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  • Currently displaying 101 - 120 of 1146 publications
Author(s)
Publication title
Journal Name
Publication year
Serine phosphorylation mimics of Aβ form distinct, non-cross-seeding fibril morphs.
K Sanagavarapu, G Meisl, V Lattanzi, K Bernfur, B Frohm, U Olsson, TPJ Knowles, A Malmendal, S Linse
Chem Sci
(2024)
15
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O'Holleran, SF Lee
Nature Methods
(2024)
21
Biomolecular Condensates are Characterized by Interphase Electric Potentials.
AE Posey, A Bremer, NA Erkamp, A Pant, TPJ Knowles, Y Dai, T Mittag, RV Pappu
J Am Chem Soc
(2024)
146
Aggregation of the amyloid-β peptide (Aβ40) within condensates generated through liquid–liquid phase separation
OM Morris, Z Toprakcioglu, A Röntgen, M Cali, TPJ Knowles, M Vendruscolo
Scientific Reports
(2024)
14
Mechanical Profiling of Biopolymer Condensates through Acoustic Trapping.
K Nakajima, T Sneideris, LL Good, NA Erkamp, H Ogi, TPJ Knowles
(2024)
Single-molecule digital sizing of proteins in solution
G Krainer, RPB Jacquat, MM Schneider, TJ Welsh, J Fan, QAE Peter, EA Andrzejewska, G Šneiderienė, MA Czekalska, H Ausserwoeger, L Chai, WE Arter, KL Saar, TW Herling, TM Franzmann, V Kosmoliaptsis, S Alberti, FU Hartl, SF Lee, TPJ Knowles
Nature communications
(2024)
15
A human neuronal model of sporadic Alzheimer’s disease induced by FBXO2 downregulation shows Aβ aggregation, tau hyperphosphorylation and functional network impairment
AG Díaz, A Possenti, GA Urrutia, Y Bian, S Kedia, D Boeken, C Lim, D Licastro, B Mannini, D Klenerman, M Vendruscolo
(2024)
Hyaluronidase unlocks sequestered CEACAM5 and improves CAR T-cell therapy in colorectal cancer
D Banik, C Ward, Z Zhang, S Chakraborty, D Heraghty, P Suresh, B Li, S Kedia, S Davis, J Roy, M Chapman, B Mahata, D Klenerman
(2024)
Unraveling the Structure and Dynamics of Ac-PHF6-NH<sub>2</sub> Tau Segment Oligomers.
I Stroganova, Z Toprakcioglu, H Willenberg, TPJ Knowles, AM Rijs
ACS Chem Neurosci
(2024)
15
Aggregate-selective removal of pathological tau by clustering-activated degraders.
J Benn, S Cheng, S Keeling, AE Smith, MJ Vaysburd, D Böken, LVC Miller, T Katsinelos, C Franco, E Dupré, C Danis, I Landrieu, L Buée, D Klenerman, LC James, WA McEwan
Science (New York, N.Y.)
(2024)
385
Surface effects on functional amyloid formation.
AJ Dear, G Meisl, CG Taylor, UC Palmiero, SN Stubbe, Q Liu, P Arosio, S Linse, TPJ Knowles, M Andreasen
Nanoscale
(2024)
16
SynPull: a novel method for studying neurodegeneration-related aggregates in synaptosomes using super-resolution microscopy
S Kedia, E Fertan, Y Wu, YP Zhang, G Meisl, JYL Lam, F Wiseman, WA McEwan, A Quaegebeur, MG Spillantini, JSH Danial, D Klenerman
(2024)
Formation of Nanofibrillar Self-Healing Hydrogels Using Antimicrobial Peptides.
EG Wiita, Z Toprakcioglu, AK Jayaram, TPJ Knowles
ACS Applied Materials and Interfaces
(2024)
16
Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates
NA Erkamp, M Farag, Y Qiu, D Qian, T Sneideris, T Wu, TJ Welsh, H Ausserwӧger, TJ Krug, DA Weitz, M Lew, TPJ Knowles, RV Pappu
(2024)
a-Synuclein oligomers form by secondary nucleation
CK Xu, G Meisl, EA Andrzejewska, G Krainer, AJ Dear, M Castellana-Cruz, S Turi, IA Edu, G Vivacqua, RPB Jacquat, WE Arter, MG Spillantini, M Vendruscolo, S Linse, TPJ Knowles
Nat Commun
(2024)
15
Competing addition processes give distinct growth regimes in the assembly of 1D filaments
SA Akram, T Brown, S Whitelam, G Meisl, TPJ Knowles, JD Schmit
(2024)
Dominance analysis to assess solute contributions to multicomponent phase equilibria.
D Qian, H Ausserwoger, T Sneideris, M Farag, RV Pappu, TPJ Knowles
Proceedings of the National Academy of Sciences of the United States of America
(2024)
121
Assessment of Fine-Tuned Large Language Models for Real-World Chemistry and Material Science Applications
J van Herck, MV Gil, KM Jablonka, A Abrudan, A Anker, M Asgari, B Blaiszik, L Choudhury, C Corminboeuf, H Daglar, IT Foster, S Garcia, M Garvin, G Godin, LL Good, J Gu, NX Hu, X Jin, T Junkers, S Keskin, TPJ Knowles, R Laplaza, S Majumdar, H Mashhadimoslem, RD McIntosh, SM Moosavi, B Mourino, F Nerli, C Pevida, N Poudineh, M Rajabi-Kochi, KL Saar, FH Saboor, M Sagharichiha, KJ Schmidt, J Shi, D Svatunek, M Taddei, I Tetko, D Tolnai, S Vahdatifar, J Whitmer, F Wieland, R Willumeit-Romer, A Zuttel, B Smit
(2024)
Molecular properties and diagnostic potential of monoclonal antibodies targeting cytotoxic α-synuclein oligomers
J Nielsen, J Lauritsen, JN Pedersen, JS Nowak, MK Bendtsen, G Kleijwegt, K Lusser, LC Pitarch, JV Moreno, MM Schneider, G Krainer, L Goksøyr, P Khalifé, SS Kaalund, S Aznar, M Kjærgaard, V Sereikaité, K Strømgaard, TPJ Knowles, MA Nielsen, AF Sander, M Romero-Ramos, DE Otzen
NPJ Parkinson's disease
(2024)
10
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist
B Zhang, S Daly, C Zhu, M Lenz, L Weiss, L-M Needham, R Peters, S Lee, K O’Holleran
(2024)