Centre for Experimental Biophysical Chemistry

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  • Currently displaying 961 - 980 of 1301 publications
Author(s)
Publication title
Journal Name
Publication year
Aggregation‐Prone Amyloid‐β⋅CuII Species Formed on the Millisecond Timescale under Mildly Acidic Conditions
JT Pedersen, CB Borg, TCT Michaels, TPJ Knowles, P Faller, K Teilum, L Hemmingsen
Chembiochem : a European journal of chemical biology
(2015)
16
(doi: 10.1002/cbic.201500080)
The Aβ40 and Aβ42 peptides self-assemble into separate homomolecular fibrils in binary mixtures but cross-react during primary nucleation
R Cukalevski, X Yang, G Meisl, U Weininger, K Bernfur, B Frohm, TPJ Knowles, S Linse
Chemical Science
(2015)
6
(doi: 10.1039/c4sc02517b)
A mechanistic model of tau amyloid aggregation based on direct observation of oligomers.
SL Shammas, GA Garcia, S Kumar, M Kjaergaard, MH Horrocks, N Shivji, E Mandelkow, TPJ Knowles, E Mandelkow, D Klenerman
Nat Commun
(2015)
6
(doi: 10.1038/ncomms8025)
Preventing peptide and protein misbehavior
P Arosio, G Meisl, M Andreasen, TPJ Knowles
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1505170112)
Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation
SW Chen, S Drakulic, E Deas, M Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, EJ De-Genst, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112)
Structural characterization of toxic oligomers that are kinetically trapped during alpha-synuclein fibril formation
SW Chen, S Drakulic, E Deas, MM Ouberai, FA Aprile, R Arranz, S Ness, C Roodveldt, T Guilliams, GE De, D Klenerman, NW Wood, TPJ Knowles, C Alfonso, G Rivas, AY Abramov, JM Valpuesta, CM Dobson, N Cremades
Proceedings of the National Academy of Sciences
(2015)
112
(doi: 10.1073/pnas.1421204112.)
PO-0782: Breast radiotherapy: invisible tattoos for external references (The BRITER study)
S Landeg, AM Kirby, S Lee, F Bartlett, E Donovan, I Locke, L Gothard, S Boyle, K Titmarsh, C Griffin, H McNair
Radiotherapy and Oncology
(2015)
115
(doi: 10.1016/s0167-8140(15)40774-1)
Breast radiotherapy: invisible tattoos for external references (The BRITER study)
S Landeg, AM Kirby, S Lee, F Bartlett, E Donovan, I Locke, L Gothard, S Boyle, K Titmarsh, C Griffin, H McNair
RADIOTHERAPY AND ONCOLOGY
(2015)
115
On-demand delivery of single DNA molecules using nanopipets.
AP Ivanov, P Actis, P Jönsson, D Klenerman, Y Korchev, JB Edel
ACS nano
(2015)
9
(doi: 10.1021/acsnano.5b00911)
Lipid peroxidation is essential for α-synuclein-induced cell death
PR Angelova, MH Horrocks, D Klenerman, S Gandhi, AY Abramov, MS Shchepinov
Journal of Neurochemistry
(2015)
133
(doi: 10.1111/jnc.13024)
A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
SIA Cohen, P Arosio, J Presto, FR Kurudenkandy, H Biverstål, L Dolfe, C Dunning, X Yang, B Frohm, M Vendruscolo, J Johansson, CM Dobson, A Fisahn, TPJ Knowles, S Linse
Nature Structural and Molecular Biology
(2015)
22
(doi: 10.1038/nsmb.2971)
The physical basis of protein misfolding disorders
TPJ Knowles, M Vendruscolo, CM Dobson
Physics Today
(2015)
68
(doi: 10.1063/PT.3.2719)
SICM-Based Nanodelivery System for Local TRPV1 Stimulation
A López-Córdoba, P Jönsson, B Babakinejad, P Actis, P Novak, T Yasufumi, A Shevchuck, U Anand, P Anand, A Drews, A Ferrer-Montiel, D Klenerman, Y Korchev
Biophysical Journal
(2015)
108
(doi: 10.1016/j.bpj.2014.11.1808)
Protein microgels from amyloid fibril networks.
U Shimanovich, I Efimov, TO Mason, P Flagmeier, AK Buell, A Gedanken, S Linse, KS Åkerfeldt, CM Dobson, DA Weitz, TPJ Knowles
ACS nano
(2015)
9
(doi: 10.1021/nn504869d)
Single-Molecule FRET Reveals Hidden Complexity in a Protein Energy Landscape
M Tsytlonok, SM Ibrahim, PJE Rowling, W Xu, MJ Ruedas-Rama, A Orte, D Klenerman, LS Itzhaki
Structure (London, England : 1993)
(2015)
23
(doi: 10.1016/j.str.2014.10.023)
A microfluidic platform for quantitative measurements of effective protein charges and single ion binding in solution.
TW Herling, P Arosio, T Müller, S Linse, TPJ Knowles
Physical chemistry chemical physics : PCCP
(2015)
17
(doi: 10.1039/c5cp00746a)
On the lag phase in amyloid fibril formation.
P Arosio, TPJ Knowles, S Linse
Phys Chem Chem Phys
(2015)
17
(doi: 10.1039/c4cp05563b)
Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging
M Palayret, H Armes, S Basu, AT Watson, A Herbert, D Lando, TJ Etheridge, U Endesfelder, M Heilemann, E Laue, AM Carr, D Klenerman, SF Lee
PloS one
(2015)
10
(doi: 10.1371/journal.pone.0125438)
Biophysical approaches for the study of interactions between molecular chaperones and protein aggregates.
MA Wright, FA Aprile, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Chem Commun (Camb)
(2015)
51
(doi: 10.1039/c5cc03689e)
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, TPJ Knowles, CM Dobson
Nature Chemical Biology
(2015)
11
(doi: 10.1038/nchembio.1750)
Yusuf Hamied Department of Chemistry
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enquiries@ch.cam.ac.uk
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