Centre for Experimental Biophysical Chemistry

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  • Currently displaying 281 - 300 of 1216 publications
Author(s)
Publication title
Journal Name
Publication year
Non-specificity fingerprints for clinical stage antibodies in solution
TW Herling, G Invernizzi, H Ausserwöger, JR Bjelke, T Egebjerg, S Lund, N Lorenzen, TPJ Knowles
(2023)
(doi: 10.1101/2023.02.13.528263)
Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling.
M Emmenegger, R Worth, S Fiedler, SRA Devenish, TPJ Knowles, A Aguzzi
STAR Protoc
(2023)
4
(doi: 10.1016/j.xpro.2023.102095)
Characterizing protein interactions in biomolecular phase separation
H Ausserwöger, G Krainer, D Qian, T Welsh, T Sneideris, MM Schneider, G Invernizzi, TW Herling, N Lorenzen, TP Knowles
Biophysical journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.963)
Approximate analytical solution to the Flory-Huggins model
D Qian, TCT Michaels, TPJ Knowles
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.1243)
Multiphase condensates from a kinetically arrested phase transition
N Erkamp, T Sneideris, H Ausserwöger, D Qian, S Qamar, J Nixon-Abell, PS George-Hyslop, J Schmit, D Weitz, TPJ Knowles
Nature Communications
(2023)
14
(doi: 10.1038/s41467-023-36059-1)
POLCAM: Instant molecular orientation microscopy for the life sciences
E Bruggeman, O Zhang, L-M Needham, M Körbel, S Daly, M Cheetham, R Peters, T Wu, AS Klymchenko, SJ Davis, EK Paluch, D Klenerman, MD Lew, K O’Holleran, SF Lee
(2023)
(doi: 10.1101/2023.02.07.527479)
Direct digital sensing of protein biomarkers in solution
G Krainer, KL Saar, WE Arter, TJ Welsh, MA Czekalska, RPB Jacquat, Q Peter, WC Traberg, A Pujari, AK Jayaram, P Challa, CG Taylor, L-M van der Linden, T Franzmann, RM Owens, S Alberti, D Klenerman, TPJ Knowles
Nature communications
(2023)
14
(doi: 10.1038/s41467-023-35792-x)
Designer proteins as potential therapeutic biomolecular condensates
TLC Ng, M Hoare, T Welsh, S Tomas, E Wilde, TPJ Knowles, LS Itzhaki, JR Kumita
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.568)
Bioprinting microporous functional living materials from protein-based core-shell microgels
Y Ou, S Cao, Y Zhang, H Zhu, C Guo, W Yan, F Xin, W Dong, Y Zhang, M Narita, Z Yu, T Knowles
Nature communications
(2023)
14
(doi: 10.1038/s41467-022-35140-5)
Adsorption of RNA to interfaces of biomolecular condensates enables wetting transitions
NA Erkamp, M Farag, D Qian, T Sneideris, TJ Welsh, H Ausserwöger, DA Weitz, RV Pappu, TPJ Knowles
(2023)
(doi: 10.1101/2023.01.12.523837)
Enhanced surface nanoanalytics of transient biomolecular processes
AM Miller, S Chia, Z Toprakcioglo, T Hakala, R Schmid, Y Feng, T Kartanas, A Kamada, M Vendruscolo, FS Ruggeri, T Knowles
Sci Adv
(2023)
9
(doi: 10.1126/sciadv.abq3151)
Design of amyloidogenic peptide traps
DD Sahtoe, EA Andrzejewska, HL Han, E Rennella, MM Schneider, G Meisl, M Ahlrichs, J Decarreau, H Nguyen, A Kang, P Levine, M Lamb, X Li, AK Bera, LE Kay, TPJ Knowles, D Baker
(2023)
(doi: 10.1101/2023.01.13.523785)
Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
M Emmenegger, E De Cecco, D Lamparter, RPB Jacquat, J Riou, D Menges, T Ballouz, D Ebner, MM Schneider, IC Morales, B Doğançay, J Guo, A Wiedmer, J Domange, M Imeri, R Moos, C Zografou, L Batkitar, L Madrigal, D Schneider, C Trevisan, A Gonzalez-Guerra, A Carrella, IL Dubach, CK Xu, G Meisl, V Kosmoliaptsis, T Malinauskas, N Burgess-Brown, R Owens, S Hatch, J Mongkolsapaya, GR Screaton, K Schubert, JD Huck, F Liu, F Pojer, K Lau, D Hacker, E Probst-Müller, C Cervia, J Nilsson, O Boyman, L Saleh, K Spanaus, A von Eckardstein, DJ Schaer, N Ban, C-J Tsai, J Marino, GFX Schertler, N Ebert, V Thiel, J Gottschalk, BM Frey, RR Reimann, S Hornemann, AM Ring, TPJ Knowles, MA Puhan, CL Althaus, I Xenarios, DI Stuart, A Aguzzi
Iscience
(2023)
26
(doi: 10.1016/j.isci.2023.105928)
Invited speaker Kinetics of protein phase transitions
T Knowles
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2023)
52
RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether
Y Liao, M Fernandopulle, G Wang, H Choi, L Hao, C Drerup, R Patel, S Qamar, J Nixon-Abell, Y Shen, W Meadows, M Vendruscolo, T Knowles, N Matthew, M Czekalska, G Musteikyte, M Gachechiladze, C Stephens, H Pasolli, L Forrest, P St George-Hyslop, J Lippincott-Schwartz, ME Ward
MOLECULAR BIOLOGY OF THE CELL
(2023)
34
Tie-Line Analysis Reveals Interactions Driving Heteromolecular Condensate Formation
D Qian, T Welsh, N Erkamp, S Qamar, J Nixon-Abell, G Krainer, P St George-Hyslop, T Michaels, T Knowles
Physical Review X
(2022)
12
(doi: 10.1103/PhysRevX.12.041038)
A Kinetic Map of the Influence of Biomimetic Lipid Model Membranes on Aβ42 Aggregation.
KN Baumann, G Šneiderienė, M Sanguanini, M Schneider, O Rimon, A González Díaz, H Greer, D Thacker, S Linse, TPJ Knowles, M Vendruscolo
ACS Chemical Neuroscience
(2022)
14
(doi: 10.1021/acschemneuro.2c00765)
Perphenazine-Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid
SR Ball, JSP Adamson, MA Sullivan, MR Zimmermann, V Lo, M Sanz-Hernandez, X Jiang, AH Kwan, ADJ McKenzie, EL Werry, TPJ Knowles, M Kassiou, G Meisl, MH Todd, PJ Rutledge, M Sunde
ACS Chemical Neuroscience
(2022)
14
(doi: 10.1021/acschemneuro.2c00498)
Biomolecular condensate phase diagrams with a combinatorial microdroplet platform.
WE Arter, R Qi, NA Erkamp, G Krainer, K Didi, TJ Welsh, J Acker, J Nixon-Abell, S Qamar, J Guillén-Boixet, TM Franzmann, D Kuster, AA Hyman, A Borodavka, PS George-Hyslop, S Alberti, TPJ Knowles
Nature communications
(2022)
13
(doi: 10.1038/s41467-022-35265-7)
Microfluidics for multiscale studies of biomolecular condensates.
NA Erkamp, R Qi, TJ Welsh, TPJ Knowles
Lab on a Chip
(2022)
23
(doi: 10.1039/d2lc00622g)
Yusuf Hamied Department of Chemistry
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CB2 1EW
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