Centre for Experimental Biophysical Chemistry

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  • Currently displaying 901 - 920 of 1210 publications
Author(s)
Publication title
Journal Name
Publication year
Single-Molecule Imaging Reveals that Small Amyloid-β1-42 Oligomers Interact with the Cellular Prion Protein (PrPC)
KA Ganzinger, P Narayan, SS Qamar, L Weimann, RT Ranasinghe, A Aguzzi, CM Dobson, J McColl, P St George-Hyslop, D Klenerman
Chembiochem
(2014)
15
(doi: 10.1002/cbic.201402377)
Interaction of the Molecular Chaperone DNAJB6 with Growing Arnyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
C Månsson, P Arosio, R Hussein, HH Kampinga, RM Hashem, WC Boelens, CM Dobson, TPJ Knowles, S Linse, C Emanuelsson
J Biol Chem
(2014)
289
(doi: 10.1074/jbc.M114.595124)
Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules.
RR Murphy, G Danezis, MH Horrocks, SE Jackson, D Klenerman
Anal Chem
(2014)
86
(doi: 10.1021/ac501188r)
The physical chemistry of the amyloid phenomenon: Thermodynamics and kinetics of fi lamentous protein aggregation
AK Buell, CM Dobson, TPJ Knowles
Essays Biochem
(2014)
56
(doi: 10.1042/bse0560011)
Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy.
TJ Etheridge, RL Boulineau, A Herbert, AT Watson, Y Daigaku, J Tucker, S George, P Jönsson, M Palayret, D Lando, E Laue, MA Osborne, D Klenerman, SF Lee, AM Carr
Nucleic Acids Res
(2014)
42
(doi: 10.1093/nar/gku726)
Easyworm: An open-source software tool to determine the mechanical properties of worm-like chains
G Lamour, JB Kirkegaard, H Li, TP Knowles, J Gsponer
Source code for biology and medicine
(2014)
9
(doi: 10.1186/1751-0473-9-16)
Corrigendum: Multifunctional Nanoprobes for Nanoscale Chemical Imaging and Localized Chemical Delivery at Surfaces and Interfaces
Y Takahashi, AI Shevchuk, P Novak, Y Zhang, N Ebejer, JV Macpherson, PR Unwin, AJ Pollard, D Roy, CA Clifford, H Shiku, T Matsue, D Klenerman, YE Korchev
Angewandte Chemie International Edition
(2014)
53
(doi: 10.1002/anie.201404979)
Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides.
G Meisl, X Yang, E Hellstrand, B Frohm, JB Kirkegaard, SIA Cohen, CM Dobson, S Linse, TPJ Knowles
Proceedings of the National Academy of Sciences
(2014)
111
(doi: 10.1073/pnas.1401564111)
Self‐Assembly of Amyloid Fibrils That Display Active Enzymes
X Zhou, A Entwistle, H Zhang, AP Jackson, TO Mason, U Shimanovich, TPJ Knowles, AT Smith, EB Sawyer, S Perrett
ChemCatChem
(2014)
6
(doi: 10.1002/cctc.201402125)
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization.
TCT Michaels, TPJ Knowles
The Journal of chemical physics
(2014)
140
(doi: 10.1063/1.4880121)
The amyloid state and its association with protein misfolding diseases
TPJ Knowles, M Vendruscolo, CM Dobson
Nature reviews. Molecular cell biology
(2014)
15
(doi: 10.1038/nrm3810)
Asymptotic solutions of the Oosawa model for the length distribution of biofilaments.
TCT Michaels, GA Garcia, TPJ Knowles
The Journal of Chemical Physics
(2014)
140
(doi: 10.1063/1.4875897)
Solution conditions determine the relative importance of nucleation and growth processes in α-synuclein aggregation.
AK Buell, C Galvagnion, R Gaspar, E Sparr, M Vendruscolo, TPJ Knowles, S Linse, CM Dobson
Proceedings of the National Academy of Sciences of the United States of America
(2014)
111
(doi: 10.1073/pnas.1315346111)
Mean-field master equation formalism for biofilament growth
TCT Michaels, TPJ Knowles
American Journal of Physics
(2014)
82
(doi: 10.1119/1.4870004)
ChemInform Abstract: Protein Micro‐ and Nano‐Capsules for Biomedical Applications
U Shimanovich, GJL Bernardes, TPJ Knowles, A Cavaco‐Paulo
ChemInform
(2014)
45
(doi: 10.1002/chin.201418286)
Rare Individual Amyloid‑β Oligomers Act on Astrocytes to Initiate Neuronal Damage
P Narayan, KM Holmström, D-H Kim, DJ Whitcomb, MR Wilson, P St George-Hyslop, NW Wood, CM Dobson, K Cho, AY Abramov, D Klenerman
Biochemistry
(2014)
53
(doi: 10.1021/bi401606f)
Density-Gradient-Free Microfluidic Centrifugation for Analytical and Preparative Separation of Nanoparticles
P Arosio, T Müller, L Mahadevan, TPJ Knowles
Nano Lett
(2014)
14
(doi: 10.1021/nl404771g)
Nucleation-conversion-polymerization reactions of biological macromolecules with prenucleation clusters
GA Garcia, SIA Cohen, CM Dobson, TPJ Knowles
Physical Review E
(2014)
89
(doi: 10.1103/PhysRevE.89.032712)
Contact-free scanning and imaging with the scanning ion conductance microscope
S Del Linz, E Willman, M Caldwell, D Klenerman, A Fernández, G Moss
Analytical Chemistry
(2014)
86
(doi: 10.1021/ac402748j)
Spatial Propagation of Protein Polymerization
SIA Cohen, L Rajah, CH Yoon, AK Buell, DA White, RA Sperling, M Vendruscolo, EM Terentjev, CM Dobson, DA Weitz, TPJ Knowles
Physical review letters
(2014)
112
(doi: 10.1103/physrevlett.112.098101)
Yusuf Hamied Department of Chemistry
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