Centre for Experimental Biophysical Chemistry

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  • Currently displaying 801 - 820 of 1210 publications
Author(s)
Publication title
Journal Name
Publication year
Protein Aggregate‐Ligand Binding Assays Based on Microfluidic Diffusional Separation
Y Zhang, AK Buell, T Müller, E De Genst, J Benesch, CM Dobson, TPJ Knowles
Chembiochem
(2016)
17
(doi: 10.1002/cbic.201600384)
Individual aggregates of amyloid beta induce temporary calcium influx through the cell membrane of neuronal cells
A Drews, J Flint, N Shivji, P Jönsson, D Wirthensohn, E De Genst, C Vincke, S Muyldermans, C Dobson, D Klenerman
Scientific Reports
(2016)
6
(doi: 10.1038/srep31910)
Controlling the Physical Dimensions of Peptide Nanotubes by Supramolecular Polymer Coassembly
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, A Levin, DJ Scurr, CJ Roberts, TPJ Knowles, SJB Tendler, E Gazit
ACS nano
(2016)
10
(doi: 10.1021/acsnano.6b01587)
Synthesis of Nonequilibrium Supramolecular Peptide Polymers on a Microfluidic Platform
TO Mason, TCT Michaels, A Levin, E Gazit, CM Dobson, AK Buell, TPJ Knowles
J Am Chem Soc
(2016)
138
(doi: 10.1021/jacs.6b04136)
The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules
W Zhang, A Aubert, JM Gomez de Segura, M Karuppasamy, S Basu, A Murthy, A Diamante, TA Drury, J Balmer, J Cramard, AA Watson, D Lando, SF Lee, M Palayret, S Kloet, A Smits, M Deery, M Vermeulen, B Hendrich, D Klenerman, C Schaffitzel, I Berger, ED Laue
Journal of molecular biology
(2016)
428
(doi: 10.1016/j.jmb.2016.04.025)
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, CM Dobson, D Frenkel, TPJ Knowles, D Klenerman
Sci Rep
(2016)
6
(doi: 10.1038/srep28658)
Quantifying Measurement Fluctuations from Stochastic Surface Processes on Sensors with Heterogeneous Sensitivity
J Charmet, TCT Michaels, R Daly, A Prasad, P Thiruvenkathanathan, RS Langley, TPJ Knowles, AA Seshia
Physical Review Applied
(2016)
5
(doi: 10.1103/physrevapplied.5.064016)
Fluctuations in the Kinetics of Linear Protein Self-Assembly
TCT Michaels, AJ Dear, JB Kirkegaard, KL Saar, DA Weitz, TPJ Knowles
Phys Rev Lett
(2016)
116
(doi: 10.1103/physrevlett.116.258103)
Studying the Dynamics of Chromatin-Binding Proteins in Mammalian Cells Using Single-Molecule Localisation Microscopy.
S Basu, YL Tan, EJR Taylor, ED Laue, SF Lee
Methods Mol Biol
(2016)
1431
(doi: 10.1007/978-1-4939-3631-1_17)
Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers
T Müller, P Arosio, L Rajah, SIA Cohen, EV Yates, M Vendruscolo, CM Dobson, TPJ Knowles
International Journal of Nonlinear Sciences and Numerical Simulation
(2016)
17
(doi: 10.1515/ijnsns-2015-0056)
Angular Approach Scanning Ion Conductance Microscopy.
A Shevchuk, S Tokar, S Gopal, JL Sanchez-Alonso, AI Tarasov, AC Vélez-Ortega, C Chiappini, P Rorsman, MM Stevens, J Gorelik, GI Frolenkov, D Klenerman, YE Korchev
Biophysical Journal
(2016)
110
(doi: 10.1016/j.bpj.2016.04.017)
The remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions
P Jönsson, J Southcombe, AM Santos, J Huo, RA Fernandes, J McColl, M Lever, EJ Evans, A Hudson, VT Chang, T Hanke, A Godkin, PD Dunne, MH Horrocks, M Palayret, GR Screaton, J Petersen, J Rossjohn, L Fugger, O Dushek, X Xu, SJ Davis, D Klenerman
Proceedings of the National Academy of Sciences
(2016)
113
(doi: 10.1073/pnas.1513918113)
Ca2+ is a key factor in α-synuclein-induced neurotoxicity.
PR Angelova, MHR Ludtmann, MH Horrocks, A Negoda, N Cremades, D Klenerman, CM Dobson, NW Wood, EV Pavlov, S Gandhi, AY Abramov
Development (Cambridge, England)
(2016)
143
(doi: 10.1242/dev.139345)
Amyloid fibrils as building blocks for natural and artificial functional materials
TPJ Knowles, R Mezzenga
Advanced materials (Deerfield Beach, Fla.)
(2016)
28
(doi: 10.1002/adma.201505961)
A Microfluidic Platform for Real-Time Detection and Quantification of Protein-Ligand Interactions.
TW Herling, DJ O'Connell, MC Bauer, J Persson, U Weininger, TPJ Knowles, S Linse
Biophys J
(2016)
110
(doi: 10.1016/j.bpj.2016.03.038)
Self-assembly of MPG1, a hydrophobin protein from the rice blast fungus that forms functional amyloid coatings, occurs by a surface-driven mechanism
CLL Pham, A Rey, V Lo, M Soulès, Q Ren, G Meisl, TPJ Knowles, AH Kwan, M Sunde
Sci Rep
(2016)
6
(doi: 10.1038/srep25288)
PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits.
MJ Broadhead, MH Horrocks, F Zhu, L Muresan, R Benavides-Piccione, J DeFelipe, D Fricker, MV Kopanitsa, RR Duncan, D Klenerman, NH Komiyama, SF Lee, SGN Grant
Scientific reports
(2016)
6
(doi: 10.1038/srep24626)
Electrostatically-guided inhibition of Curli amyloid nucleation by the CsgC-like family of chaperones
JD Taylor, WJ Hawthorne, J Lo, A Dear, N Jain, G Meisl, M Andreasen, C Fletcher, M Koch, N Darvill, N Scull, A Escalera-Maurer, L Sefer, R Wenman, S Lambert, J Jean, Y Xu, B Turner, SG Kazarian, MR Chapman, D Bubeck, A de Simone, TPJ Knowles, SJ Matthews
Scientific Reports
(2016)
6
(doi: 10.1038/srep24656)
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
V Kakkar, C Månsson, EP de Mattos, S Bergink, M van der Zwaag, MAWH van Waarde, NJ Kloosterhuis, R Melki, RTP van Cruchten, S Al-Karadaghi, P Arosio, CM Dobson, TPJ Knowles, GP Bates, JM van Deursen, S Linse, B van de Sluis, C Emanuelsson, HH Kampinga
Molecular Cell
(2016)
62
(doi: 10.1016/j.molcel.2016.03.017)
A general reaction network unifies the aggregation behaviour of the A$\beta$42 peptide and its variants
G Meisl, X Yang, CM Dobson, S Linse, TPJ Knowles
(2016)
(doi: 10.48550/arxiv.1604.00828)
Yusuf Hamied Department of Chemistry
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