Centre for Experimental Biophysical Chemistry

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  • Currently displaying 1081 - 1100 of 1276 publications
Author(s)
Publication title
Journal Name
Publication year
Probing small molecule binding to amyloid fibrils
AK Buell, EK Esbjörner, PJ Riss, DA White, FI Aigbirhio, G Toth, ME Welland, CM Dobson, TPJ Knowles
Phys Chem Chem Phys
(2011)
13
(doi: 10.1039/c1cp22283j)
Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation.
AW Fitzpatrick, TPJ Knowles, CA Waudby, M Vendruscolo, CM Dobson
PLoS Comput Biol
(2011)
7
(doi: 10.1371/journal.pcbi.1002169)
Binding of the Molecular Chaperone alpha B-Crystallin to A beta Amyloid Fibrils Inhibits Fibril Elongation
SL Shammas, CA Waudby, S Wang, AK Buell, TPJ Knowles, H Ecroyd, ME Welland, JA Carver, CM Dobson, S Meehan
Biophysical Journal
(2011)
101
(doi: 10.1016/j.bpj.2011.07.056)
Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV MacPherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
Angewandte Chemie International Edition
(2011)
50
(doi: 10.1002/anie.201102796)
Imaging and characterisation of the surface of live cells
D Klenerman, YE Korchev, SJ Davis
Current Opinion in Chemical Biology
(2011)
15
(doi: 10.1016/j.cbpa.2011.04.001)
Quantum dot photoluminescence activation and decay: dark, bright, and reversible populations in ZnS-capped CdSe nanocrystals.
MA Osborne, SF Lee
ACS nano
(2011)
5
(doi: 10.1021/nn202994w)
Nucleated polymerisation in the presence of pre-formed seed filaments.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
Int J Mol Sci
(2011)
12
(doi: 10.3390/ijms12095844)
Observation of spatial propagation of amyloid assembly from single nuclei.
TPJ Knowles, DA White, AR Abate, JJ Agresti, SIA Cohen, RA Sperling, EJ De Genst, CM Dobson, DA Weitz
Proceedings of the National Academy of Sciences of the United States of America
(2011)
108
(doi: 10.1073/pnas.1105555108)
Metastability of Native Proteins and the Phenomenon of Amyloid Formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, SL Shammas, CA Waudby, MF Mossuto, S Meehan, SL Gras, J Christodoulou, SJ Anthony-Cahill, PD Barker, M Vendruscolo, CM Dobson
J Am Chem Soc
(2011)
133
(doi: 10.1021/ja2017703)
Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
The Journal of Chemical Physics
(2011)
135
(doi: 10.1063/1.3608917)
Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
SIA Cohen, M Vendruscolo, ME Welland, CM Dobson, EM Terentjev, TPJ Knowles
The Journal of chemical physics
(2011)
135
(doi: 10.1063/1.3608916)
Nucleated polymerization with secondary pathways. III. Equilibrium behavior and oligomer populations.
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
J Chem Phys
(2011)
135
(doi: 10.1063/1.3608918)
Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein
K Levitan, D Chereau, SIA Cohen, TPJ Knowles, CM Dobson, AL Fink, JP Anderson, JM Goldstein, GL Millhauser
Journal of Molecular Biology
(2011)
411
(doi: 10.1016/j.jmb.2011.05.046)
Kinetics of protein aggregation
T Knowles, M Vendruscolo, C Dobson
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Direct observation of the interconversion of normal and pathogenic forms of α-synuclein
N Cremades, SIA Cohen, AY Chen, A Orte, M Sandal, RW Clarke, P Dunne, FA Aprile, CW Bertoncini, TPJ Knowles, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2011)
40
Nanomechanics of functional and pathological amyloid materials
TPJ Knowles, MJ Buehler
Nat Nanotechnol
(2011)
6
(doi: 10.1038/nnano.2011.102)
The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins
JR James, J McColl, MI Oliveira, PD Dunne, E Huang, A Jansson, P Nilsson, DL Sleep, CM Gonçalves, SH Morgan, JH Felce, R Mahen, RA Fernandes, AM Carmo, D Klenerman, SJ Davis
Journal of Biological Chemistry
(2011)
286
(doi: 10.1074/jbc.m111.219212)
Nucleated polymerisation in the presence of pre-formed seed filaments
SIA Cohen, M Vendruscolo, CM Dobson, TPJ Knowles
(2011)
(doi: 10.48550/arxiv.1107.1454)
P4‐316: Stabilization of neurotoxic Alzheimer amyloid‐beta oligomers by protein engineering
A Dubnovitsky, A Sandberg, L Luheshi, S Söllvander, TP de Barros, B Macao, T Knowles, H Biverstål, C Lendel, F Ekholm‐Petterson, L Lannfelt, C Dobson, T Härd
Alzheimer's & Dementia
(2011)
7
(doi: 10.1016/j.jalz.2011.09.061)
Perturbation of the stability of amyloid fibrils through alteration of electrostatic interactions
SL Shammas, TPJ Knowles, AJ Baldwin, CE Macphee, ME Welland, CM Dobson, GL Devlin
Biophys J
(2011)
100
(doi: 10.1016/j.bpj.2011.04.039)
Yusuf Hamied Department of Chemistry
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