Centre for Experimental Biophysical Chemistry

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  • Currently displaying 461 - 480 of 1111 publications
Author(s)
Publication title
Journal Name
Publication year
Autocatalytic amplification of Alzheimer-associated Aβ42 peptide aggregation in human cerebrospinal fluid.
R Frankel, M Törnquist, G Meisl, O Hansson, U Andreasson, H Zetterberg, K Blennow, B Frohm, T Cedervall, TPJ Knowles, T Leiding, S Linse
Communications biology
(2019)
2
(doi: 10.1038/s42003-019-0612-2)
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether.
Y-C Liao, M Fernandopulle, G Wang, H Choi, L Hao, CM Drerup, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, M Nelson, M Czekalska, G Musteikyte, R Patel, C Stephens, A Pasolli, L Forrest, PS George-Hyslop, J Lippincott-Schwartz, ME Ward
Cell
(2019)
179
(doi: 10.1016/j.cell.2019.08.050)
Characterizing Individual Protein Aggregates by Infrared Nanospectroscopy and Atomic Force Microscopy.
FS Ruggeri, T Šneideris, S Chia, M Vendruscolo, TPJ Knowles
Journal of Visualized Experiments
(2019)
2019
(doi: 10.3791/60108)
N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of Their Oligomers by the Proteasome Holoenzyme
Y Ye, D Klenerman, D Finley
Journal of Molecular Biology
(2019)
432
(doi: 10.1016/j.jmb.2019.08.021)
Scalable integration of nano-, and microfluidics with hybrid two-photon lithography.
O Vanderpoorten, Q Peter, PK Challa, UF Keyser, J Baumberg, CF Kaminski, TPJ Knowles
Microsystems and Nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0080-3)
Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification
PR Lindstedt, FA Aprile, MJ Matos, M Perni, JB Bertoldo, B Bernardim, Q Peter, G Jiménez-Osés, TPJ Knowles, CM Dobson, F Corzana, M Vendruscolo, GJL Bernardes
ACS Central Science
(2019)
5
(doi: 10.1021/acscentsci.9b00467)
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
G Heller, F Aprile, T Michaels, R Limbocker, M Perni, FS Ruggeri, B Mannini, T Löhr, M Bonomi, C Camilloni, A De Simone, I Felli, R Pierattelli, T Knowles, C Dobson, M Vendruscolo
(2019)
(doi: 10.1101/729392)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S De, DR Whiten, FS Ruggeri, C Hughes, M Rodrigues, DI Sideris, CG Taylor, FA Aprile, S Muyldermans, TPJ Knowles, M Vendruscolo, C Bryant, K Blennow, I Skoog, S Kern, H Zetterberg, D Klenerman
Acta Neuropathol Commun
(2019)
7
(doi: 10.1186/s40478-019-0777-4)
ThX: a next generation probe for the early detection of amyloid aggregates
L-M Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, D Klenerman, CM Dobson, CA Hunter, SE Bohndiek, TN Snaddon, SF Lee
BIOPHYSICAL JOURNAL
(2019)
121
(doi: 10.1101/713594)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
K Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, T Knowles, SILVIA HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017.v1)
Clathrin-Inspired Coating and Stabilization of Liposomes by DNA Self-Assembly
KN Baumann, L Piantanida, J García-Nafría, D Sobota, K Voïtchovsky, TPJ Knowles, S HERNANDEZ AINSA
(2019)
(doi: 10.26434/chemrxiv.8859017)
Rapid two-dimensional characterisation of proteins insolution
KL Saar, Q Peter, T Müller, PK Challa, TW Herling, TPJ Knowles
Microsystems & Nanoengineering
(2019)
5
(doi: 10.1038/s41378-019-0072-3)
Universality of filamentous aggregation phenomena.
TCT Michaels, AJ Dear, TPJ Knowles
Physical review. E
(2019)
99
(doi: 10.1103/physreve.99.062415)
A cell topography-based mechanism for ligand discrimination by the T cell receptor.
RA Fernandes, KA Ganzinger, JC Tzou, P Jönsson, SF Lee, M Palayret, AM Santos, AR Carr, A Ponjavic, VT Chang, C Macleod, BC Lagerholm, AE Lindsay, O Dushek, A Tilevik, SJ Davis, D Klenerman
Proc Natl Acad Sci U S A
(2019)
116
(doi: 10.1073/pnas.1817255116)
Analysis of αB-crystallin polydispersity in solution through native microfluidic electrophoresis.
MA Wright, FS Ruggeri, KL Saar, PK Challa, JLP Benesch, TPJ Knowles
Analyst
(2019)
144
(doi: 10.1039/c9an00382g)
Programmable On-Chip Artificial Cell Producing Post-Translationally Modified Ubiquitinated Protein
S Zilberzwige-Tal, A Levin, Z Toprakcioglu, TPJ Knowles, E Gazit, J Elbaz
Small
(2019)
15
(doi: 10.1002/smll.201901780)
Poly(ADP-ribose) links the DNA damage response to biomineralization
K Mueller
Cell Rep
(2019)
27
(doi: 10.1016/j.celrep.2019.05.038)
A general in vitro assay to study enzymatic activities of the ubiquitin system
Y Zuo, BK Chong, K Jiang, D Finley, D Klenerman, Y Ye
(2019)
(doi: 10.1101/660894)
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation
MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, B Bernardim, KL Saar, I Compañón, F Corzana, TPJ Knowles, G Jiménez-Osés, GJL Bernardes
Angewandte Chemie International Edition
(2019)
58
(doi: 10.1002/anie.201901405)
Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-b aggregates
T Scheidt, U Łapińska, JR Kumita, DR Whiten, D Klenerman, MR Wilson, SIA Cohen, S Linse, M Vendruscolo, CM Dobson, TPJ Knowles, P Arosio
Sci Adv
(2019)
5
(doi: 10.1126/sciadv.aau3112)
Yusuf Hamied Department of Chemistry
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