Centre for Experimental Biophysical Chemistry

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  • Currently displaying 541 - 560 of 1111 publications
Author(s)
Publication title
Journal Name
Publication year
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease.
MHR Ludtmann, PR Angelova, MH Horrocks, ML Choi, M Rodrigues, AY Baev, AV Berezhnov, Z Yao, D Little, B Banushi, AS Al-Menhali, RT Ranasinghe, DR Whiten, R Yapom, KS Dolt, MJ Devine, P Gissen, T Kunath, M Jaganjac, EV Pavlov, D Klenerman, AY Abramov, S Gandhi
Nat Commun
(2018)
9
(doi: 10.1038/s41467-018-04422-2)
On the role of sidechain size and charge in the aggregation of A
X Yang, G Meisl, B Frohm, E Thulin, TPJ Knowles, S Linse
Proc Natl Acad Sci U S A
(2018)
115
(doi: 10.1073/pnas.1803539115)
Kinetic analysis of amyloid formation
G Meisl, TCT Michaels, S Linse, TPJ Knowles
Methods in Molecular Biology
(2018)
1779
(doi: 10.1007/978-1-4939-7816-8_12)
Cooperative Assembly of Hsp70 Subdomain Clusters.
MA Wright, FA Aprile, MMJ Bellaiche, TCT Michaels, T Müller, P Arosio, M Vendruscolo, CM Dobson, TPJ Knowles
Biochemistry
(2018)
57
(doi: 10.1021/acs.biochem.8b00151)
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
Y Song, TCT Michaels, Q Ma, Z Liu, H Yuan, S Takayama, TPJ Knowles, HC Shum
Nature Communications
(2018)
9
(doi: 10.1038/s41467-018-04510-3)
C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH
IM van der Wateren, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion
Chem Sci
(2018)
9
(doi: 10.1039/c8sc01109e)
Reaction rate theory for supramolecular kinetics: application to protein aggregation
TCT Michaels, LX Liu, S Curk, PG Bolhuis, A Šarić, TPJ Knowles
Molecular Physics
(2018)
116
(doi: 10.1080/00268976.2018.1474280)
Rapid Growth of Acetylated Aβ(16-20) into Macroscopic Crystals.
C Bortolini, LH Klausen, SV Hoffmann, NC Jones, D Saadeh, Z Wang, TPJ Knowles, M Dong
ACS nano
(2018)
12
(doi: 10.1021/acsnano.8b00448)
Stochastic calculus of protein filament formation under spatial confinement
TCT Michaels, AJ Dear, TPJ Knowles
New Journal of Physics
(2018)
20
(doi: 10.1088/1367-2630/aac0bc)
Single-Molecule Light-Sheet Imaging of Suspended T Cells.
A Ponjavic, J McColl, AR Carr, AM Santos, K Kulenkampff, A Lippert, SJ Davis, D Klenerman, SF Lee
Biophysical Journal
(2018)
114
(doi: 10.1016/j.bpj.2018.02.044)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes.
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, FS Ruggeri, M Sanguanini, I Idini, JR Kumita, E Sparr, S Linse, CM Dobson, TPJ Knowles, M Vendruscolo
Nat Chem
(2018)
10
(doi: 10.1038/s41557-018-0031-x)
Alpha-synuclein induces ferroptosis through generation of lipid peroxidation and calcium deregulation
PR Angelova, M-L Choi, MH Horrocks, D Klenerman, S Gandhi, AY Abramov
Free Radical Biology and Medicine
(2018)
120
(doi: 10.1016/j.freeradbiomed.2018.04.137)
Weighing one protein with light
SF Lee, D Klenerman
Science
(2018)
360
(doi: 10.1126/science.aat5851)
Phase Separation of FUS is Modulated by Methylation State of Cation-π Interactions and Interaction with TNPO1
PH St George-Hyslop, S Qamar, G Wang, SJ Randle, FS Ruggeri, J Varela, CF Kaminski, GS Kaminski, M Vendruscolo, TPJ Knowles, D Klenerman, CE Holt, Q Lin, W meadows
Cell
(2018)
(doi: 10.1016/j.cell.2018.03.056)
Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.
D Lando, S Basu, TJ Stevens, A Riddell, KJ Wohlfahrt, Y Cao, W Boucher, M Leeb, LP Atkinson, SF Lee, B Hendrich, D Klenerman, ED Laue
Nat Protoc
(2018)
13
(doi: 10.1038/nprot.2018.017)
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions.
S Qamar, G Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, EC Phillips, A Miyashita, D Williams, F Ströhl, W Meadows, R Ferry, VJ Dardov, GG Tartaglia, LA Farrer, GS Kaminski Schierle, CF Kaminski, CE Holt, PE Fraser, G Schmitt-Ulms, D Klenerman, T Knowles, M Vendruscolo, P St George-Hyslop
Cell
(2018)
173
(doi: 10.1016/j.cell.2018.03.056)
Anharmonic acoustic effects during DNA hybridization on an electrochemical quartz crystal resonator
S Swarbrick, I Efimov, VP Ostanin, D Klenerman, A Stolzing, SK Ghosh
Electrochimica Acta
(2018)
269
(doi: 10.1016/j.electacta.2018.03.014)
Water-Dispersible Polydopamine-Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion
S Sieste, T Mack, CV Synatschke, C Schilling, C Meyer Zu Reckendorf, L Pendi, S Harvey, FS Ruggeri, TPJ Knowles, C Meier, DYW Ng, T Weil, B Knöll
Adv Healthc Mater
(2018)
7
(doi: 10.1002/adhm.201701485)
Measurement of Tau Filament Fragmentation Provides Insights into Prion-like Spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, N Esteras, AY Abramov, TJP Knowles, M Goedert, D Klenerman
ACS Chem Neurosci
(2018)
9
(doi: 10.1021/acschemneuro.8b00094)
Biophotonics of Native Silk Fibrils.
U Shimanovich, D Pinotsi, K Shimanovich, N Yu, S Bolisetty, J Adamcik, R Mezzenga, J Charmet, F Vollrath, E Gazit, CM Dobson, GK Schierle, C Holland, CF Kaminski, TPJ Knowles
Macromol Biosci
(2018)
18
(doi: 10.1002/mabi.201700295)
Yusuf Hamied Department of Chemistry
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