Centre for Experimental Biophysical Chemistry

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  • Currently displaying 821 - 840 of 1128 publications
Author(s)
Publication title
Journal Name
Publication year
The Role of Stable α-Synuclein Oligomers in the Molecular Events Underlying Amyloid Formation
N Lorenzen, SB Nielsen, AK Buell, JD Kaspersen, P Arosio, BS Vad, W Paslawski, G Christiansen, Z Valnickova-Hansen, M Andreasen, JJ Enghild, JS Pedersen, CM Dobson, TPJ Knowles, DE Otzen
J Am Chem Soc
(2014)
136
(doi: 10.1021/ja411577t)
Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy.
P Novak, A Shevchuk, P Ruenraroengsak, M Miragoli, AJ Thorley, D Klenerman, MJ Lab, TD Tetley, J Gorelik, YE Korchev
Nano Lett
(2014)
14
(doi: 10.1021/nl404068p)
Label-free measurements of the diffusivity of molecules in lipid membranes
B Johansson, F Höök, D Klenerman, P Jönsson
Chemphyschem
(2014)
15
(doi: 10.1002/cphc.201301136)
Single point mutations induce a switch in the molecular mechanism of the aggregation of the Alzheimer's disease associated Aβ42 peptide
B Bolognesi, SIA Cohen, P Aran Terol, EK Esbjörner, S Giorgetti, MF Mossuto, A Natalello, AC Brorsson, TPJ Knowles, CM Dobson, LM Luheshi
ACS Chemical Biology
(2014)
9
(doi: 10.1021/cb400616y)
Chemical kinetics for drug discovery to combat protein aggregation diseases.
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Trends in Pharmacological Sciences
(2014)
35
(doi: 10.1016/j.tips.2013.12.005)
Diffuse transition state structure for the unfolding of a leucine-rich repeat protein
SE Kelly, G Meisl, PJE Rowling, SH McLaughlin, T Knowles, LS Itzhaki
Physical chemistry chemical physics : PCCP
(2014)
16
(doi: 10.1039/c3cp54818j)
Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein by Small Molecules as a Potential Therapeutic Strategy for Parkinson’s Disease
G Tóth, SJ Gardai, W Zago, CW Bertoncini, N Cremades, SL Roy, MA Tambe, J-C Rochet, C Galvagnion, G Skibinski, S Finkbeiner, M Bova, K Regnstrom, S-S Chiou, J Johnston, K Callaway, JP Anderson, MF Jobling, AK Buell, TA Yednock, TPJ Knowles, M Vendruscolo, J Christodoulou, CM Dobson, D Schenk, L McConlogue
PLoS One
(2014)
9
(doi: 10.1371/journal.pone.0087133)
Contact-free scanning and imaging with the scanning ion conductance microscope
S Del Linz, E Willman, M Caldwell, D Klenerman, A Fernández, G Moss
Analytical chemistry
(2014)
86
(doi: 10.1021/ac402748j)
The changing point-spread function: single-molecule-based super-resolution imaging
MH Horrocks, M Palayret, D Klenerman, SF Lee
Histochem Cell Biol
(2014)
141
(doi: 10.1007/s00418-014-1186-1)
Quantitative Analysis of Diffusive Reactions at the Solid-Liquid Interface in Finite Systems.
TCT Michaels, AK Buell, EM Terentjev, TPJ Knowles
J Phys Chem Lett
(2014)
5
(doi: 10.1021/jz4024833)
Nanoscale spatially resolved infrared spectra from single microdroplets
T Müller, FS Ruggeri, AJ Kulik, U Shimanovich, TO Mason, TPJ Knowles, G Dietler
(2014)
(doi: 10.48550/arxiv.1401.8204)
Expanding the solvent chemical space for self-assembly of dipeptide nanostructures.
TO Mason, DY Chirgadze, A Levin, L Adler-Abramovich, E Gazit, TPJ Knowles, AK Buell
ACS Nano
(2014)
2
(doi: 10.1021/nn404237f)
Electrochemical nanoprobes for single-cell analysis.
P Actis, S Tokar, J Clausmeyer, B Babakinejad, S Mikhaleva, R Cornut, Y Takahashi, A López Córdoba, P Novak, AI Shevchuck, JA Dougan, SG Kazarian, PV Gorelkin, AS Erofeev, IV Yaminsky, PR Unwin, W Schuhmann, D Klenerman, DA Rusakov, EV Sviderskaya, YE Korchev
ACS nano
(2014)
8
(doi: 10.1021/nn405612q)
Label‐Free Measurements of the Diffusivity of Molecules in Lipid Membranes
B Johansson, F Höök, D Klenerman, P Jönsson
Chemphyschem
(2014)
15
(doi: 10.1002/cphc.201301136)
Amyloid β-Protein: The Influence of Intrinsic and Extrinsic Factors on Fibril Formation
R Cukalevski, X Yang, S Cohen, B Boland, B Frohm, E Thulin, D Walsh, T Knowles, S Linse
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3778)
Determination of Primary Nucleation Mechanisms of α-Synuclein Amyloid Aggregation
FA Aprile, G Meisl, AK Buell, P Flagmeier, CM Dobson, M Vendruscolo, TPJ Knowles
BIOPHYSICAL JOURNAL
(2014)
106
Single Molecule Fluorescence Studies of Protein Aggregates and their role in Neurodegenerative Disease
D Klenerman
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.067)
Single-Molecule Characterisation of Alpha-Synuclein Oligomers
MH Horrocks, SF Lee, S Gandhi, M Iljina, L Tosatto, CM Dobson, D Klenerman
BIOPHYSICAL JOURNAL
(2014)
106
Improved Super-Resolution Imaging in Heavy Water
A Fuerstenberg, U Endesfelder, M Heilemann, K Klehs, SF Lee, S Malkusch, C Spahn, Q Verolet
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.2251)
Insights into the Inhibition Mechanism of Biomolecular Self-Assembly from Chemical Kinetics
P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biophysical Journal
(2014)
106
(doi: 10.1016/j.bpj.2013.11.3776)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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