Centre for Experimental Biophysical Chemistry

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  • Currently displaying 281 - 300 of 1111 publications
Author(s)
Publication title
Journal Name
Publication year
Trapping or slowing the diffusion of T cell receptors at close contacts initiates T cell signaling
KY Chen, E Jenkins, M Körbel, A Ponjavic, AH Lippert, AM Santos, N Ashman, C O'Brien-Ball, J McBride, D Klenerman, SJ Davis
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2024250118)
Deformable and Robust Core-Shell Protein Microcapsules Templated by Liquid-Liquid Phase-Separated Microdroplets
Y Xu, Y Shen, TCT Michaels, KN Baumann, D Vigolo, Q Peter, Y Lu, KL Saar, D Vella, H Zhu, B Li, H Yang, APM Guttenplan, M Rodriguez-Garcia, D Klenerman, TPJ Knowles
Advanced Materials Interfaces
(2021)
8
(doi: 10.1002/admi.202101071)
The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces
T Scheidt, JA Carozza, CC Kolbe, FA Aprile, O Tkachenko, MMJ Bellaiche, G Meisl, QAE Peter, TW Herling, S Ness, M Castellana-Cruz, JLP Benesch, M Vendruscolo, CM Dobson, P Arosio, TPJ Knowles
Proc Natl Acad Sci U S A
(2021)
118
(doi: 10.1073/pnas.2108790118|1of8)
New Frontiers for Machine Learning in Protein Science
AS Morgunov, KL Saar, M Vendruscolo, TPJ Knowles
Journal of Molecular Biology
(2021)
433
(doi: 10.1016/j.jmb.2021.167232)
Alpha synuclein only forms fibrils in vitro when larger than its critical size of 70 monomers.
SE Sanchez, DR Whiten, G Meisl, FS Ruggeri, E Hidari, D Klenerman
Chembiochem : a European journal of chemical biology
(2021)
22
(doi: 10.1002/cbic.202100285)
Unraveling the Physicochemical Determinants of Protein Liquid-liquid Phase Separation by Nanoscale Infrared Vibrational Spectroscopy
FS Ruggeri, AM Miller, M Vendruscolo, TPJ Knowles
Bio Protoc
(2021)
11
(doi: 10.21769/BioProtoc.4122)
Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease
E Lobanova, D Whiten, FS Ruggeri, CG Taylor, A Kouli, Z Xia, D Emin, YP Zhang, JYL Lam, CH Williams-Gray, D Klenerman
Brain : a journal of neurology
(2021)
145
(doi: 10.1093/brain/awab306)
Liquid–Liquid Phase‐Separated Systems from Reversible Gel–Sol Transition of Protein Microgels (Adv. Mater. 33/2021)
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Advanced Materials
(2021)
33
(doi: 10.1002/adma.202170258)
Conformational Expansion of Tau in Condensates Promotes Irreversible Aggregation
J Wen, L Hong, G Krainer, Q-Q Yao, TPJ Knowles, S Wu, S Perrett
Journal of the American Chemical Society
(2021)
143
(doi: 10.1021/jacs.1c03078)
Feedback control of protein aggregation.
AJ Dear, TCT Michaels, TPJ Knowles, L Mahadevan
The Journal of Chemical Physics
(2021)
155
(doi: 10.1063/5.0055925)
Quantum Emitter Localization in Layer-Engineered Hexagonal Boron Nitride.
JC Stewart, Y Fan, JSH Danial, A Goetz, AS Prasad, OJ Burton, JA Alexander-Webber, SF Lee, SM Skoff, V Babenko, S Hofmann
ACS nano
(2021)
15
(doi: 10.1021/acsnano.1c04467)
Noncontact Nanoscale Imaging of Cells.
D Klenerman, Y Korchev, P Novak, A Shevchuk
Annu Rev Anal Chem (Palo Alto Calif)
(2021)
14
(doi: 10.1146/annurev-anchem-091420-120101)
Mutations in two SARS-CoV-2 variants of concern reflect two distinct strategies of antibody escape
S Fiedler, V Denninger, A Morgunov, A Ilsley, R Worth, G Meisl, C Xu, M Piziorska, F Ricci, A Malik, S Devenish, M Schneider, V Kosmoliaptsis, A Aguzzi, A Iwasaki, H Fiegler, T Knowles
(2021)
(doi: 10.1101/2021.07.23.453327)
LAG3 is not expressed in human and murine neurons and does not modulate α‐synucleinopathies
M Emmenegger, E De Cecco, M Hruska-Plochan, T Eninger, MM Schneider, M Barth, E Tantardini, P de Rossi, M Bacioglu, RG Langston, A Kaganovich, N Bengoa-Vergniory, A Gonzalez-Guerra, M Avar, D Heinzer, R Reimann, LM Häsler, TW Herling, NS Matharu, N Landeck, K Luk, R Melki, PJ Kahle, S Hornemann, TPJ Knowles, MR Cookson, M Polymenidou, M Jucker, A Aguzzi
EMBO molecular medicine
(2021)
13
(doi: 10.15252/emmm.202114745)
Understanding the role of memory re-activation and cross-reactivity in the defense against SARS-CoV-2
V Denninger, C Xu, G Meisl, A Morgunov, S Fiedler, A Ilsley, M Emmenegger, A Malik, M Piziorska, M Schneider, S Devenish, V Kosmoliaptsis, A Aguzzi, H Fiegler, T Knowles
(2021)
(doi: 10.1101/2021.07.23.453352)
Liquid-liquid phase separated systems from reversible gel-sol transition of protein microgels
Y Xu, R Qi, H Zhu, B Li, Y Shen, G Krainer, D Klenerman, TPJ Knowles
Adv Mater
(2021)
33
(doi: 10.1002/adma.202008670)
The unhappy chaperone.
S Linse, K Thalberg, TPJ Knowles
QRB Discovery
(2021)
2
(doi: 10.1017/qrd.2021.5)
Protein Conjugation by Electrophilic Alkynylation using 5-(Alkynyl) dibenzothiophenium Triflates
V Laserna, A Istrate, K Kafuta, TA Hakala, TPJ Knowles, M Alcarazo, GJL Bernardes
Bioconjugate Chemistry
(2021)
32
(doi: 10.1021/acs.bioconjchem.1c00317)
Biomembranes in Bioelectronic Sensing
AK Jayaram, AM Pappa, S Ghosh, ZA Manzer, WC Traberg, TPJ Knowles, S Daniel, RM Owens
Trends in biotechnology
(2021)
40
(doi: 10.1016/j.tibtech.2021.06.001)
Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
DI Sideris, JSH Danial, D Emin, FS Ruggeri, Z Xia, YP Zhang, E Lobanova, H Dakin, S De, A Miller, JC Sang, TPJ Knowles, M Vendruscolo, G Fraser, D Crowther, D Klenerman
Brain Communications
(2021)
3
(doi: 10.1093/braincomms/fcab147)
Yusuf Hamied Department of Chemistry
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