Centre for Experimental Biophysical Chemistry

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  • Currently displaying 181 - 200 of 1124 publications
Author(s)
Publication title
Journal Name
Publication year
De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
M Rebelo, C Tang, AR Coelho, C Labão-Almeida, MM Schneider, L Tatalick, P Ruivo, MP de Miranda, A Gomes, T Carvalho, MJ Walker, H Ausserwoeger, J Pedro Simas, M Veldhoen, TPJ Knowles, D-A Silva, D Shoultz, GJL Bernardes
J Infect Dis
(2023)
228
(doi: 10.1093/infdis/jiad135)
Quantifying collective interactions in biomolecular phase separation
H Ausserwöger, D Qian, G Krainer, E de Csilléry, T Welsh, T Sneideris, T Franzmann, S Qamar, N Erkamp, J Nixon-Abell, M Kar, PS George-Hyslop, A Hyman, S Alberti, R Pappu, T Knowles
(2023)
(doi: 10.1101/2023.05.31.543137)
Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains
A Miller, J Wei, S Meehan, CM Dobson, ME Welland, D Klenerman, M Vendruscolo, FS Ruggeri, TPJ Knowles
Proceedings of the National Academy of Sciences of USA
(2023)
120
(doi: 10.1073/pnas.2216234120)
Theoretical and Data-Driven Approaches for Biomolecular Condensates
KL Saar, D Qian, LL Good, AS Morgunov, R Collepardo-Guevara, RB Best, TPJ Knowles
Chem Rev
(2023)
123
(doi: 10.1021/acs.chemrev.2c00586)
High-density volumetric super-resolution microscopy
S Daly, JF Fernandes, E Bruggeman, A Handa, R Peters, S Benaissa, B Zhang, J Beckwith, E Sanders, R Sims, D Klenerman, S Davis, K O’Holleran, S Lee
(2023)
(doi: 10.1101/2023.05.02.539032)
Surfaces for Study of Receptor Dynamics on T Cells.
J McColl, D Klenerman
Methods Mol Biol
(2023)
2654
(doi: 10.1007/978-1-0716-3135-5_3)
ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes.
J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, G Wang, C King, MS Fernandopulle, T Sneideris, JL Watson, VVS Pillai, W Meadows, JW Henderson, JE Chambers, JL Wagstaff, SH Williams, H Coyle, Y Lu, S Zhang, SJ Marciniak, SMV Freund, E Derivery, ME Ward, M Vendruscolo, TPJ Knowles, P St George-Hyslop
bioRxiv
(2023)
(doi: 10.1101/2023.03.22.533832)
Antigen discrimination by T cells relies on size-constrained microvillar contact
D Klenerman
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-36855-9)
Multidimensional Protein Solubility Optimization with an Ultrahigh- Throughput Microfluidic Platform
NA Erkamp, M Oeller, T Sneideris, H Ausserwoger, A Levin, TJ Welsh, R Qi, D Qian, N Lorenzen, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
Analytical Chemistry
(2023)
95
(doi: 10.1021/acs.analchem.2c05495)
Kinetic Analysis Reveals the Role of Secondary Nucleation in Regenerated Silk Fibroin Self-Assembly.
A Kamada, Z Toprakcioglu, TPJ Knowles
Biomacromolecules
(2023)
24
(doi: 10.1021/acs.biomac.2c01479)
Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum.
MM Schneider, T Scheidt, AJ Priddey, CK Xu, M Hu, G Meisl, SRA Devenish, CM Dobson, V Kosmoliaptsis, TPJ Knowles
Biosens Bioelectron
(2023)
228
(doi: 10.1016/j.bios.2023.115196)
Single-Molecule Sizing through Nanocavity Confinement
RPB Jacquat, G Krainer, QAE Peter, AN Babar, O Vanderpoorten, CK Xu, TJ Welsh, CF Kaminski, UF Keyser, JJ Baumberg, TPJ Knowles
Nano Lett
(2023)
23
(doi: 10.1021/acs.nanolett.1c04830)
Selenium Silk Nanostructured Films with Antifungal and Antibacterial Activity.
Z Toprakcioglu, EG Wiita, AK Jayaram, RC Gregory, TPJ Knowles
ACS Applied Materials & Interfaces
(2023)
15
(doi: 10.1021/acsami.2c21013)
Non-specificity fingerprints for clinical stage antibodies in solution
T Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, T Knowles
(2023)
(doi: 10.1101/2023.02.13.528263)
Characterizing protein interactions in biomolecular phase separation
H Ausserwöger, G Krainer, D Qian, T Welsh, T Sneideris, MM Schneider, G Invernizzi, TW Herling, N Lorenzen, TP Knowles
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.963)
Approximate analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.1243)
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, A Klymchenko, S Davis, E Paluch, D Klenerman, M Lew, K O’Holleran, S Lee
(2023)
(doi: 10.1101/2023.02.07.527479)
Multiphase condensates from a kinetically arrested phase transition
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
Nature communications
(2023)
14
(doi: 10.1038/s41467-023-36059-1)
Direct digital sensing of protein biomarkers in solution.
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
Nat Commun
(2023)
14
(doi: 10.1038/s41467-023-35792-x)
Designer proteins as potential therapeutic biomolecular condensates
TLC Ng, M Hoare, T Welsh, S Tomas, E Wilde, TPJ Knowles, LS Itzhaki, JR Kumita
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.568)
Yusuf Hamied Department of Chemistry
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