Centre for Experimental Biophysical Chemistry

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  • Currently displaying 681 - 700 of 1216 publications
Author(s)
Publication title
Journal Name
Publication year
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH.
IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chemical science
(2018)
9
(doi: 10.1039/c8sc01109e)
Stochastic calculus of protein filament formation under spatial confinement
TCT Michaels, AJ Dear, TPJ Knowles
New Journal of Physics
(2018)
20
(doi: 10.1088/1367-2630/aac0bc)
Rapid Growth of Acetylated Aβ(16–20) into Macroscopic Crystals
C Bortolini, LH Klausen, SV Hoffmann, NC Jones, D Saadeh, Z Wang, TPJ Knowles, M Dong
ACS nano
(2018)
12
(doi: 10.1021/acsnano.8b00448)
Single-Molecule Light-Sheet Imaging of Suspended T Cells
A Ponjavic, J McColl, AR Carr, AM Santos, K Kulenkampff, A Lippert, SJ Davis, D Klenerman, SF Lee
Biophys J
(2018)
114
(doi: 10.1016/j.bpj.2018.02.044)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, FS Ruggeri, M Sanguanini, I Idini, JR Kumita, E Sparr, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Nat Chem
(2018)
10
(doi: 10.1038/s41557-018-0031-x)
Alpha-synuclein induces ferroptosis through generation of lipid peroxidation and calcium deregulation
PR Angelova, M-L Choi, MH Horrocks, D Klenerman, S Gandhi, AY Abramov
Free Radical Biology and Medicine
(2018)
120
(doi: 10.1016/j.freeradbiomed.2018.04.137)
Weighing one protein with light
SF Lee, D Klenerman
Science
(2018)
360
(doi: 10.1126/science.aat5851)
Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell
D Lando, S Basu, TJ Stevens, A Riddell, KJ Wohlfahrt, Y Cao, W Boucher, M Leeb, LP Atkinson, SF Lee, B Hendrich, D Klenerman, ED Laue
Nature protocols
(2018)
13
(doi: 10.1038/nprot.2018.017)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
Cell
(2018)
173
(doi: 10.1016/j.cell.2018.03.056)
Anharmonic acoustic effects during DNA hybridization on an electrochemical quartz crystal resonator
S Swarbrick, I Efimov, VP Ostanin, D Klenerman, A Stolzing, SK Ghosh
Electrochimica Acta
(2018)
269
(doi: 10.1016/j.electacta.2018.03.014)
Water-Dispersible Polydopamine-Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion.
S Sieste, T Mack, CV Synatschke, C Schilling, C Meyer Zu Reckendorf, L Pendi, S Harvey, FS Ruggeri, TPJ Knowles, C Meier, DYW Ng, T Weil, B Knöll
Advanced Healthcare Materials
(2018)
7
(doi: 10.1002/adhm.201701485)
Biophotonics of Native Silk Fibrils.
U Shimanovich, D Pinotsi, K Shimanovich, N Yu, S Bolisetty, J Adamcik, R Mezzenga, J Charmet, F Vollrath, E Gazit, CM Dobson, GK Schierle, C Holland, CF Kaminski, TPJ Knowles
Macromol Biosci
(2018)
18
(doi: 10.1002/mabi.201700295)
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species (vol 5, 171399, 2018)
L-M Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, M Rodrigues, CM Dobson, S Gandhi, SE Bohndiek, TN Snaddon, SF Lee
Royal Society Open Science
(2018)
5
(doi: 10.1098/rsos.180308)
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading.
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, N Esteras, AY Abramov, TJP Knowles, M Goedert, D Klenerman
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00094)
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide
SIA Cohen, R Cukalevski, TCT Michaels, A Šarić, M Törnquist, M Vendruscolo, CM Dobson, AK Buell, TPJ Knowles, S Linse
Nature Chemistry
(2018)
10
(doi: 10.1038/s41557-018-0023-x)
Optical Structural Analysis of Individual α‐Synuclein Oligomers
JA Varela, M Rodrigues, S De, P Flagmeier, S Gandhi, CM Dobson, D Klenerman, SF Lee
Angewandte Chemie
(2018)
130
(doi: 10.1002/ange.201710779)
The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity.
D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, D Klenerman, AM van Oijen, H Ecroyd
The Journal of biological chemistry
(2018)
293
(doi: 10.1074/jbc.M117.813865)
Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity.
F Kundel, S De, P Flagmeier, MH Horrocks, M Kjaergaard, SL Shammas, SE Jackson, CM Dobson, D Klenerman
ACS Chem Biol
(2018)
13
(doi: 10.1021/acschembio.7b01039)
Reaction rate theory for supramolecular kinetics: application to protein aggregation
TCT Michaels, LX Liu, S Curk, PG Bolhuis, A Saric, TPJ Knowles
(2018)
(doi: 10.48550/arxiv.1803.04851)
Shedding light on aberrant interactions – a review of modern tools for studying protein aggregates
F Kundel, L Tosatto, DR Whiten, DC Wirthensohn, MH Horrocks, D Klenerman
The FEBS Journal
(2018)
285
(doi: 10.1111/febs.14409)
Yusuf Hamied Department of Chemistry
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