Centre for Experimental Biophysical Chemistry

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  • Currently displaying 761 - 780 of 1217 publications
Author(s)
Publication title
Journal Name
Publication year
The stoichiometric ‘signature’ of Rhodopsin-family G protein-coupled receptors
JH Felce, SL Latty, RG Knox, SR Mattick, Y Lui, SF Lee, D Klenerman, SJ Davis
(2017)
(doi: 10.1101/112466)
Acceleration of α-synuclein aggregation.
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis
(2017)
24
(doi: 10.1080/13506129.2017.1292904)
A cell-topography based mechanism for ligand discrimination by the T-cell receptor
RA Fernandes, KA Ganzinger, J Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
(2017)
(doi: 10.1101/109785)
A natural product inhibits the initiation of α-synuclein aggregation & suppresses its toxicity
M Perni, C Galvagnion, A Maltsev, G Meisl, MBD Müller, PK Challa, JB Kirkegaard, P Flagmeier, SIA Cohen, R Cascella, SW Chen, R Limboker, P Sormanni, GT Heller, FA Aprile, N Cremades, C Cecchi, F Chiti, EAA Nollen, TPJ Knowles, M Vendruscolo, A Bax, M Zasloff, CM Dobson
Proceedings of the National Academy of Sciences
(2017)
114
(doi: 10.1073/pnas.1610586114)
Attenuating the Toxicity of Amyloid-Beta Aggregation with Specific Species
R Limbocker, B Mannini, M Perni, S Chia, G Heller, FS Ruggeri, J Habchi, G Meisl, PK Challa, M Zasloff, TPJ Knowles, M Vendruscolo, CM Dobson
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2673)
Direct Modulation of the Mitochondrial Permeability Transition Pore by Oligomeric Alpha-Synuclein Causes Toxicity in PD
M Ludtmann, P Angelova, M-L Choi, M Horrocks, A Baev, D Little, M Devine, P Gissen, E Pavlov, D Klenerman, A Abramov, S Gandhi
Biophysical Journal
(2017)
112
(doi: 10.1016/j.bpj.2016.11.2351)
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
On-chip label-free protein analysis with downstream electrodes for direct removal of electrolysis products
KL Saar, Y Zhang, T Müller, CP Kumar, S Devenish, A Lynn, U Łapińska, X Yang, S Linse, TPJ Knowles
Lab on a chip
(2017)
18
(doi: 10.1039/c7lc00797c)
Imaging the early events of T-cell triggering
D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single α-synuclein oligomers are hydrophobically distinct from mature fibrils
J-E Lee, MN Bongiovanni, M Rodrigues, CM Dobson, SF Lee, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Ultrasensitive measurement of Ca2+ influx into lipid vesicles induced by protein aggregates
P Flagmeier, S De, DC Wirthensohn, SF Lee, C Vincke, S Muyldermans, TP Knowles, S Gandhi, CM Dobson, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Evidence for self-replication of Alzheimer-associated Aβ42 amyloid along the sides of fibrils
M Tornquist, R Cukalevski, U Weininger, G Meisl, TPJ Knowles, T Leiding, M Akke, S Linse
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Kinetics of protein aggregation
T Knowles
FEBS JOURNAL
(2017)
284
Microfluidic devices fabricated using fast wafer-scale LED-lithography patterning
PK Challa, T Kartanas, J Charmet, TPJ Knowles
Biomicrofluidics
(2017)
11
(doi: 10.1063/1.4976690)
Non-perturbative single-molecule imaging of tau aggregates by genetic code expansion
F Kundel, MH Horrocks, Y Ye, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Size dependent structure and effects of amyloid beta42
D Wirthensohn, F Kundel, S De, C Hughes, MH Horrocks, P Flagmeier, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Single amyloid aggregates chemical and structural analysis by infrared nanospectroscopy
FS Ruggeri, J Habchi, C Sean, M Vendruscolo, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Mechanisms of Amyloid-β 42 oligomer formation from kinetic analysis
TC Michaels, A Saric, HW Lazell, P Arosio, M Vendruscolo, CM Dobson, S Linse, TPJ Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
DNA PAINTing amyloid aggregates
MH Horrocks, D Whiten, Y Zuo, L Calo, MG Spillantini, S Gandhi, D Klenerman
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2017)
46
Secondary nucleation of monomers on fibril surface dominates $\alpha$-synuclein aggregation and provides autocatalytic amyloid amplification
R Gaspar, G Meisl, AK Buell, L Young, CF Kaminski, TPJ Knowles, E Sparr, S Linse
Q Rev Biophys
(2017)
50
(doi: 10.1017/s0033583516000172)
Yusuf Hamied Department of Chemistry
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