Centre for Experimental Biophysical Chemistry

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  • Currently displaying 1021 - 1040 of 1217 publications
Author(s)
Publication title
Journal Name
Publication year
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS Comput. Biol.
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the molecular chaperone αb-crystallin to Aβ amyloid fibrils inhibits fibril elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV MacPherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201102796)
Imaging and characterisation of the surface of live cells
D Klenerman, YE Korchev, SJ Davis
Current Opinion in Chemical Biology
(2011)
15
(doi: 10.1016/j.cbpa.2011.04.001)
Quantum Dot Photoluminescence Activation and Decay: Dark, Bright, and Reversible Populations in ZnS-Capped CdSe Nanocrystals
MA Osborne, SF Lee
ACS Nano
(2011)
5
(doi: 10.1021/nn202994w)
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
International journal of molecular sciences
(2011)
12
(doi: 10.3390/ijms12095844)
Observation of spatial propagation of amyloid assembly from single nuclei
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of native proteins and the phenomenon of amyloid formation.
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja2017703)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
J Chem Phys
(2011)
135
(doi: 10.1063/1.3608918)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608916)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Nanomechanics of functional and pathological amyloid materials.
TPJ Knowles, MJ Buehler
Nat Nanotechnol
(2011)
6
(doi: 10.1038/NNANO.2011.102)
The T Cell Receptor Triggering Apparatus Is Composed of Monovalent or Monomeric Proteins*
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, P Nilsson, DL Sleep, CM Gonçalves, SH Morgan, JH Felce, R Mahen, RA Fernandes, AM Carmo, D Klenerman, SJ Davis
J Biol Chem
(2011)
286
(doi: 10.1074/jbc.m111.219212)
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
(doi: 10.48550/arxiv.1107.1454)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
Alzheimer's & Dementia
(2011)
7
(doi: 10.1016/j.jalz.2011.09.061)
Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions.
SL Shammas, TPJ Knowles, AJ Baldwin, CE Macphee, ME Welland, CM Dobson, GL Devlin
Biophysical Journal
(2011)
100
(doi: 10.1016/j.bpj.2011.04.039)
Yusuf Hamied Department of Chemistry
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