Centre for Experimental Biophysical Chemistry

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  • Currently displaying 541 - 560 of 1145 publications
Author(s)
Publication title
Journal Name
Publication year
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
General sol to gel transition of liquid-liqud phase separated protein under shear
Y Shen, S Qamar, D Vigolo, A Kamada, S Zhang, P St George-Hyslop, T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2019)
48
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, CM Dobson, M Vendruscolo
ACS chemical neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00141)
Oligomer Diversity during the Aggregation of the Repeat Region of Tau.
M Kjaergaard, AJ Dear, F Kundel, S Qamar, G Meisl, TPJ Knowles, D Klenerman
ACS Chemical Neuroscience
(2018)
9
(doi: 10.1021/acschemneuro.8b00250)
Resolving protein mixtures using microfluidic diffusional sizing combined with synchrotron radiation circular dichroism
C Bortolini, T Kartanas, D Copic, I Condado Morales, Y Zhang, PK Challa, Q Peter, T Jávorfi, R Hussain, M Dong, G Siligardi, TPJ Knowles, J Charmet
Lab on a Chip
(2018)
19
(doi: 10.1039/c8lc00757h)
Mapping Surface Hydrophobicity of α‑Synuclein Oligomers at the Nanoscale
J-E Lee, JC Sang, M Rodrigues, AR Carr, MH Horrocks, S De, MN Bongiovanni, P Flagmeier, CM Dobson, DJ Wales, SF Lee, D Klenerman
Nano Letters
(2018)
18
(doi: 10.1021/acs.nanolett.8b02916)
Image-Assisted Microvessel-on-a-Chip Platform for Studying Cancer Cell Transendothelial Migration Dynamics
C Bertulli, M Gerigk, N Piano, Y Liu, D Zhang, T Müller, TJ Knowles, YYS Huang
Scientific reports
(2018)
8
(doi: 10.1038/s41598-018-30776-0)
Mechanobiology of Protein Droplets: Force Arises from Disorder.
TJ Welsh, Y Shen, A Levin, TPJ Knowles
Cell
(2018)
175
(doi: 10.1016/j.cell.2018.11.020)
Quantifying Co-Oligomer Formation by α-Synuclein
M Iljina, AJ Dear, GA Garcia, S De, L Tosatto, P Flagmeier, DR Whiten, TCT Michaels, D Frenkel, CM Dobson, TPJ Knowles, D Klenerman
ACS Nano
(2018)
12
(doi: 10.1021/acsnano.8b03575)
Filamentous aggregates are fragmented by the proteasome holoenzyme
R Cliffe, JC Sang, F Kundel, D Finley, D Klenerman, Y Ye
Cell Reports
(2018)
(doi: 10.1101/467068)
Sensitive light-sheet microscopy in multiwell plates using an AFM cantilever.
A Ponjavic, Y Ye, E Laue, SF Lee, D Klenerman
Biomed Opt Express
(2018)
9
(doi: 10.1364/boe.9.005863)
Characterisation of particle-surface interactions via anharmonic acoustic transduction
C da Silva Granja, N Sandström, I Efimov, VP Ostanin, W van der Wijngaart, D Klenerman, SK Ghosh
Sensors and Actuators B Chemical
(2018)
272
(doi: 10.1016/j.snb.2018.05.016)
Automated Behavioral Analysis of Large C. elegans Populations Using a Wide Field-of-view Tracking Platform.
M Perni, S Casford, FA Aprile, EA Nollen, TPJ Knowles, M Vendruscolo, CM Dobson
Journal of visualized experiments : JoVE
(2018)
2018
(doi: 10.3791/58643)
Statistical Mechanics of Globular Oligomer Formation by Protein Molecules.
AJ Dear, A Šarić, TCT Michaels, CM Dobson, TPJ Knowles
The Journal of Physical Chemistry B
(2018)
122
(doi: 10.1021/acs.jpcb.8b07805)
Correction to: Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson’s disease pathogenesis
CD Hughes, ML Choi, M Ryten, L Hopkins, A Drews, JA Botía, M Iljina, M Rodrigues, SA Gagliano, S Gandhi, C Bryant, D Klenerman
Acta neuropathologica
(2018)
137
(doi: 10.1007/s00401-018-1919-7)
Direct observation of murine prion protein replication in vitro
JC Sang, G Meisl, AM Thackray, L Hong, A Ponjavic, TPJ Knowles, R Bujdoso, D Klenerman
Journal of the American Chemical Society
(2018)
140
(doi: 10.1021/jacs.8b08311)
Nanoscopic characterization of individual endogenous protein aggregates in human neuronal cells
DR Whiten, Y Zuo, L Calo, M-L Choi, S De, P Flagmeier, DC Wirthensohn, F Kundel, RT Ranasinghe, SE Sanchez, D Athauda, SF Lee, CM Dobson, S Gandhi, M-G Spillantini, D Klenerman, MH Horrocks
ChemBioChem
(2018)
19
(doi: 10.1002/cbic.201800209)
SAR by kinetics for drug discovery in protein misfolding diseases
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Proceedings of the National Academy of Sciences of the United States of America
(2018)
115
(doi: 10.1073/pnas.1807884115)
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, CM Dobson, M Vendruscolo, TPJ Knowles
Nature communications
(2018)
9
(doi: 10.1038/s41467-018-06345-4)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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