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Currently displaying 981 - 1000 of 1276 publications

ChemInform Abstract: Protein Micro‐ and Nano‐Capsules for Biomedical Applications

U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco‐Paulo

ChemInform

(2014)

(doi: 10.1002/chin.201418286)

Rare Individual Amyloid‑β Oligomers Act on Astrocytes to Initiate Neuronal Damage

P Narayan, KM Holmström, D-H Kim, DJ Whitcomb, MR Wilson, P St George-Hyslop, NW Wood, CM Dobson, K Cho, AY Abramov, D Klenerman

Biochemistry

(2014)

2442

(doi: 10.1021/bi401606f)

Density-gradient-free microfluidic centrifugation for analytical and preparative separation of nanoparticles

P Arosio, T Müller, L Mahadevan, TPJ Knowles

Nano Letters

(2014)

2365

(doi: 10.1021/nl404771g)

Nucleation-conversion-polymerization reactions of biological macromolecules with prenucleation clusters

GA Garcia, SIA Cohen, CM Dobson, TPJ Knowles

Physical Review E

(2014)

032712

(doi: 10.1103/physreve.89.032712)

Nucleation-conversion-polymerization reactions of biological macromolecules with prenucleation clusters

GA Garcia, SIA Cohen, CM Dobson, TPJ Knowles

Physical Review E

(2014)

032712

(doi: 10.1103/PhysRevE.89.032712)

Quantitative sensing of microviscosity in protocells and amyloid materials using fluorescence lifetime imaging of molecular rotors

AJ Thompson, T-YD Tang, TW Herling, CRC Hak, S Mann, TPJ Knowles, MK Kuimova

Progress in Biomedical Optics and Imaging Proceedings of SPIE

(2014)

8947

89471C

(doi: 10.1117/12.2037851)

Spatial propagation of protein polymerization.

SIA Cohen, L Rajah, CH Yoon, AK Buell, DA White, RA Sperling, M Vendruscolo, EM Terentjev, CM Dobson, DA Weitz, TPJ Knowles

Physical Review Letters

(2014)

112

098101

(doi: 10.1103/PhysRevLett.112.098101)

Contact-free scanning and imaging with the scanning ion conductance microscope

S Del Linz, E Willman, M Caldwell, D Klenerman, A Fernández, G Moss

Analytical Chemistry

(2014)

2353

(doi: 10.1021/ac402748j)

Chemical kinetics for drug discovery to combat protein aggregation diseases

P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles

Trends in Pharmacological Sciences

(2014)

127

(doi: 10.1016/j.tips.2013.12.005)

A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging.

L Bell, A Seshia, D Lando, E Laue, M Palayret, SF Lee, D Klenerman

Sensors and Actuators B Chemical

(2014)

192

(doi: 10.1016/j.snb.2013.10.002)

The role of stable α-synuclein oligomers in the molecular events underlying amyloid formation

N Lorenzen, SB Nielsen, AK Buell, JD Kaspersen, P Arosio, BS Vad, W Paslawski, G Christiansen, Z Valnickova-Hansen, M Andreasen, JJ Enghild, JS Pedersen, CM Dobson, TPJ Knowles, DE Otzen

Journal of the American Chemical Society

(2014)

136

3859

(doi: 10.1021/ja411577t)

Imaging Single Nanoparticle Interactions with Human Lung Cells Using Fast Ion Conductance Microscopy

P Novak, A Shevchuk, P Ruenraroengsak, M Miragoli, AJ Thorley, D Klenerman, MJ Lab, TD Tetley, J Gorelik, YE Korchev

Nano Lett

(2014)

1202

(doi: 10.1021/nl404068p)

Label-free measurements of the diffusivity of molecules in lipid membranes

B Johansson, F Höök, D Klenerman, P Jönsson

Chemphyschem

(2014)

486

(doi: 10.1002/cphc.201301136)

Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide

B Bolognesi, SIA Cohen, P Aran Terol, EK Esbjörner, S Giorgetti, MF Mossuto, A Natalello, AC Brorsson, TPJ Knowles, CM Dobson, LM Luheshi

ACS Chemical Biology

(2014)

378

(doi: 10.1021/cb400616y)

Diffuse transition state structure for the unfolding of a leucine-rich repeat protein

SE Kelly, G Meisl, PJE Rowling, SH McLaughlin, T Knowles, LS Itzhaki

Physical Chemistry Chemical Physics

(2014)

6448

(doi: 10.1039/c3cp54818j)

Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson's Disease

G Tóth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, MA Tambe, J-C Rochet, C Galvagnion, G Skibinski, S Finkbeiner, M Bova, K Regnstrom, S-S Chiou, J Johnston, K Callaway, JP Anderson, MF Jobling, AK Buell, TA Yednock, TPJ Knowles, M Vendruscolo, J Christodoulou, CM Dobson, D Schenk, L McConlogue

Plos One

(2014)

e87133

(doi: 10.1371/journal.pone.0087133)