Piziorska, V Denninger, AS Morgunov, A Ilsley, AY Malik, MM Schneider, SRA Devenish, G Meisl, A Aguzzi, H Fiegler, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.20.422820)
Rotavirus Replication Factories Are Complex Ribonucleoprotein Condensates
F Geiger, G Papa, WE Arter, J Acker, KL Saar, N Erkamp, R Qi, J Bravo, S Strauss, G Krainer, OR Burrone, R Jungmann, TPJ Knowles, H Engelke, A Borodavka
(2020)
(doi: 10.1101/2020.12.18.423429)
Screening of small molecules using the inhibition of oligomer formation in α-synuclein aggregation as a selection parameter
R Staats, TCT Michaels, P Flagmeier, S Chia, RI Horne, J Habchi, S Linse, TPJ Knowles, CM Dobson, M Vendruscolo
Communications Chemistry
(2020)
3
(doi: 10.1038/s42004-020-00412-y)
Physical mechanisms of amyloid nucleation on fluid membranes
J Krausser, TPJ Knowles, A Šarić
Proceedings of the National Academy of Sciences of the United States of America
(2020)
117
(doi: 10.1073/pnas.2007694117)
Correction: Correction: Multi-scale microporous silica microcapsules from gas-in water-in oil emulsions
Z Toprakcioglu, TA Hakala, A Levin, CFW Becker, GJL Bernardes, TPJ Knowles
Soft Matter
(2020)
17
(doi: 10.1039/d0sm90246b)
New solution for fast axial scanning in fluorescence microscopy.
W Zong
Light Sci Appl
(2020)
9
(doi: 10.1038/s41377-020-00442-0)
Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals
J Adamcik, FS Ruggeri, JT Berryman, A Zhang, TPJ Knowles, R Mezzenga
Advanced Science
(2020)
8
(doi: 10.1002/advs.202002182)
Construction of a liquid-liquid phase separation system from the gel-sol transition of elongated protein microgels in a crowding agent
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
(2020)
(doi: 10.1101/2020.12.08.416867)
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, while the Alzheimer’s R47H mutant does the opposite
A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, M Puigdellívol, A Bruzas, MA Burguillos, RB Dodd, F Chen, Y Zhang, P Flagmeier, L-M Needham, M Enomoto, S Qamar, J Henderson, J Walter, PE Fraser, D Klenerman, SF Lee, P St George-Hyslop, GC Brown
(2020)
(doi: 10.1101/2020.12.03.409995)
Soft Polydimethylsiloxane-Supported Lipid Bilayers for Studying T Cell Interactions
AH Lippert, IB Dimov, AK Winkel, J Humphrey, J McColl, KY Chen, AM Santos, E Jenkins, K Franze, SJ Davis, D Klenerman
Biophys J
(2020)
120
(doi: 10.1016/j.bpj.2020.11.021)
Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease
G Meisl, Y Zuo, K Allinson, T Rittman, S DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, TPJ Knowles, D Klenerman
(2020)
(doi: 10.1101/2020.11.16.384727)
Yusuf Hamied Department of Chemistry
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